Protein: COX5A
Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va)

Gene: COX5A
Organism: Saccharomyces cerevisiae S288C
Interactions: 60
UniProt ID: P00424

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005758 - mitochondrial intermembrane space
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0016491 - oxidoreductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

360762

COX4
Cytochrome c oxidase subunit 4, mitochondrial

5

1

Small-scale

0.912

High

360768

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

3

3

Small-scale

0.817

High

360304

COX1
Cytochrome c oxidase subunit 1

2

1

Small-scale

0.754

High

360760

COX6
Cytochrome c oxidase subunit 6, mitochondrial

2

1

High-throughput

0.754

High

360621

COX2
Cytochrome c oxidase subunit 2

2

1

Small-scale

0.737

High

360767

COX9
Cytochrome c oxidase subunit 9, mitochondrial

4

0

High-throughput

0.649

High

360785

MIC60
MICOS complex subunit MIC60

3

1

High-throughput

0.640

High

357740

QCR6
Cytochrome b-c1 complex subunit 6, mitochondrial

3

1

Small-scale

0.633

High

360802

SHY1
Cytochrome oxidase assembly protein SHY1

3

0

Small-scale

0.628

High

360769

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

3

High-throughput

0.618

High

360812

COA3
Cytochrome c oxidase assembly factor 3, mitochondrial

2

1

Small-scale

0.611

High

360775

ADT2
ADP,ATP carrier protein 2

2

0

Small-scale

0.585

High

360764

VDAC1
Non-selective voltage-gated ion channel 1

2

1

High-throughput

0.584

High

360781

COX13
Cytochrome c oxidase subunit 13, mitochondrial

2

1

High-throughput

0.584

High

360803

RCF2
Respiratory supercomplex factor 2, mitochondrial

2

1

Small-scale

0.584

High

360770

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

2

1

Small-scale

0.571

High

360771

QCR8
Cytochrome b-c1 complex subunit 8, mitochondrial

2

1

Small-scale

0.571

High

360766

CY1
Cytochrome c1, heme protein, mitochondrial

2

0

Small-scale

0.547

High

360734

COX3
Cytochrome c oxidase subunit 3

1

0

Small-scale

0.480

High

357790

QCR7
Cytochrome b-c1 complex subunit 7, mitochondrial

1

1

High-throughput

0.479

High

360763

COX8
Cytochrome c oxidase subunit 8, mitochondrial

1

1

High-throughput

0.479

High

360765

ATPF
ATP synthase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

360782

DLD1
D-lactate dehydrogenase [cytochrome] 1, mitochondrial

1

1

High-throughput

0.479

High

360787

QCR10
Cytochrome b-c1 complex subunit 10, mitochondrial

1

1

High-throughput

0.479

High

360789

COX14
Cytochrome c oxidase assembly protein COX14

1

1

Small-scale

0.479

High

360790

AFG3
Mitochondrial inner membrane m-AAA protease component YTA10

1

1

High-throughput

0.479

High

360792

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

1

High-throughput

0.479

High

360794

YTA12
Mitochondrial inner membrane m-AAA protease component YTA12

1

1

High-throughput

0.479

High

360797

PHB1
Prohibitin-1

1

3

High-throughput

0.479

High

360799

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

360800

PHB2
Prohibitin-2

1

3

High-throughput

0.479

High

360806

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

1

High-throughput

0.479

High

360811

COX26
Cytochrome c oxidase subunit 26, mitochondrial

1

1

Small-scale

0.479

High

360759

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

0

High-throughput

0.458

High

360761

ATP6
ATP synthase subunit a

1

0

Small-scale

0.458

High

360772

ATPO
ATP synthase subunit 5, mitochondrial

1

0

High-throughput

0.458

High

360773

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

360774

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

360776

PMA2
Plasma membrane ATPase 2

1

0

High-throughput

0.458

High

360777

QCR9
Cytochrome b-c1 complex subunit 9, mitochondrial

1

0

High-throughput

0.458

High

360778

MSS51
Protein MSS51, mitochondrial

1

0

Small-scale

0.458

High

360783

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

360784

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

360786

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.458

High

360788

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

360791

COX15
Heme A synthase COX15

1

0

Small-scale

0.458

High

360795

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.458

High

360796

COA1
Cytochrome c oxidase assembly factor 1

1

0

Small-scale

0.458

High

360798

COX16
Cytochrome c oxidase assembly protein COX16, mitochondrial

1

0

Small-scale

0.458

High

360801

MDM34
Mitochondrial distribution and morphology protein 34

1

0

Small-scale

0.458

High

360805

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

360807

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

Small-scale

0.458

High

360808

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.458

High

360810

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

360804

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

360780

HSP7F
Heat shock protein homolog SSE1

1

1

High-throughput

0.407

High

360793

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.407

High

360809

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.269

Low

360779

MKK1
MAP kinase kinase MKK1/SSP32

1

0

High-throughput

0.261

Low

64204

YP010
UPF0495 protein YPR010C-A

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025