Protein: ERG28
Ergosterol biosynthetic protein 28 homolog

Gene: ERG28
Organism: Homo sapiens
Interactions: 147
UniProt ID: Q9UKR5

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0016020 - membrane
GO:0016126 - sterol biosynthetic process
GO:0030133 - transport vesicle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

832657

AQP2
Aquaporin-2

3

2

Small-scale

0.654

High

1154084

MSMO1
Methylsterol monooxygenase 1

3

2

Small-scale

0.654

High

1461196

ERG28
Ergosterol biosynthetic protein 28 homolog

3

2

Small-scale

0.654

High

1452326

SCN3B
Sodium channel regulatory subunit beta-3

3

0

High-throughput

0.636

High

138584

CLD5
Claudin-5

2

1

High-throughput

0.606

High

258674

G37L1
G-protein coupled receptor 37-like 1

2

2

High-throughput

0.606

High

1363253

AQP3
Aquaporin-3

2

2

High-throughput

0.606

High

1384379

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.606

High

1447912

SAR1A
Small COPII coat GTPase SAR1A

2

1

High-throughput

0.606

High

129902

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.580

High

167023

MGST3
Glutathione S-transferase 3, mitochondrial

2

0

High-throughput

0.580

High

337149

NPT2B
Sodium-dependent phosphate transport protein 2B

2

0

High-throughput

0.580

High

337838

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.580

High

407142

HG2A
HLA class II histocompatibility antigen gamma chain

2

0

High-throughput

0.580

High

690426

STOM
Stomatin

2

0

High-throughput

0.580

High

883453

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.580

High

1132592

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

1142971

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.580

High

1187302

PIGY
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

2

0

High-throughput

0.580

High

1210325

MF14B
Hippocampus abundant transcript-like protein 1

2

0

High-throughput

0.580

High

1291522

RETR3
Reticulophagy regulator 3

2

0

High-throughput

0.580

High

1328224

JAGN1
Protein jagunal homolog 1

2

0

High-throughput

0.580

High

1334057

DHB11
Estradiol 17-beta-dehydrogenase 11

2

0

High-throughput

0.580

High

1349147

F174A
Membrane protein FAM174A

2

0

High-throughput

0.580

High

1352551

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.580

High

1359336

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.580

High

1388145

T4S19
Transmembrane 4 L6 family member 19

2

0

High-throughput

0.580

High

1398492

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

1416997

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.580

High

1417366

S26A6
Solute carrier family 26 member 6

2

0

High-throughput

0.580

High

1428521

ELOV4
Very long chain fatty acid elongase 4

2

0

High-throughput

0.580

High

1430296

TM222
Transmembrane protein 222

2

0

High-throughput

0.580

High

1434962

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.580

High

411108

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

2

High-throughput

0.576

High

337919

CLD7
Claudin-7

2

1

High-throughput

0.553

High

1109093

AQP6
Aquaporin-6

2

2

High-throughput

0.553

High

641699

ERBB3
Receptor tyrosine-protein kinase erbB-3

2

2

High-throughput

0.526

High

1145792

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

2

High-throughput

0.526

High

459794

PROF1
Profilin-1

1

0

High-throughput

0.518

High

481409

HMGB1
High mobility group protein B1

1

0

High-throughput

0.518

High

702424

PEX2
Peroxisome biogenesis factor 2

1

0

High-throughput

0.518

High

895506

SPB9
Serpin B9

1

0

High-throughput

0.518

High

900216

FXR1
RNA-binding protein FXR1

1

0

High-throughput

0.518

High

955739

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.518

High

963033

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.518

High

991762

DYL1
Dynein light chain 1, cytoplasmic

1

0

High-throughput

0.518

High

1008671

CRADD
Death domain-containing protein CRADD

1

0

High-throughput

0.518

High

1142468

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.518

High

1454157

TM63C
Osmosensitive cation channel TMEM63C

1

0

High-throughput

0.513

High

628028

ANXA7
Annexin A7

1

1

High-throughput

0.508

High

974216

RUXG
Small nuclear ribonucleoprotein G

1

1

High-throughput

0.494

High

1416614

BTBD2
BTB/POZ domain-containing protein 2

1

1

High-throughput

0.494

High

939663

BID
BH3-interacting domain death agonist

1

0

High-throughput

0.486

High

230464

CREB3
Cyclic AMP-responsive element-binding protein 3

1

2

High-throughput

0.481

High

1152892

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

1

Small-scale

0.481

High

218939

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

403031

ANXA1
Annexin A1

1

1

High-throughput

0.464

High

1152492

T22D1
TSC22 domain family protein 1

1

1

High-throughput

0.464

High

1207788

TMM31
Transmembrane protein 31

1

0

High-throughput

0.460

High

1458889

CLN8
Protein CLN8

1

0

Small-scale

0.460

High

1461199

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.460

High

538090

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

904194

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

1334616

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

880978

MTR1B
Melatonin receptor type 1B

1

1

High-throughput

0.439

High

1122582

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

2

High-throughput

0.437

High

256191

S19A2
Thiamine transporter 1

1

0

High-throughput

0.426

High

936013

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.426

High

1242268

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.426

High

1346828

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

0

High-throughput

0.426

High

1122189

UBP2L
Ubiquitin-associated protein 2-like

1

1

High-throughput

0.407

High

1435902

ZN703
Zinc finger protein 703

1

1

High-throughput

0.407

High

405559

KITH
Thymidine kinase, cytosolic

2

0

High-throughput

0.323

High

189034

TMPS2
Transmembrane protease serine 2

2

0

High-throughput

0.316

High

194763

FFAR2
Free fatty acid receptor 2

2

0

High-throughput

0.316

High

328277

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

2

0

High-throughput

0.316

High

335273

CXB5
Gap junction beta-5 protein

2

0

High-throughput

0.316

High

590358

MUC1
Mucin-1

2

0

High-throughput

0.316

High

622116

CD53
Leukocyte surface antigen CD53

2

0

High-throughput

0.316

High

870087

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

1094881

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1159656

STX1A
Syntaxin-1A

2

0

High-throughput

0.316

High

1186069

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

1207651

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1228659

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

2

0

High-throughput

0.316

High

1234567

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.316

High

1248608

LYPD5
Ly6/PLAUR domain-containing protein 5

2

0

High-throughput

0.316

High

1347220

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

1351726

GP152
Probable G-protein coupled receptor 152

2

0

High-throughput

0.316

High

1382093

T106A
Transmembrane protein 106A

2

0

High-throughput

0.316

High

1388453

MTEF3
Transcription termination factor 3, mitochondrial

2

0

High-throughput

0.316

High

1393280

MS4A3
Membrane-spanning 4-domains subfamily A member 3

2

0

High-throughput

0.316

High

183769

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.282

High

257284

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.282

High

423954

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.282

High

424284

S10A8
Protein S100-A8

1

0

High-throughput

0.282

High

574508

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

0

High-throughput

0.282

High

593242

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.282

High

600392

ZNF24
Zinc finger protein 24

1

0

High-throughput

0.282

High

1405172

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.282

High

621791

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.282

High

639655

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

675201

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

High-throughput

0.282

High

702867

5HT2C
5-hydroxytryptamine receptor 2C

1

0

High-throughput

0.282

High

729145

HNRH3
Heterogeneous nuclear ribonucleoprotein H3

1

0

High-throughput

0.282

High

750495

CSTF2
Cleavage stimulation factor subunit 2

1

0

High-throughput

0.282

High

857201

NSF
Vesicle-fusing ATPase

1

0

High-throughput

0.282

High

892185

ST1E1
Sulfotransferase 1E1

1

0

High-throughput

0.282

High

892319

SPS1
Selenide, water dikinase 1

1

0

High-throughput

0.282

High

902304

RB27A
Ras-related protein Rab-27A

1

0

High-throughput

0.282

High

938543

CCL18
C-C motif chemokine 18

1

0

High-throughput

0.282

High

940510

DPOE2
DNA polymerase epsilon subunit 2

1

0

High-throughput

0.282

High

1091795

PP1R8
Nuclear inhibitor of protein phosphatase 1

1

0

High-throughput

0.282

High

1120105

COX17
Cytochrome c oxidase copper chaperone

1

0

High-throughput

0.282

High

1211525

CELF3
CUGBP Elav-like family member 3

1

0

High-throughput

0.282

High

1364775

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.282

High

1367825

TFG
Protein TFG

1

0

High-throughput

0.282

High

1387994

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.282

High

1397776

HYLS1
Centriolar and ciliogenesis-associated protein HYLS1

1

0

High-throughput

0.282

High

1402924

CK5P2
CDK5 regulatory subunit-associated protein 2

1

0

High-throughput

0.282

High

1413443

NAT9
Alpha/beta-tubulin-N-acetyltransferase 9

1

0

High-throughput

0.282

High

1414357

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

0

High-throughput

0.282

High

1416054

CC106
Coiled-coil domain-containing protein 106

1

0

High-throughput

0.282

High

1431041

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.282

High

1448979

NUA4L
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2

1

0

High-throughput

0.282

High

1461197

PCDA4
Protocadherin alpha-4

1

0

High-throughput

0.282

High

1461198

BAIP2
BAR/IMD domain-containing adapter protein 2

1

0

High-throughput

0.282

High

1461200

KLH20
Kelch-like protein 20

1

0

High-throughput

0.282

High

1461201

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

0

High-throughput

0.282

High

1351541

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.269

Low

389897

TTHY
Transthyretin

1

0

High-throughput

0.265

Low

665291

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.265

Low

891874

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.265

Low

933963

NR1H2
Oxysterols receptor LXR-beta

1

0

High-throughput

0.265

Low

1103739

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

0

High-throughput

0.265

Low

1460901

KS6A6
Ribosomal protein S6 kinase alpha-6

1

0

High-throughput

0.265

Low

386351

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

1187599

AR13B
ADP-ribosylation factor-like protein 13B

1

0

High-throughput

0.251

Low

162053

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

0

High-throughput

0.249

Low

947309

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

731816

FCG2B
Low affinity immunoglobulin gamma Fc region receptor II-b

1

0

High-throughput

0.238

Low

1449645

ZF64B
Zinc finger protein 64

1

0

High-throughput

0.238

Low

775368

FUS
RNA-binding protein FUS

1

0

High-throughput

0.232

Low

829589

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

1180756

LETM2
LETM1 domain-containing protein LETM2, mitochondrial

1

0

High-throughput

0.232

Low

1458406

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025