Protein: TIM44
Mitochondrial import inner membrane translocase subunit TIM44 (Inner membrane import site protein 45) (ISP45) (Membrane import machinery protein MIM44) (Mitochondrial protein import protein 1)

Gene: TIM44
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: Q01852

Gene Ontology (top 5):
GO:0001405 - PAM complex, Tim23 associated import motor
GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

746918

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

38

2

Small-scale

0.994

High

811978

TIM17
Mitochondrial import inner membrane translocase subunit TIM17

8

1

Small-scale

0.967

High

510739

HSP77
Import motor subunit, mitochondrial

23

3

Small-scale

0.767

High

844709

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

10

1

Small-scale

0.755

High

1033458

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

7

3

Small-scale

0.741

High

800356

GRPE
GrpE protein homolog, mitochondrial

5

0

Small-scale

0.684

High

881419

TOM22
Mitochondrial import receptor subunit TOM22

4

0

Small-scale

0.648

High

1033449

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

1

Small-scale

0.647

High

918297

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

3

0

Small-scale

0.628

High

1033450

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

2

1

Small-scale

0.584

High

527459

HSP72
Heat shock protein SSA2

2

1

Small-scale

0.571

High

752626

HSP78
Heat shock protein 78, mitochondrial

2

0

High-throughput

0.559

High

358021

CYB2
L-lactate dehydrogenase

2

0

Small-scale

0.547

High

626857

HSP60
Heat shock protein 60, mitochondrial

1

1

Small-scale

0.501

High

918084

JAC1
J-type co-chaperone JAC1, mitochondrial

1

1

Small-scale

0.501

High

524879

HSP71
Heat shock protein SSA1

1

1

Small-scale

0.479

High

613623

ADT2
ADP,ATP carrier protein 2

1

3

Small-scale

0.479

High

671031

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

679982

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

785958

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.479

High

1033451

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

1033455

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

5

Small-scale

0.479

High

1033463

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

364697

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.458

High

382981

RMAR
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.458

High

452956

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

694162

CDC15
Cell division control protein 15

1

0

High-throughput

0.458

High

922873

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

1033452

PDR15
ATP-dependent permease PDR15

1

0

High-throughput

0.458

High

1033454

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

676273

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

742202

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

816358

HSP7E
Heat shock protein SSC3, mitochondrial

1

3

High-throughput

0.445

High

843138

MDJ2
Mitochondrial DnaJ homolog 2

1

3

Small-scale

0.445

High

707934

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

808540

TEM1
Protein TEM1

1

1

High-throughput

0.437

High

816125

SIT1
Siderophore iron transporter 1

1

1

High-throughput

0.437

High

923856

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

1026802

CDC14
Tyrosine-protein phosphatase CDC14

1

1

High-throughput

0.437

High

1033459

ENB1
Siderophore iron transporter ENB1

1

1

High-throughput

0.437

High

359320

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.426

High

763004

SPT7
SAGA complex subunit SPT7

1

0

High-throughput

0.426

High

819543

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.426

High

409772

RL24A
Large ribosomal subunit protein eL24A

1

0

High-throughput

0.279

Low

747529

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.279

Low

893326

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.279

Low

594522

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

736038

SP110
Spindle pole body component 110

1

0

High-throughput

0.249

Low

739729

SPT16
FACT complex subunit SPT16

1

0

High-throughput

0.249

Low

797777

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

812576

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

826753

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

1033453

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

1033456

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

1033457

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

1033462

UBX3
UBX domain-containing protein 3

1

0

High-throughput

0.238

Low

655505

RS3A2
Small ribosomal subunit protein eS1B

1

0

High-throughput

0.232

Low

807258

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.232

Low

885064

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.232

Low

924702

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low

1033460

HFI1
SAGA complex subunit HFI1

1

0

High-throughput

0.232

Low

1033461

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025