Protein: DBF4
DDK kinase regulatory subunit DBF4 (Dumbbell forming protein 4)

Gene: DBF4
Organism: Saccharomyces cerevisiae S288C
Interactions: 53
UniProt ID: P32325

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0001100 - negative regulation of exit from mitosis
GO:0001934 - positive regulation of protein phosphorylation
GO:0003688 - DNA replication origin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

412535

CDC7
Cell division control protein 7

29

3

Small-scale

0.993

High

605939

RAD53
Serine/threonine-protein kinase RAD53

13

0

Small-scale

0.931

High

687524

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

7

0

Small-scale

0.923

High

339504

CDK1
Cyclin-dependent kinase 1

2

0

Small-scale

0.771

High

667550

MCM2
DNA replication licensing factor MCM2

7

3

Small-scale

0.749

High

687538

FKH1
Fork head protein homolog 1

1

1

Small-scale

0.740

High

687522

DBF4
DDK kinase regulatory subunit DBF4

4

0

Small-scale

0.652

High

687527

ORC2
Origin recognition complex subunit 2

3

0

Small-scale

0.632

High

687544

MCM6
DNA replication licensing factor MCM6

2

3

Small-scale

0.625

High

687541

FKH2
Fork head protein homolog 2

1

1

Small-scale

0.621

High

687523

MCM10
Minichromosome maintenance protein 10

2

1

Small-scale

0.602

High

687549

ORC3
Origin recognition complex subunit 3

2

0

Small-scale

0.593

High

675508

MCM4
DNA replication licensing factor MCM4

2

4

Small-scale

0.585

High

668151

RIF1
Telomere length regulator protein RIF1

2

0

Small-scale

0.559

High

687539

ULP2
Ubiquitin-like-specific protease 2

1

0

Small-scale

0.529

High

687543

ORC5
Origin recognition complex subunit 5

1

0

Small-scale

0.529

High

687554

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.518

High

687545

SLD3
DNA replication regulator SLD3

1

0

Small-scale

0.504

High

622149

MCM3
DNA replication licensing factor MCM3

1

3

Small-scale

0.501

High

667835

MCM5
Minichromosome maintenance protein 5

1

3

Small-scale

0.501

High

687530

MCM7
DNA replication licensing factor MCM7

1

1

Small-scale

0.501

High

392342

H2A2
Histone H2A.2

1

0

High-throughput

0.493

High

687536

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.493

High

687550

H3
Histone H3

1

0

High-throughput

0.493

High

565147

CBF1
Centromere-binding protein 1

1

0

Small-scale

0.480

High

640832

CDC20
APC/C activator protein CDC20

1

0

Small-scale

0.480

High

687542

COM1
DNA endonuclease SAE2

1

0

Small-scale

0.480

High

687547

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

Small-scale

0.480

High

687551

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.480

High

687552

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

Small-scale

0.480

High

687555

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.480

High

687558

CENPI
Inner kinetochore subunit CTF3

1

0

Small-scale

0.480

High

687533

RT107
Regulator of Ty1 transposition protein 107

1

1

Small-scale

0.479

High

687546

TOF1
Topoisomerase 1-associated factor 1

1

1

Small-scale

0.479

High

687526

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

Small-scale

0.460

High

687529

MSA2
Putative transcriptional activator MSA2

1

0

Small-scale

0.460

High

687532

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.460

High

687557

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

Small-scale

0.460

High

661587

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

687531

MMS4
Crossover junction endonuclease MMS4

1

0

Small-scale

0.458

High

687534

REV7
DNA polymerase zeta processivity subunit

1

0

Small-scale

0.458

High

687540

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

687556

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

687525

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.445

High

490601

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.426

High

510564

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

687548

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

687537

RPN3
26S proteasome regulatory subunit RPN3

1

0

High-throughput

0.269

Low

687553

ESC1
Silent chromatin protein ESC1

1

0

Small-scale

0.261

Low

687535

STN1
Protein STN1

1

0

Small-scale

0.251

Low

687528

ATO2
Ammonia transport outward protein 2

1

0

High-throughput

0.249

Low

655796

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024