Protein: SFXN5
Sideroflexin-5

Gene: SFXN5
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q8TD22

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006865 - amino acid transport
GO:0015075 - monoatomic ion transmembrane transporter activity
GO:0015137 - citrate transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

926809

VMAT1
Chromaffin granule amine transporter

4

3

High-throughput

0.630

High

1350636

S39A9
Zinc transporter ZIP9

2

1

High-throughput

0.628

High

851075

LPAR6
Lysophosphatidic acid receptor 6

3

7

High-throughput

0.609

High

690319

STOM
Stomatin

2

4

High-throughput

0.606

High

1350578

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

3

2

High-throughput

0.604

High

1350633

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

2

0

High-throughput

0.602

High

354367

TOM40
Mitochondrial import receptor subunit TOM40 homolog

2

2

High-throughput

0.601

High

956949

CXCR4
C-X-C chemokine receptor type 4

2

7

High-throughput

0.601

High

406913

MAS
Proto-oncogene Mas

2

8

High-throughput

0.574

High

562260

LAMP2
Lysosome-associated membrane glycoprotein 2

2

3

High-throughput

0.574

High

771187

APJ
Apelin receptor

2

7

High-throughput

0.574

High

854558

S15A1
Solute carrier family 15 member 1

2

1

High-throughput

0.574

High

1196206

S22A6
Solute carrier family 22 member 6

2

2

High-throughput

0.574

High

1249771

TM108
Transmembrane protein 108

2

1

High-throughput

0.574

High

1350624

GLMP
Glycosylated lysosomal membrane protein

2

1

High-throughput

0.574

High

1350626

SC5A5
Sodium/iodide cotransporter

2

1

High-throughput

0.574

High

1108983

AQP6
Aquaporin-6

2

3

High-throughput

0.553

High

1142896

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.553

High

1350628

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

2

High-throughput

0.553

High

182685

GP182
G-protein coupled receptor 182

2

11

High-throughput

0.549

High

754074

CD80
T-lymphocyte activation antigen CD80

2

2

High-throughput

0.549

High

1177172

MICB
MHC class I polypeptide-related sequence B

2

1

High-throughput

0.549

High

880178

PTH2R
Parathyroid hormone 2 receptor

1

1

High-throughput

0.536

High

1350632

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.536

High

221463

OX2R
Orexin receptor type 2

1

4

High-throughput

0.489

High

565674

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.489

High

688598

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

5

High-throughput

0.489

High

702816

5HT2C
5-hydroxytryptamine receptor 2C

1

1

High-throughput

0.489

High

867652

GPR12
G-protein coupled receptor 12

1

1

High-throughput

0.489

High

1350625

AQP3
Aquaporin-3

1

1

High-throughput

0.489

High

1350639

SC5A6
Sodium-dependent multivitamin transporter

1

1

High-throughput

0.489

High

530116

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

1187794

AL1L2
Mitochondrial 10-formyltetrahydrofolate dehydrogenase

1

1

High-throughput

0.445

High

1350635

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

2

High-throughput

0.445

High

377665

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

2

High-throughput

0.437

High

930339

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

1

1

High-throughput

0.437

High

1350627

RAB24
Ras-related protein Rab-24

1

0

High-throughput

0.426

High

1350631

MGME1
Mitochondrial genome maintenance exonuclease 1

1

0

High-throughput

0.426

High

1350637

NB5R1
NADH-cytochrome b5 reductase 1

1

0

High-throughput

0.426

High

248919

GSDME
Gasdermin-E

1

1

High-throughput

0.407

High

469518

SYPH
Synaptophysin

1

2

High-throughput

0.407

High

669348

ACKR3
Atypical chemokine receptor 3

1

12

High-throughput

0.407

High

845085

EAA3
Excitatory amino acid transporter 3

1

3

High-throughput

0.407

High

886109

CXCR3
C-X-C chemokine receptor type 3

1

7

High-throughput

0.407

High

945519

GSDMD
Gasdermin-D

1

1

High-throughput

0.407

High

1350640

NPTN
Neuroplastin

1

6

High-throughput

0.407

High

1350638

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

5

0

High-throughput

0.374

High

378143

TNFA
Tumor necrosis factor

3

0

High-throughput

0.347

High

675092

TNR6
Tumor necrosis factor receptor superfamily member 6

3

0

High-throughput

0.347

High

528699

PPGB
Lysosomal protective protein

3

0

High-throughput

0.345

High

593687

BGAL
Beta-galactosidase

3

0

High-throughput

0.345

High

690591

PON1
Serum paraoxonase/arylesterase 1

2

0

High-throughput

0.328

High

952977

ACTB
Actin, cytoplasmic 1

2

0

High-throughput

0.328

High

1254296

TMPPE
Transmembrane protein with metallophosphoesterase domain

2

0

High-throughput

0.316

High

1328788

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

1350629

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

1350630

APOL2
Apolipoprotein L2

2

0

High-throughput

0.316

High

1293873

VSIG1
V-set and immunoglobulin domain-containing protein 1

2

0

High-throughput

0.313

High

1245890

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

1248535

LCTL
Lactase-like protein

1

0

High-throughput

0.279

Low

646898

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.249

Low

1249622

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.232

Low

1350634

RAB18
Ras-related protein Rab-18

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025