Protein: PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin (Orphanin FQ) (PPNOC); Orphanin FQ2]

Gene: PNOC
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q13519

Gene Ontology (top 5):
GO:0001515 - opioid peptide activity
GO:0005184 - neuropeptide hormone activity
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

832401

OPRX
Nociceptin receptor

3

1

Small-scale

0.651

High

1108890

NISCH
Nischarin

2

0

High-throughput

0.576

High

1108883

WDTC1
WD and tetratricopeptide repeats protein 1

2

1

High-throughput

0.549

High

535029

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.513

High

1108888

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.513

High

1108889

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.513

High

1108881

DCAF6
DDB1- and CUL4-associated factor 6

1

1

High-throughput

0.489

High

1108884

CDC26
Anaphase-promoting complex subunit CDC26

1

1

High-throughput

0.489

High

181623

CETN3
Centrin-3

2

0

High-throughput

0.313

High

291322

NU155
Nuclear pore complex protein Nup155

2

0

High-throughput

0.313

High

1108880

ABRX2
BRISC complex subunit Abraxas 2

1

0

High-throughput

0.279

Low

1108886

WDFY2
WD repeat and FYVE domain-containing protein 2

1

0

High-throughput

0.279

Low

1108887

BABA1
BRISC and BRCA1-A complex member 1

1

0

High-throughput

0.279

Low

1108892

T10B
Mitochondrial import inner membrane translocase subunit Tim10 B

1

0

High-throughput

0.279

Low

1108891

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

1108882

TRI68
E3 ubiquitin-protein ligase TRIM68

1

0

High-throughput

0.232

Low

1108885

ANM6
Protein arginine N-methyltransferase 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025