Protein: NFRKB
Nuclear factor related to kappa-B-binding protein (DNA-binding protein R kappa-B) (INO80 complex subunit G)

Gene: NFRKB
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q6P4R8

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0002020 - protease binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1242511

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

15

3

Small-scale

0.763

High

1242506

INO80
Chromatin-remodeling ATPase INO80

6

4

Small-scale

0.730

High

675549

TYY1
Transcriptional repressor protein YY1

5

4

High-throughput

0.722

High

1242507

RUVB2
RuvB-like 2

5

5

High-throughput

0.718

High

1242508

RUVB1
RuvB-like 1

5

5

High-throughput

0.716

High

1242479

IN80E
INO80 complex subunit E

7

0

Small-scale

0.708

High

610379

PRS6A
26S proteasome regulatory subunit 6A

3

2

High-throughput

0.667

High

1242510

CARD8
Caspase recruitment domain-containing protein 8

3

1

High-throughput

0.667

High

503608

TFPT
TCF3 fusion partner

4

0

High-throughput

0.653

High

332522

CCDB1
Cyclin-D1-binding protein 1

3

0

High-throughput

0.638

High

1200557

IN80D
INO80 complex subunit D

3

2

High-throughput

0.633

High

1242488

MCRS1
Microspherule protein 1

3

1

High-throughput

0.633

High

1242497

ARP8
Actin-related protein 8

3

9

High-throughput

0.633

High

1242498

ARP5
Actin-related protein 5

2

10

High-throughput

0.611

High

212431

SPIT2
Kunitz-type protease inhibitor 2

3

1

High-throughput

0.609

High

954507

PRPS1
Ribose-phosphate pyrophosphokinase 1

3

1

High-throughput

0.609

High

1010056

DLK1
Protein delta homolog 1

3

1

High-throughput

0.609

High

1242494

IN80B
INO80 complex subunit B

3

0

High-throughput

0.606

High

1242481

BCL7C
B-cell CLL/lymphoma 7 protein family member C

2

1

High-throughput

0.601

High

1242474

IN80C
INO80 complex subunit C

2

0

High-throughput

0.585

High

372329

MYC
Myc proto-oncogene protein

2

12

High-throughput

0.584

High

1133476

NFIX
Nuclear factor 1 X-type

2

20

High-throughput

0.584

High

1141180

BRD3
Bromodomain-containing protein 3

2

10

High-throughput

0.584

High

1242505

KLF15
Krueppel-like factor 15

2

13

High-throughput

0.584

High

941354

CAV3
Caveolin-3

2

3

High-throughput

0.574

High

1242504

I20RA
Interleukin-20 receptor subunit alpha

2

2

High-throughput

0.574

High

1242513

EMIL1
EMILIN-1

2

6

High-throughput

0.574

High

396342

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1242495

CARD9
Caspase recruitment domain-containing protein 9

2

1

High-throughput

0.558

High

384455

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.536

High

952901

ACTB
Actin, cytoplasmic 1

1

8

High-throughput

0.536

High

969922

RS16
Small ribosomal subunit protein uS9

1

2

High-throughput

0.536

High

1112880

CUL2
Cullin-2

1

8

High-throughput

0.536

High

1160172

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

7

High-throughput

0.536

High

1242483

PSPC1
Paraspeckle component 1

1

2

High-throughput

0.536

High

161673

TRDMT
tRNA

1

0

High-throughput

0.518

High

1009798

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.513

High

931811

EPHB3
Ephrin type-B receptor 3

1

5

High-throughput

0.494

High

347113

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.489

High

549617

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.489

High

630299

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

3

High-throughput

0.489

High

1180394

KLH40
Kelch-like protein 40

1

1

High-throughput

0.489

High

1203693

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.489

High

1228665

C102B
Coiled-coil domain-containing protein 102B

1

3

High-throughput

0.489

High

1242478

I22R1
Interleukin-22 receptor subunit alpha-1

1

2

High-throughput

0.489

High

1242489

VPS39
Vam6/Vps39-like protein

1

3

High-throughput

0.489

High

130513

SPT5H
Transcription elongation factor SPT5

1

9

High-throughput

0.479

High

143058

NFIB
Nuclear factor 1 B-type

1

17

High-throughput

0.479

High

210028

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

339782

KLF8
Krueppel-like factor 8

1

16

High-throughput

0.479

High

355233

ACL6A
Actin-like protein 6A

1

8

High-throughput

0.479

High

414042

P53
Cellular tumor antigen p53

1

6

High-throughput

0.479

High

461601

HS90A
Heat shock protein HSP 90-alpha

1

6

High-throughput

0.479

High

468504

HS90B
Heat shock protein HSP 90-beta

1

6

High-throughput

0.479

High

474069

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

520140

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

538417

EGR2
E3 SUMO-protein ligase EGR2

1

6

High-throughput

0.479

High

577451

ETS1
Protein C-ets-1

1

16

High-throughput

0.479

High

588952

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

640923

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

2

High-throughput

0.479

High

674213

BRD2
Bromodomain-containing protein 2

1

10

High-throughput

0.479

High

685236

PAX6
Paired box protein Pax-6

1

13

High-throughput

0.479

High

695738

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

714203

PML
Protein PML

1

9

High-throughput

0.479

High

738997

ELF1
ETS-related transcription factor Elf-1

1

19

High-throughput

0.479

High

768457

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

775864

HNF1B
Hepatocyte nuclear factor 1-beta

1

17

High-throughput

0.479

High

799939

COIL
Coilin

1

1

High-throughput

0.479

High

833971

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

862230

YAP1
Transcriptional coactivator YAP1

1

12

High-throughput

0.479

High

879197

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

5

High-throughput

0.479

High

886964

CEBPA
CCAAT/enhancer-binding protein alpha

1

10

High-throughput

0.479

High

944685

KLF3
Krueppel-like factor 3

1

16

High-throughput

0.479

High

979846

H4
Histone H4

1

5

High-throughput

0.479

High

980855

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.479

High

995088

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.479

High

998451

H31
Histone H3.1

1

15

High-throughput

0.479

High

1016957

H33
Histone H3.3

1

15

High-throughput

0.479

High

1033030

EWS
RNA-binding protein EWS

1

8

High-throughput

0.479

High

1048007

TLE3
Transducin-like enhancer protein 3

1

10

High-throughput

0.479

High

1087810

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1097361

CBX3
Chromobox protein homolog 3

1

12

High-throughput

0.479

High

1149912

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

1152701

ELF2
ETS-related transcription factor Elf-2

1

18

High-throughput

0.479

High

1242476

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

8

High-throughput

0.479

High

1242477

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

1242480

NUP43
Nucleoporin Nup43

1

16

High-throughput

0.479

High

1242484

SYNE2
Nesprin-2

1

4

High-throughput

0.479

High

1242485

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1242486

LHX4
LIM/homeobox protein Lhx4

1

17

High-throughput

0.479

High

1242487

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

15

High-throughput

0.479

High

1242491

FEV
Protein FEV

1

15

High-throughput

0.479

High

1242492

ELF4
ETS-related transcription factor Elf-4

1

19

High-throughput

0.479

High

1242493

KLF16
Krueppel-like factor 16

1

11

High-throughput

0.479

High

1242500

NLE1
Notchless protein homolog 1

1

5

High-throughput

0.479

High

1242502

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

3

High-throughput

0.479

High

1242503

LHX3
LIM/homeobox protein Lhx3

1

17

High-throughput

0.479

High

1242509

ASF1A
Histone chaperone ASF1A

1

6

High-throughput

0.479

High

1005893

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

1025924

NDP
Norrin

1

0

Small-scale

0.458

High

1119568

NFYC
Nuclear transcription factor Y subunit gamma

1

0

High-throughput

0.458

High

1242475

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

1056795

FMR1
Fragile X messenger ribonucleoprotein 1

1

4

High-throughput

0.457

High

302861

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

13

High-throughput

0.437

High

323435

TRI37
E3 ubiquitin-protein ligase TRIM37

1

7

High-throughput

0.437

High

991865

DYLT1
Dynein light chain Tctex-type 1

1

1

High-throughput

0.437

High

1242501

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

1156457

ADRM1
Proteasomal ubiquitin receptor ADRM1

1

0

Small-scale

0.426

High

1226891

A16L1
Autophagy-related protein 16-1

1

13

High-throughput

0.407

High

1242499

RAB18
Ras-related protein Rab-18

1

1

High-throughput

0.407

High

1242512

KPTN
KICSTOR complex protein kaptin

3

0

High-throughput

0.347

High

1242496

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.328

High

1242490

TMM74
Transmembrane protein 74

2

0

High-throughput

0.313

High

596493

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.279

Low

1195232

TM52B
Transmembrane protein 52B

1

0

High-throughput

0.279

Low

1238233

CK087
Uncharacterized protein C11orf87

1

0

High-throughput

0.279

Low

1242482

TM171
Transmembrane protein 171

1

0

High-throughput

0.279

Low

1242514

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.279

Low

1158382

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025