Protein: TREM2
Triggering receptor expressed on myeloid cells 2 (TREM-2) (Triggering receptor expressed on monocytes 2)

Gene: TREM2
Organism: Homo sapiens
Interactions: 15
UniProt ID: Q9NZC2

Gene Ontology (top 5):
GO:0001530 - lipopolysaccharide binding
GO:0001540 - amyloid-beta binding
GO:0001774 - microglial cell activation
GO:0001786 - phosphatidylserine binding
GO:0002116 - semaphorin receptor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1009903

NUCB2
Nucleobindin-2

1

0

High-throughput

0.656

High

1316521

UNC5B
Netrin receptor UNC5B

1

0

Small-scale

0.614

High

231021

TYOBP
TYRO protein tyrosine kinase-binding protein

2

0

Small-scale

0.583

High

890063

PSN1
Presenilin-1

1

0

Small-scale

0.530

High

1453150

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

0

High-throughput

0.513

High

387334

APOA1
Apolipoprotein A-I

1

1

Small-scale

0.501

High

387474

APOE
Apolipoprotein E

1

1

Small-scale

0.501

High

377231

SOMA
Somatotropin

1

0

Small-scale

0.480

High

387569

APOA2
Apolipoprotein A-II

1

0

Small-scale

0.480

High

403234

APOB
Apolipoprotein B-100

1

0

Small-scale

0.480

High

533786

CLUS
Clusterin

1

0

Small-scale

0.480

High

1193256

NRN1L
Neuritin-like protein

1

0

Small-scale

0.480

High

1445896

HM20A
High mobility group protein 20A

1

0

High-throughput

0.438

High

1101429

SG2A2
Mammaglobin-A

1

0

Small-scale

0.261

Low

473144

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025