Protein: CUED2
CUE domain-containing protein 2

Gene: CUED2, CUEDC2
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q9H467

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0010936 - negative regulation of macrophage cytokine production
GO:0031965 - nuclear membrane
GO:0043130 - ubiquitin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1433162

FZR1
Fizzy-related protein homolog

6

1

Small-scale

0.729

High

628842

TBP
TATA-box-binding protein

4

1

High-throughput

0.695

High

508619

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

Small-scale

0.687

High

893021

KHK
Ketohexokinase

2

0

High-throughput

0.602

High

396935

ESR1
Estrogen receptor

2

1

Small-scale

0.601

High

442958

PRGR
Progesterone receptor

1

1

Small-scale

0.598

High

1033225

EWS
RNA-binding protein EWS

2

0

High-throughput

0.588

High

1433161

UBQL2
Ubiquilin-2

1

0

High-throughput

0.586

High

155967

SOCS3
Suppressor of cytokine signaling 3

1

1

Small-scale

0.573

High

167973

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

2

Small-scale

0.573

High

177946

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

2

Small-scale

0.573

High

193306

SOCS1
Suppressor of cytokine signaling 1

1

1

Small-scale

0.561

High

718627

CDC27
Cell division cycle protein 27 homolog

2

0

Small-scale

0.559

High

294752

PR15A
Protein phosphatase 1 regulatory subunit 15A

1

0

Small-scale

0.549

High

288016

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.518

High

967966

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

Small-scale

0.515

High

530375

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

868596

RL29
Large ribosomal subunit protein eL29

1

0

High-throughput

0.513

High

913282

T2AG
Transcription initiation factor IIA subunit 2

1

0

High-throughput

0.513

High

1152959

NAB2
NGFI-A-binding protein 2

1

0

High-throughput

0.513

High

691847

MK03
Mitogen-activated protein kinase 3

1

1

Small-scale

0.501

High

703706

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.501

High

786847

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

High-throughput

0.479

High

1086910

CDC20
Cell division cycle protein 20 homolog

1

1

Small-scale

0.479

High

1431536

VP33B
Vacuolar protein sorting-associated protein 33B

1

1

High-throughput

0.479

High

1181246

Q32MN6
TBP protein

1

1

High-throughput

0.470

High

593216

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

Small-scale

0.458

High

675161

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.458

High

696492

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

761876

HSP74
Heat shock 70 kDa protein 4

1

0

Small-scale

0.458

High

913265

TF2AA
Transcription initiation factor IIA subunit 1

1

0

High-throughput

0.458

High

954270

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

1099779

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

Small-scale

0.458

High

1433160

ZO2
Tight junction protein 2

1

0

High-throughput

0.458

High

1383674

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.437

High

1417850

RNF26
E3 ubiquitin-protein ligase RNF26

3

0

High-throughput

0.347

High

720697

AGTR1
Type-1 angiotensin II receptor

1

0

High-throughput

0.282

High

596533

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1041287

CAV1
Caveolin-1

1

0

High-throughput

0.279

Low

648672

FGFR4
Fibroblast growth factor receptor 4

1

0

High-throughput

0.249

Low

801524

HSPA9
Stress-70 protein, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025