Protein: PRDM2
PR domain zinc finger protein 2 (EC 2.1.1.355) (GATA-3-binding protein G3B) (Lysine N-methyltransferase 8) (MTB-ZF) (MTE-binding protein) (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc finger protein) (Zinc finger protein RIZ)

Gene: PRDM2
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q13029

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

944645

KLF3
Krueppel-like factor 3

2

19

High-throughput

0.754

High

1092855

CTBP1
C-terminal-binding protein 1

5

8

High-throughput

0.712

High

396013

ESR1
Estrogen receptor

3

14

Small-scale

0.661

High

1092854

PRDM2
PR domain zinc finger protein 2

1

12

Small-scale

0.647

High

442690

RB
Retinoblastoma-associated protein

2

0

Small-scale

0.621

High

339734

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.618

High

1092867

KLF12
Krueppel-like factor 12

1

19

High-throughput

0.618

High

998265

H31
Histone H3.1

2

17

Small-scale

0.595

High

703307

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

6

High-throughput

0.536

High

1092859

NUMA1
Nuclear mitotic apparatus protein 1

1

10

High-throughput

0.536

High

1092861

H2B2E
Histone H2B type 2-E

1

4

High-throughput

0.536

High

1027417

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

4

High-throughput

0.515

High

1013048

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.513

High

1028172

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.501

High

1029071

E2F1
Transcription factor E2F1

1

0

Small-scale

0.480

High

190892

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

246567

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

285249

EED
Polycomb protein EED

1

5

High-throughput

0.479

High

413736

P53
Cellular tumor antigen p53

1

8

Small-scale

0.479

High

442932

PRGR
Progesterone receptor

1

14

Small-scale

0.479

High

473961

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

487255

PARP1
Poly [ADP-ribose] polymerase 1

1

3

High-throughput

0.479

High

557266

SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

Small-scale

0.479

High

717459

PDIA3
Protein disulfide-isomerase A3

1

5

High-throughput

0.479

High

883525

CENPA
Histone H3-like centromeric protein A

1

17

High-throughput

0.479

High

886811

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

979580

H4
Histone H4

1

4

High-throughput

0.479

High

1016816

H33
Histone H3.3

1

17

High-throughput

0.479

High

1067248

EP300
Histone acetyltransferase p300

1

9

Small-scale

0.479

High

1092856

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1092857

CUL3
Cullin-3

1

20

High-throughput

0.479

High

1092858

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1092863

RN123
E3 ubiquitin-protein ligase RNF123

1

4

High-throughput

0.479

High

1092865

NUP43
Nucleoporin Nup43

1

8

High-throughput

0.479

High

402766

CYTB
Cystatin-B

1

0

High-throughput

0.458

High

405192

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.458

High

445851

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

697096

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

1092866

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1056697

FMR1
Fragile X messenger ribonucleoprotein 1

1

7

High-throughput

0.457

High

1092860

H31T
Histone H3.1t

1

17

Small-scale

0.445

High

1092864

DHX40
Probable ATP-dependent RNA helicase DHX40

1

1

High-throughput

0.437

High

1092862

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025