Protein: DEDD
Death effector domain-containing protein (DEDPro1) (Death effector domain-containing testicular molecule) (FLDED-1)

Gene: DEDD
Organism: Homo sapiens
Interactions: 38
UniProt ID: O75618

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0007283 - spermatogenesis
GO:0008625 - extrinsic apoptotic signaling pathway via death domain receptors

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

289082

CASP8
Caspase-8

3

5

Small-scale

0.870

High

289080

FADD
FAS-associated death domain protein

3

6

Small-scale

0.857

High

289063

DEDD
Death effector domain-containing protein

3

2

Small-scale

0.847

High

289089

DEDD2
DNA-binding death effector domain-containing protein 2

2

2

Small-scale

0.843

High

192976

CFLAR
CASP8 and FADD-like apoptosis regulator

3

5

Small-scale

0.834

High

289066

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.656

High

289090

CASPA
Caspase-10

1

5

Small-scale

0.618

High

289064

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.602

High

289085

FBX38
F-box only protein 38

2

1

Small-scale

0.584

High

289078

APLP2
Amyloid beta precursor like protein 2

1

1

High-throughput

0.578

High

289076

SKP1
S-phase kinase-associated protein 1

2

0

High-throughput

0.576

High

289081

DNJC3
DnaJ homolog subfamily C member 3

2

0

High-throughput

0.576

High

289098

TF3C3
General transcription factor 3C polypeptide 3

1

2

Small-scale

0.573

High

289077

SMAD3
Mothers against decapentaplegic homolog 3

1

0

Small-scale

0.561

High

289068

CCNB1
G2/mitotic-specific cyclin-B1

1

1

Small-scale

0.554

High

289092

DYL2
Dynein light chain 2, cytoplasmic

2

1

High-throughput

0.549

High

289075

DYL1
Dynein light chain 1, cytoplasmic

1

1

High-throughput

0.536

High

289074

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

High-throughput

0.513

High

289079

CAF1B
Chromatin assembly factor 1 subunit B

1

0

High-throughput

0.513

High

289097

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.513

High

289073

KHK
Ketohexokinase

1

0

High-throughput

0.493

High

289095

RANB3
Ran-binding protein 3

1

0

High-throughput

0.493

High

289071

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.460

High

289065

K1C18
Keratin, type I cytoskeletal 18

1

0

Small-scale

0.458

High

289070

ARI4A
AT-rich interactive domain-containing protein 4A

1

0

High-throughput

0.458

High

289091

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

1

High-throughput

0.437

High

289067

HXD4
Homeobox protein Hox-D4

1

0

High-throughput

0.282

High

289088

BATF2
Basic leucine zipper transcriptional factor ATF-like 2

1

0

High-throughput

0.282

High

289096

TAP26
Thyroid transcription factor 1-associated protein 26

1

0

High-throughput

0.269

Low

289069

AMD
Peptidyl-glycine alpha-amidating monooxygenase

1

0

High-throughput

0.249

Low

289072

VATE1
V-type proton ATPase subunit E 1

1

0

High-throughput

0.249

Low

289084

TCAL5
Transcription elongation factor A protein-like 5

1

0

High-throughput

0.249

Low

289086

RSRC2
Arginine/serine-rich coiled-coil protein 2

1

0

High-throughput

0.249

Low

289087

ABCA9
ATP-binding cassette sub-family A member 9

1

0

High-throughput

0.249

Low

289093

LTV1
Protein LTV1 homolog

1

0

High-throughput

0.249

Low

289094

NEUS
Neuroserpin

1

0

High-throughput

0.249

Low

289083

AT7L3
Ataxin-7-like protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025