Protein: APOB
Apolipoprotein B-100 (Apo B-100) [Cleaved into: Apolipoprotein B-48 (Apo B-48)]

Gene: APOB
Organism: Homo sapiens
Interactions: 169
UniProt ID: P04114

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0005543 - phospholipid binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

403150

MTP
Microsomal triglyceride transfer protein large subunit

3

7

Small-scale

0.859

High

403244

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

4

0

Small-scale

0.670

High

387198

APOA1
Apolipoprotein A-I

3

2

Small-scale

0.656

High

403149

TERA
Transitional endoplasmic reticulum ATPase

3

0

Small-scale

0.638

High

403108

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

3

0

High-throughput

0.634

High

403176

TM41B
Transmembrane protein 41B

3

0

High-throughput

0.622

High

403106

APOB
Apolipoprotein B-100

1

7

Small-scale

0.618

High

403119

PDIA4
Protein disulfide-isomerase A4

1

2

Small-scale

0.618

High

376462

LDLR
Low-density lipoprotein receptor

2

3

Small-scale

0.611

High

362564

EGFR
Epidermal growth factor receptor

2

1

High-throughput

0.611

High

403223

P2Y12
P2Y purinoceptor 12

2

2

High-throughput

0.611

High

403162

NTCP7
Sodium/bile acid cotransporter 7

2

0

High-throughput

0.602

High

403179

ZFY27
Protrudin

2

0

High-throughput

0.602

High

403203

SPX3
Sugar phosphate exchanger 3

2

0

High-throughput

0.602

High

403211

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

0

High-throughput

0.602

High

403221

YIPF3
Protein YIPF3

2

0

High-throughput

0.602

High

403224

ZDH11
Palmitoyltransferase ZDHHC11

2

0

High-throughput

0.602

High

403233

NSMA2
Sphingomyelin phosphodiesterase 3

2

0

High-throughput

0.602

High

238346

RAD21
Double-strand-break repair protein rad21 homolog

2

0

High-throughput

0.585

High

403215

DERL1
Derlin-1

2

0

Small-scale

0.585

High

403133

CALX
Calnexin

2

1

Small-scale

0.584

High

240456

PRKN
E3 ubiquitin-protein ligase parkin

2

0

High-throughput

0.559

High

403117

ACTN1
Alpha-actinin-1

2

0

High-throughput

0.559

High

403155

RS6
Small ribosomal subunit protein eS6

2

0

High-throughput

0.559

High

403206

FAF2
FAS-associated factor 2

2

0

Small-scale

0.559

High

403177

TM128
Transmembrane protein 128

2

1

High-throughput

0.558

High

67035

IFM5
Interferon-induced transmembrane protein 5

1

1

High-throughput

0.536

High

210673

KLK10
Kallikrein-10

1

2

High-throughput

0.536

High

403116

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

2

High-throughput

0.536

High

403147

NEK4
Serine/threonine-protein kinase Nek4

1

1

High-throughput

0.536

High

403160

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.536

High

403190

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

1

Small-scale

0.536

High

403208

ARX
Homeobox protein ARX

1

2

High-throughput

0.536

High

403169

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.515

High

403189

TM11B
Transmembrane protease serine 11B

1

1

High-throughput

0.515

High

132982

MATN2
Matrilin-2

1

0

High-throughput

0.513

High

141807

ACKR2
Atypical chemokine receptor 2

1

0

High-throughput

0.513

High

178888

SCAM2
Secretory carrier-associated membrane protein 2

1

0

High-throughput

0.513

High

184102

RER1
Protein RER1

1

0

High-throughput

0.513

High

219266

B4GA1
Beta-1,4-glucuronyltransferase 1

1

0

High-throughput

0.513

High

226301

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

359897

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.513

High

403114

BIP
Endoplasmic reticulum chaperone BiP

1

0

Small-scale

0.513

High

403125

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.513

High

403129

NK1R
Substance-P receptor

1

0

High-throughput

0.513

High

403130

PAX6
Paired box protein Pax-6

1

0

High-throughput

0.513

High

403137

MYH9
Myosin-9

1

0

High-throughput

0.513

High

403140

P2RY2
P2Y purinoceptor 2

1

0

High-throughput

0.513

High

403141

S19A1
Reduced folate transporter

1

0

High-throughput

0.513

High

403144

CRKL
Crk-like protein

1

0

High-throughput

0.513

High

403161

MZT1
Mitotic-spindle organizing protein 1

1

0

High-throughput

0.513

High

403165

MALL
MAL-like protein

1

0

High-throughput

0.513

High

403174

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.513

High

403185

GOT1A
Vesicle transport protein GOT1A

1

0

High-throughput

0.513

High

403191

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.513

High

403205

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.513

High

403213

SELS
Selenoprotein S

1

0

Small-scale

0.513

High

403214

TM208
Transmembrane protein 208

1

0

High-throughput

0.513

High

403225

CERS4
Ceramide synthase 4

1

0

High-throughput

0.513

High

403226

ELOV3
Very long chain fatty acid elongase 3

1

0

High-throughput

0.513

High

403228

ANLN
Anillin

1

0

High-throughput

0.513

High

403231

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

0

High-throughput

0.513

High

403232

GP173
Probable G-protein coupled receptor 173

1

0

High-throughput

0.513

High

403236

CKLF
Chemokine-like factor

1

0

High-throughput

0.513

High

403239

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

0

High-throughput

0.513

High

403240

SC5A6
Sodium-dependent multivitamin transporter

1

0

High-throughput

0.513

High

287509

LRP6
Low-density lipoprotein receptor-related protein 6

1

2

Small-scale

0.501

High

403112

HS90A
Heat shock protein HSP 90-alpha

1

1

Small-scale

0.501

High

403115

LIPC
Hepatic triacylglycerol lipase

1

3

Small-scale

0.501

High

350206

FADS2
Acyl-CoA 6-desaturase

1

0

High-throughput

0.493

High

403121

CD36
Platelet glycoprotein 4

1

0

Small-scale

0.480

High

403126

PGS1
Biglycan

1

0

Small-scale

0.480

High

403159

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.480

High

403234

TREM2
Triggering receptor expressed on myeloid cells 2

1

0

Small-scale

0.480

High

125134

LEG9
Galectin-9

1

1

Small-scale

0.479

High

156827

CTRO
Citron Rho-interacting kinase

1

3

High-throughput

0.479

High

370889

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

374329

RASH
GTPase HRas

1

1

High-throughput

0.479

High

403107

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

403118

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

403120

ENPL
Endoplasmin

1

1

Small-scale

0.479

High

403123

LEG3
Galectin-3

1

1

Small-scale

0.479

High

403124

VGFR1
Vascular endothelial growth factor receptor 1

1

1

High-throughput

0.479

High

403132

CALR
Calreticulin

1

1

Small-scale

0.479

High

403138

TRI23
E3 ubiquitin-protein ligase TRIM23

1

2

High-throughput

0.479

High

403139

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

1

High-throughput

0.479

High

403142

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.479

High

403148

VMAT1
Chromaffin granule amine transporter

1

2

High-throughput

0.479

High

403153

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

2

Small-scale

0.479

High

403163

NEXN
Nexilin

1

1

High-throughput

0.479

High

403168

CUL3
Cullin-3

1

1

High-throughput

0.479

High

403171

TNIP1
TNFAIP3-interacting protein 1

1

2

High-throughput

0.479

High

403173

P2Y14
P2Y purinoceptor 14

1

2

High-throughput

0.479

High

403178

TGO1
Transport and Golgi organization protein 1 homolog

1

1

Small-scale

0.479

High

403229

TMPS4
Transmembrane protease serine 4

1

1

High-throughput

0.479

High

403135

AKT2
RAC-beta serine/threonine-protein kinase

1

0

High-throughput

0.460

High

403158

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.460

High

403166

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.460

High

403201

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.460

High

330559

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

365258

PGK1
Phosphoglycerate kinase 1

1

0

High-throughput

0.458

High

389914

ALBU
Albumin

1

0

High-throughput

0.458

High

400084

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

403111

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

403113

SAA2
Serum amyloid A-2 protein

1

0

High-throughput

0.458

High

403122

CXA1
Gap junction alpha-1 protein

1

0

Small-scale

0.458

High

403128

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

Small-scale

0.458

High

403131

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

403134

CALCR
Calcitonin receptor

1

0

Small-scale

0.458

High

403145

CTCF
Transcriptional repressor CTCF

1

0

Small-scale

0.458

High

403146

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

403151

MLF1
Myeloid leukemia factor 1

1

0

High-throughput

0.458

High

403152

SC61B
Protein transport protein Sec61 subunit beta

1

0

Small-scale

0.458

High

403156

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

403157

YBOX1
Y-box-binding protein 1

1

0

Small-scale

0.458

High

403164

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.458

High

403167

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

403170

CUL7
Cullin-7

1

0

High-throughput

0.458

High

403196

S38A6
Solute carrier family 38 member 6

1

0

High-throughput

0.458

High

403210

PLIN2
Perilipin-2

1

0

Small-scale

0.458

High

403212

ANM1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.458

High

403217

FACD2
Fanconi anemia group D2 protein

1

0

High-throughput

0.458

High

403218

TRIM6
Tripartite motif-containing protein 6

1

0

Small-scale

0.458

High

403219

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.458

High

403222

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

403235

MYOF
Myoferlin

1

0

High-throughput

0.458

High

403237

TBK1
Serine/threonine-protein kinase TBK1

1

0

High-throughput

0.458

High

403243

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

0

Small-scale

0.458

High

403184

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.457

High

403127

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

2

High-throughput

0.445

High

403136

BMI1
Polycomb complex protein BMI-1

1

1

High-throughput

0.445

High

403175

KLH22
Kelch-like protein 22

1

1

High-throughput

0.445

High

403183

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

2

High-throughput

0.445

High

403187

MOT14
Monocarboxylate transporter 14

1

1

High-throughput

0.445

High

277249

PITX3
Pituitary homeobox 3

1

2

Small-scale

0.437

High

403186

ASXL2
Putative Polycomb group protein ASXL2

1

2

High-throughput

0.437

High

403193

ASXL1
Polycomb group protein ASXL1

1

2

High-throughput

0.437

High

403216

YIPF2
Protein YIPF2

1

1

High-throughput

0.437

High

403220

ASXL3
Putative Polycomb group protein ASXL3

1

2

High-throughput

0.437

High

403241

TRRAP
Transformation/transcription domain-associated protein

1

1

High-throughput

0.437

High

403109

IPSP
Plasma serine protease inhibitor

1

0

Small-scale

0.426

High

403110

PRGR
Progesterone receptor

1

0

Small-scale

0.426

High

403143

SATT
Neutral amino acid transporter A

1

0

High-throughput

0.426

High

403154

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

0

High-throughput

0.426

High

403181

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

403194

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.426

High

403197

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.426

High

403199

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.426

High

403204

MFSD8
Major facilitator superfamily domain-containing protein 8

1

0

High-throughput

0.426

High

403209

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

403227

S6A20
Sodium- and chloride-dependent transporter XTRP3

1

0

High-throughput

0.426

High

85142

B7Z3K1
cDNA FLJ51973

1

1

High-throughput

0.407

High

49727

TMM72
Transmembrane protein 72

1

0

High-throughput

0.279

Low

403180

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

0

High-throughput

0.279

Low

403182

STUM
Protein stum homolog

1

0

High-throughput

0.279

Low

403192

S22A9
Organic anion transporter 7

1

0

High-throughput

0.279

Low

403198

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

403200

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

0

High-throughput

0.279

Low

403202

S43A3
Equilibrative nucleobase transporter 1

1

0

High-throughput

0.279

Low

403230

KISHB
Protein kish-B

1

0

High-throughput

0.279

Low

403238

PHF11
PHD finger protein 11

1

0

High-throughput

0.279

Low

403242

T184B
Transmembrane protein 184B

1

0

High-throughput

0.279

Low

229180

B3GT2
Beta-1,3-galactosyltransferase 2

1

0

High-throughput

0.249

Low

352284

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.249

Low

403172

NONO
Non-POU domain-containing octamer-binding protein

1

0

High-throughput

0.249

Low

403195

TM192
Transmembrane protein 192

1

0

High-throughput

0.249

Low

403188

S35E3
Solute carrier family 35 member E3

1

0

High-throughput

0.232

Low

403207

TM169
Transmembrane protein 169

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025