Protein: MVD1
Diphosphomevalonate decarboxylase (EC 4.1.1.33) (Mevalonate (diphospho)decarboxylase) (MDDase) (Mevalonate pyrophosphate decarboxylase)

Gene: MVD1, MVD
Organism: Homo sapiens
Interactions: 31
UniProt ID: P53602

Gene Ontology (top 5):
GO:0004163 - diphosphomevalonate decarboxylase activity
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0006695 - cholesterol biosynthetic process
GO:0008284 - positive regulation of cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

921496

MVD1
Diphosphomevalonate decarboxylase

1

1

Small-scale

0.647

High

687938

EF1G
Elongation factor 1-gamma

1

2

High-throughput

0.541

High

173685

BTAF1
TATA-binding protein-associated factor 172

1

0

Small-scale

0.529

High

801238

HSPA9
Stress-70 protein, mitochondrial

1

0

Small-scale

0.529

High

163624

GNB5
Guanine nucleotide-binding protein subunit beta-5

1

0

High-throughput

0.518

High

443278

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.513

High

881135

FAS
Fatty acid synthase

1

0

High-throughput

0.513

High

921501

AVR2B
Activin receptor type-2B

1

0

High-throughput

0.513

High

921502

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.513

High

921505

TTLL5
Tubulin polyglutamylase TTLL5

1

0

High-throughput

0.513

High

241177

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

695009

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

861940

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

921498

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.458

High

921508

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

921511

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

921500

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

0

High-throughput

0.438

High

921513

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

921499

VA0D1
V-type proton ATPase subunit d 1

2

0

High-throughput

0.318

High

921497

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.279

Low

921503

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.279

Low

921504

GL8D1
Glycosyltransferase 8 domain-containing protein 1

1

0

High-throughput

0.279

Low

921507

ZN554
Zinc finger protein 554

1

0

High-throughput

0.279

Low

921512

SET1B
Histone-lysine N-methyltransferase SETD1B

1

0

High-throughput

0.279

Low

353139

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

588282

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

921506

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

921510

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

598710

ANFB
Natriuretic peptides B

1

0

High-throughput

0.232

Low

921509

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025