Protein: ORML2
ORM1-like protein 2 (Adoplin-2)

Gene: ORML2, ORMDL2
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q53FV1

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006672 - ceramide metabolic process
GO:0017059 - serine palmitoyltransferase complex
GO:0030148 - sphingolipid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

184850

SPTC1
Serine palmitoyltransferase 1

1

8

High-throughput

0.691

High

733498

GP183
G-protein coupled receptor 183

3

1

High-throughput

0.609

High

360004

NB5R3
NADH-cytochrome b5 reductase 3

2

1

High-throughput

0.606

High

1142837

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

2

High-throughput

0.606

High

1198928

RETR3
Reticulophagy regulator 3

2

1

High-throughput

0.606

High

1198931

EMC5
ER membrane protein complex subunit 5

2

1

High-throughput

0.606

High

1198937

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.606

High

1198941

ZDH15
Palmitoyltransferase ZDHHC15

2

1

High-throughput

0.606

High

1198945

ELOV4
Very long chain fatty acid elongase 4

2

1

High-throughput

0.606

High

418179

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

2

0

High-throughput

0.602

High

1198932

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.580

High

1198943

TACAN
Transmembrane protein 120A

2

0

High-throughput

0.580

High

1198956

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

879787

NPY2R
Neuropeptide Y receptor type 2

2

1

High-throughput

0.574

High

1198930

S22A9
Organic anion transporter 7

2

6

High-throughput

0.574

High

1198934

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

1

High-throughput

0.574

High

1198936

SC5A5
Sodium/iodide cotransporter

2

3

High-throughput

0.574

High

549782

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.553

High

1108906

AQP6
Aquaporin-6

2

5

High-throughput

0.553

High

1134102

NTCP
Hepatic sodium/bile acid cotransporter

2

3

High-throughput

0.553

High

1198940

F210B
Protein FAM210B, mitochondrial

2

1

High-throughput

0.553

High

1198952

SCN3B
Sodium channel regulatory subunit beta-3

2

1

High-throughput

0.553

High

1198938

BSCL2
Seipin

1

1

High-throughput

0.536

High

1198944

S26A6
Solute carrier family 26 member 6

1

1

High-throughput

0.536

High

1198953

GABR1
Gamma-aminobutyric acid type B receptor subunit 1

1

1

High-throughput

0.536

High

1198957

CBPQ
Carboxypeptidase Q

1

0

High-throughput

0.513

High

832406

OPRX
Nociceptin receptor

1

2

High-throughput

0.489

High

880146

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.489

High

1053000

VMAT2
Synaptic vesicular amine transporter

1

2

High-throughput

0.489

High

1198939

CREL1
Protein disulfide isomerase CRELD1

1

2

High-throughput

0.489

High

1198946

S22A4
Solute carrier family 22 member 4

1

6

High-throughput

0.489

High

1198948

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

1198955

SC5A6
Sodium-dependent multivitamin transporter

1

3

High-throughput

0.489

High

1198951

SAR1A
Small COPII coat GTPase SAR1A

1

2

High-throughput

0.481

High

1198954

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

3

High-throughput

0.481

High

1102397

BIK
Bcl-2-interacting killer

1

1

High-throughput

0.439

High

1198947

IF3M
Translation initiation factor IF-3, mitochondrial

1

2

High-throughput

0.439

High

1198949

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

1

High-throughput

0.439

High

1198950

S35C2
Solute carrier family 35 member C2

1

2

High-throughput

0.439

High

1198925

TECT3
Tectonic-3

1

1

High-throughput

0.437

High

1198927

S39A4
Zinc transporter ZIP4

1

1

High-throughput

0.437

High

1198929

GOLI
E3 ubiquitin-protein ligase RNF130

1

2

High-throughput

0.437

High

1198935

ESR2
Estrogen receptor beta

1

1

High-throughput

0.437

High

1198933

S7A14
Solute carrier family 7 member 14

1

2

High-throughput

0.407

High

1198958

SO1B1
Solute carrier organic anion transporter family member 1B1

2

0

High-throughput

0.328

High

870045

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

870721

CXA8
Gap junction alpha-8 protein

2

0

High-throughput

0.316

High

883418

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

0

High-throughput

0.316

High

920452

DAPK1
Death-associated protein kinase 1

1

0

High-throughput

0.279

Low

617525

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.279

Low

718697

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.251

Low

1198924

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

293786

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

820660

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.249

Low

942660

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.249

Low

1198942

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1198926

NPAL3
NIPA-like protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025