Protein: PUR8
Adenylosuccinate lyase (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase)

Gene: PUR8, ADE13
Organism: Saccharomyces cerevisiae S288C
Interactions: 41
UniProt ID: Q05911

Gene Ontology (top 5):
GO:0004018 - N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity
GO:0005829 - cytosol
GO:0006164 - purine nucleotide biosynthetic process
GO:0006189 - 'de novo' IMP biosynthetic process
GO:0044208 - 'de novo' AMP biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1052801

PUR8
Adenylosuccinate lyase

1

14

High-throughput

0.656

High

850209

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

728717

ACBP
Acyl-CoA-binding protein

1

2

High-throughput

0.515

High

916428

SEH1
Nucleoporin SEH1

1

1

High-throughput

0.489

High

359071

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.479

High

365696

PGK
Phosphoglycerate kinase

1

1

High-throughput

0.479

High

367812

ENO1
Enolase 1

1

3

High-throughput

0.479

High

368059

ENO2
Enolase 2

1

3

High-throughput

0.479

High

368484

TPIS
Triosephosphate isomerase

1

1

High-throughput

0.479

High

368756

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.479

High

393345

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.479

High

546308

SSB1
Ribosome-associated molecular chaperone SSB1

1

6

High-throughput

0.479

High

555155

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.479

High

580082

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

671133

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

737388

EF1B
Elongation factor 1-beta

1

1

High-throughput

0.479

High

812664

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

416478

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

439431

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

454352

PHO2
Regulatory protein PHO2

1

0

Small-scale

0.458

High

572650

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.458

High

527699

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

819820

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

708207

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

795221

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

807060

CH10
10 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.437

High

815237

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

918691

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.437

High

1052802

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.437

High

1052805

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

1052806

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

1052807

DBP10
ATP-dependent RNA helicase DBP10

1

1

High-throughput

0.437

High

597279

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.407

High

438490

EIF3B
Eukaryotic translation initiation factor 3 subunit B

2

0

High-throughput

0.307

High

794302

PPS1
Dual specificity protein phosphatase PPS1

1

0

High-throughput

0.269

Low

454489

PHO4
Phosphate system positive regulatory protein PHO4

1

0

Small-scale

0.249

Low

643278

BAS1
Myb-like DNA-binding protein BAS1

1

0

Small-scale

0.249

Low

1052803

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1052804

ZEO1
Protein ZEO1

1

0

High-throughput

0.249

Low

634283

NUP1
Nucleoporin NUP1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025