Protein: LCN1
Lipocalin-1 (Tear lipocalin) (Tlc) (Tear prealbumin) (TP) (von Ebner gland protein) (VEG protein)

Gene: LCN1
Organism: Homo sapiens
Interactions: 104
UniProt ID: P31025

Gene Ontology (top 5):
GO:0004869 - cysteine-type endopeptidase inhibitor activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

723959

PECR
Peroxisomal trans-2-enoyl-CoA reductase

3

0

High-throughput

0.638

High

377090

PDYN
Proenkephalin-B

3

0

High-throughput

0.629

High

389649

A1AG1
Alpha-1-acid glycoprotein 1

1

1

High-throughput

0.618

High

488205

LOX5
Polyunsaturated fatty acid 5-lipoxygenase

2

0

High-throughput

0.580

High

723927

HBM
Hemoglobin subunit mu

2

1

High-throughput

0.574

High

723944

DNJB8
DnaJ homolog subfamily B member 8

2

1

High-throughput

0.574

High

723952

SNX27
Sorting nexin-27

2

1

High-throughput

0.574

High

723963

DDX31
ATP-dependent DNA helicase DDX31

2

2

High-throughput

0.574

High

723970

UBQL2
Ubiquilin-2

2

4

High-throughput

0.553

High

141992

FCN1
Ficolin-1

1

1

High-throughput

0.536

High

210719

KLK10
Kallikrein-10

1

1

High-throughput

0.536

High

723915

UBE3A
Ubiquitin-protein ligase E3A

1

1

High-throughput

0.536

High

723947

ITLN2
Intelectin-2

1

1

High-throughput

0.536

High

723955

EGFL8
Epidermal growth factor-like protein 8

1

4

High-throughput

0.536

High

723975

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.536

High

355435

NSD2
Histone-lysine N-methyltransferase NSD2

1

0

High-throughput

0.513

High

723938

WDFY3
WD repeat and FYVE domain-containing protein 3

1

0

High-throughput

0.513

High

723941

GOLM1
Golgi membrane protein 1

1

0

High-throughput

0.513

High

723945

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

0

High-throughput

0.513

High

67427

GOG8A
Golgin subfamily A member 8A

1

1

High-throughput

0.489

High

133848

FOXN3
Forkhead box protein N3

1

1

High-throughput

0.489

High

335232

CXB5
Gap junction beta-5 protein

1

1

High-throughput

0.489

High

473665

ITA5
Integrin alpha-5

1

6

High-throughput

0.489

High

723910

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

1

High-throughput

0.489

High

723911

JAK3
Tyrosine-protein kinase JAK3

1

3

High-throughput

0.489

High

723923

T176B
Transmembrane protein 176B

1

1

High-throughput

0.489

High

723924

KLH22
Kelch-like protein 22

1

2

High-throughput

0.489

High

723929

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

1

High-throughput

0.489

High

723931

SFXN4
Sideroflexin-4

1

1

High-throughput

0.489

High

723967

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

3

High-throughput

0.489

High

352005

RECK
Reversion-inducing cysteine-rich protein with Kazal motifs

1

1

High-throughput

0.481

High

302392

RNF8
E3 ubiquitin-protein ligase RNF8

1

2

High-throughput

0.479

High

369318

A1AT
Alpha-1-antitrypsin

1

1

High-throughput

0.479

High

369442

AACT
Alpha-1-antichymotrypsin

1

1

High-throughput

0.479

High

390277

VTDB
Vitamin D-binding protein

1

1

High-throughput

0.479

High

390868

TRFE
Serotransferrin

1

1

High-throughput

0.479

High

391127

HEMO
Hemopexin

1

2

High-throughput

0.479

High

472279

CFAH
Complement factor H

1

1

Small-scale

0.479

High

723913

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.479

High

723917

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

723918

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

723921

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

723948

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

723949

DPF3
Zinc finger protein DPF3

1

3

Small-scale

0.479

High

723928

ALKB2
DNA oxidative demethylase ALKBH2

1

1

High-throughput

0.470

High

75149

FM25C
Protein FAM25C

1

3

High-throughput

0.470

High

723932

Q6P9E2
RECK protein

1

1

High-throughput

0.470

High

141335

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

361526

CERU
Ceruloplasmin

1

0

High-throughput

0.458

High

366155

HPT
Haptoglobin

1

0

High-throughput

0.458

High

387241

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.458

High

391727

STAT
Statherin

1

0

High-throughput

0.458

High

413269

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

671759

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.458

High

722770

AL3A1
Aldehyde dehydrogenase, dimeric NADP-preferring

1

0

Small-scale

0.458

High

723922

PROL4
Proline-rich protein 4

1

0

High-throughput

0.458

High

723936

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

723960

TRIM6
Tripartite motif-containing protein 6

1

0

Small-scale

0.458

High

723965

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

723974

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

75130

FM25A
Protein FAM25A

1

3

High-throughput

0.439

High

411436

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

723920

CUL4A
Cullin-4A

1

1

High-throughput

0.437

High

723950

KISSR
KiSS-1 receptor

1

3

Small-scale

0.437

High

723954

RANB9
Ran-binding protein 9

1

1

High-throughput

0.437

High

723957

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

2

High-throughput

0.437

High

723958

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.437

High

723961

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

1

High-throughput

0.437

High

723962

DDX24
ATP-dependent RNA helicase DDX24

1

1

High-throughput

0.437

High

723968

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

1

High-throughput

0.437

High

723919

STK4
Serine/threonine-protein kinase 4

1

3

High-throughput

0.407

High

723926

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.407

High

221088

SPY2
Protein sprouty homolog 2

1

0

High-throughput

0.279

Low

225358

ERD23
ER lumen protein-retaining receptor 3

1

0

High-throughput

0.279

Low

273336

NPHP4
Nephrocystin-4

1

0

High-throughput

0.279

Low

425881

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

0

High-throughput

0.279

Low

472236

MYL3
Myosin light chain 3

1

0

High-throughput

0.279

Low

723914

RT05
Small ribosomal subunit protein uS5m

1

0

High-throughput

0.279

Low

723925

ATAT
Alpha-tubulin N-acetyltransferase 1

1

0

High-throughput

0.279

Low

723930

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.279

Low

723933

SYDM
Aspartate--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

723935

SPNS3
Protein spinster homolog 3

1

0

High-throughput

0.279

Low

723939

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.279

Low

723940

AT11C
Phospholipid-transporting ATPase IG

1

0

High-throughput

0.279

Low

723942

TM116
Transmembrane protein 116

1

0

High-throughput

0.279

Low

723946

CAPSL
Calcyphosin-like protein

1

0

High-throughput

0.279

Low

723951

PMEPA
Protein TMEPAI

1

0

High-throughput

0.279

Low

723953

CRML
Protein cramped-like

1

0

High-throughput

0.279

Low

723956

YJU2
Splicing factor YJU2

1

0

High-throughput

0.279

Low

723964

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.279

Low

723966

PLS4
Phospholipid scramblase 4

1

0

High-throughput

0.279

Low

723971

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.279

Low

723973

TDRKH
Tudor and KH domain-containing protein

1

0

High-throughput

0.279

Low

723976

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.279

Low

723909

KHK
Ketohexokinase

1

0

High-throughput

0.269

Low

723943

SPAT4
Spermatogenesis-associated protein 4

1

0

High-throughput

0.269

Low

723934

LMBRL
Protein LMBR1L

1

0

Small-scale

0.261

Low

293265

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

723912

EFNA3
Ephrin-A3

1

0

High-throughput

0.249

Low

723916

FOXO1
Forkhead box protein O1

1

0

High-throughput

0.249

Low

723937

MILK2
MICAL-like protein 2

1

0

High-throughput

0.249

Low

723969

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.249

Low

723972

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low

587012

ITF2
Transcription factor 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025