Protein: DNPEP
Aspartyl aminopeptidase 4 (EC 3.4.11.21)

Gene: DNPEP, APE4
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P38821

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0000328 - fungal-type vacuole lumen
GO:0004177 - aminopeptidase activity
GO:0005737 - cytoplasm
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805371

DNPEP
Aspartyl aminopeptidase 4

3

4

Small-scale

0.841

High

576965

AMPL
Vacuolar aminopeptidase 1

2

4

High-throughput

0.775

High

763530

ATG19
Autophagy-related protein 19

4

2

Small-scale

0.700

High

523880

HSP71
Heat shock protein SSA1

2

2

High-throughput

0.601

High

795333

ATG8
Autophagy-related protein 8

2

2

Small-scale

0.584

High

526641

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

805381

IMA1
Importin subunit alpha

1

1

High-throughput

0.508

High

805373

TEM1
Protein TEM1

1

3

High-throughput

0.494

High

734664

IMB3
Importin subunit beta-3

1

0

High-throughput

0.486

High

798440

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.486

High

805376

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.486

High

805377

MAD2
Mitotic spindle checkpoint component MAD2

1

0

High-throughput

0.486

High

805379

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.486

High

805383

POC3
Proteasome chaperone 3

1

0

High-throughput

0.486

High

748741

YPT7
Ypt/Rab-type GTPase YPT7

1

1

High-throughput

0.479

High

760582

TSA1
Peroxiredoxin TSA1

1

1

High-throughput

0.479

High

738640

EI2BB
Translation initiation factor eIF2B subunit beta

1

1

High-throughput

0.464

High

763319

TAF14
Transcription initiation factor TFIID subunit 14

1

1

High-throughput

0.464

High

805372

KOG1
Target of rapamycin complex 1 subunit KOG1

1

0

High-throughput

0.460

High

359215

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

High-throughput

0.458

High

365039

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.458

High

368441

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

727009

HS104
Heat shock protein 104

1

0

High-throughput

0.458

High

790197

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.458

High

792346

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.458

High

544801

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

741538

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

805375

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

368661

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.437

High

679655

CDC48
Cell division control protein 48

1

1

High-throughput

0.437

High

805382

TRS31
Trafficking protein particle complex subunit 31

1

1

High-throughput

0.437

High

394535

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

744609

TFB1
General transcription and DNA repair factor IIH subunit TFB1

1

1

High-throughput

0.417

High

797104

CENPL
Inner kinetochore subunit IML3

2

0

High-throughput

0.310

High

737525

EUG1
Protein disulfide-isomerase EUG1

1

0

High-throughput

0.265

Low

805378

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

High-throughput

0.265

Low

805384

YIG1
Protein YIG1

1

0

High-throughput

0.265

Low

794975

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

805380

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

0

High-throughput

0.249

Low

805385

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

805374

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025