Protein: KHK
Ketohexokinase (EC 2.7.1.3) (Hepatic fructokinase)

Gene: KHK
Organism: Homo sapiens
Interactions: 23
UniProt ID: P50053

Gene Ontology (top 5):
GO:0004454 - ketohexokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006000 - fructose metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

893021

CUED2
CUE domain-containing protein 2

2

0

High-throughput

0.602

High

893023

LHX9
LIM/homeobox protein Lhx9

2

1

High-throughput

0.597

High

893012

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

1

Small-scale

0.586

High

593648

BGAL
Beta-galactosidase

2

0

High-throughput

0.585

High

893018

APBP2
Amyloid protein-binding protein 2

2

0

High-throughput

0.580

High

893010

LHX2
LIM/homeobox protein Lhx2

2

1

High-throughput

0.553

High

893019

CSN5
COP9 signalosome complex subunit 5

1

2

High-throughput

0.536

High

253429

CST8
Cystatin-8

1

0

High-throughput

0.513

High

893024

SPG21
Maspardin

1

0

High-throughput

0.513

High

289073

DEDD
Death effector domain-containing protein

1

0

High-throughput

0.493

High

335793

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

0

High-throughput

0.493

High

574175

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.493

High

882412

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.493

High

893013

LYSC
Lysozyme C

1

0

High-throughput

0.493

High

893015

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.493

High

893020

CK5P3
CDK5 regulatory subunit-associated protein 3

1

0

High-throughput

0.493

High

893011

AP2S1
AP-2 complex subunit sigma

1

0

High-throughput

0.458

High

893014

ILK
Scaffold protein ILK

1

0

High-throughput

0.458

High

893022

RANB3
Ran-binding protein 3

1

0

High-throughput

0.458

High

893017

DJB14
DnaJ homolog subfamily B member 14

2

0

High-throughput

0.319

High

723909

LCN1
Lipocalin-1

1

0

High-throughput

0.269

Low

846044

GLP1R
Glucagon-like peptide 1 receptor

1

0

Small-scale

0.251

Low

893016

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025