Protein: CDC15
Cell division control protein 15 (EC 2.7.11.1)

Gene: CDC15
Organism: Saccharomyces cerevisiae S288C
Interactions: 109
UniProt ID: P27636

Gene Ontology (top 5):
GO:0000281 - mitotic cytokinesis
GO:0000922 - spindle pole
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

694135

TEM1
Protein TEM1

8

13

Small-scale

0.971

High

694158

CDC14
Tyrosine-protein phosphatase CDC14

3

5

Small-scale

0.845

High

645883

DBF2
Cell cycle protein kinase DBF2

2

20

Small-scale

0.806

High

392339

HSP82
ATP-dependent molecular chaperone HSP82

2

20

High-throughput

0.786

High

694105

CDC15
Cell division control protein 15

2

18

Small-scale

0.768

High

694109

NUD1
Protein NUD1

2

12

Small-scale

0.687

High

437888

KAPC
cAMP-dependent protein kinase type 3

1

14

High-throughput

0.647

High

642338

MCK1
Protein kinase MCK1

1

20

High-throughput

0.647

High

671935

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

17

High-throughput

0.647

High

672183

KIN82
Serine/threonine-protein kinase KIN82

1

17

High-throughput

0.647

High

673729

SSK22
Serine/threonine-protein kinase SSK22

1

18

High-throughput

0.647

High

694108

PSK1
Serine/threonine-protein kinase PSK1

1

18

High-throughput

0.647

High

694111

KNS1
Dual specificity protein kinase KNS1

1

17

High-throughput

0.647

High

694112

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

18

High-throughput

0.647

High

694115

MKK1
MAP kinase kinase MKK1/SSP32

1

17

High-throughput

0.647

High

694116

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

18

High-throughput

0.647

High

694130

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

20

High-throughput

0.647

High

694136

DUN1
DNA damage response protein kinase DUN1

1

17

High-throughput

0.647

High

694147

PRK1
Actin-regulating kinase PRK1

1

18

High-throughput

0.647

High

694149

IKS1
Probable serine/threonine-protein kinase IKS1

1

17

High-throughput

0.647

High

694151

CLA4
Serine/threonine-protein kinase CLA4

1

17

High-throughput

0.647

High

694153

FMP48
Probable serine/threonine-protein kinase FMP48

1

18

High-throughput

0.647

High

694157

MPS1
Serine/threonine-protein kinase MPS1

1

17

High-throughput

0.647

High

694161

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

17

High-throughput

0.647

High

694163

KIN4
Serine/threonine-protein kinase KIN4

1

18

High-throughput

0.647

High

694167

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

19

High-throughput

0.647

High

694175

HRK1
Serine/threonine-protein kinase HRK1

1

18

High-throughput

0.647

High

694177

PRR2
Serine/threonine-protein kinase PRR2

1

19

High-throughput

0.647

High

694180

SKS1
Serine/threonine-protein kinase SKS1

1

19

High-throughput

0.647

High

364376

CDK1
Cyclin-dependent kinase 1

1

10

High-throughput

0.618

High

470110

SPS1
Sporulation-specific protein 1

1

19

Small-scale

0.618

High

656380

KC11
Casein kinase I homolog 1

1

18

High-throughput

0.618

High

656709

KC12
Casein kinase I homolog 2

1

19

High-throughput

0.618

High

694114

HOG1
Mitogen-activated protein kinase HOG1

1

20

High-throughput

0.618

High

694117

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

11

High-throughput

0.618

High

694160

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

20

High-throughput

0.618

High

694168

STE20
Serine/threonine-protein kinase STE20

1

16

Small-scale

0.618

High

694178

ARP8
Actin-like protein ARP8

1

8

High-throughput

0.618

High

694143

SSB2
Ribosome-associated molecular chaperone SSB2

2

10

High-throughput

0.552

High

603421

VATA
V-type proton ATPase catalytic subunit A

1

7

High-throughput

0.536

High

633440

PP11
Serine/threonine-protein phosphatase PP1-1

1

20

High-throughput

0.536

High

694107

XPO1
Exportin-1

1

11

High-throughput

0.536

High

694132

DBP8
ATP-dependent RNA helicase DBP8

1

7

High-throughput

0.536

High

694156

ATG4
Cysteine protease ATG4

1

1

High-throughput

0.536

High

694154

RBG2
Ribosome-interacting GTPase 2

1

2

High-throughput

0.515

High

673346

GLRX1
Glutaredoxin-1

1

2

High-throughput

0.501

High

692483

GYS2
Glycogen [starch] synthase isoform 2

1

1

High-throughput

0.501

High

694146

MOB1
DBF2 kinase activator protein MOB1

1

14

Small-scale

0.501

High

694148

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

1

High-throughput

0.501

High

394301

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.500

High

598970

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

3

High-throughput

0.500

High

679441

CDC48
Cell division control protein 48

1

6

High-throughput

0.500

High

694121

BMH2
Protein BMH2

1

18

High-throughput

0.500

High

694142

IMB4
Importin subunit beta-4

1

8

High-throughput

0.500

High

694133

KOG1
Target of rapamycin complex 1 subunit KOG1

1

19

High-throughput

0.481

High

694128

APD1
Actin patches distal protein 1

1

0

High-throughput

0.480

High

694140

SYPM
Probable proline--tRNA ligase, mitochondrial

1

0

High-throughput

0.480

High

694166

ROD1
Protein ROD1

1

0

High-throughput

0.480

High

438634

SC160
Protein SCP160

1

6

High-throughput

0.479

High

664414

MCM3
DNA replication licensing factor MCM3

1

5

High-throughput

0.479

High

693214

URK1
Uridine kinase

1

2

High-throughput

0.479

High

694106

MCM5
Minichromosome maintenance protein 5

1

2

High-throughput

0.479

High

694122

SKI2
Antiviral helicase SKI2

1

10

High-throughput

0.479

High

694123

DOA1
Protein DOA1

1

16

High-throughput

0.479

High

694124

SN114
Pre-mRNA-splicing factor SNU114

1

3

High-throughput

0.479

High

694125

DBP7
ATP-dependent RNA helicase DBP7

1

7

High-throughput

0.479

High

694139

RV167
Reduced viability upon starvation protein 167

1

5

High-throughput

0.479

High

694141

GLE2
mRNA export factor GLE2

1

2

Small-scale

0.479

High

694145

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.479

High

694150

MTR4
ATP-dependent RNA helicase DOB1

1

10

High-throughput

0.479

High

694152

MSN5
Protein MSN5

1

10

High-throughput

0.479

High

694155

CNM67
Chaotic nuclear migration protein 67

1

1

High-throughput

0.479

High

694159

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

10

High-throughput

0.479

High

627750

TYR1
Prephenate dehydrogenase [NADP(+)]

1

0

High-throughput

0.458

High

678073

SYP1
Suppressor of yeast profilin deletion

1

0

High-throughput

0.458

High

694120

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.458

High

694162

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.458

High

694170

DOP1
Protein DOP1

1

0

High-throughput

0.458

High

694172

ARMT1
Damage-control phosphatase YMR027W

1

0

High-throughput

0.458

High

694174

GSHB
Glutathione synthetase GSH2

1

0

High-throughput

0.458

High

694179

PAA1
Polyamine N-acetyltransferase 1

1

0

High-throughput

0.458

High

381915

H4
Histone H4

1

2

Small-scale

0.457

High

383095

RLA4
Large ribosomal subunit protein P2B

1

2

High-throughput

0.457

High

401913

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.457

High

694164

UBC7
Ubiquitin-conjugating enzyme E2 7

1

4

High-throughput

0.457

High

510254

HSP77
Import motor subunit, mitochondrial

1

15

High-throughput

0.445

High

526073

HSP72
Heat shock protein SSA2

1

9

High-throughput

0.445

High

544027

SSB1
Ribosome-associated molecular chaperone SSB1

1

10

High-throughput

0.445

High

694118

HSP7F
Heat shock protein homolog SSE1

1

15

High-throughput

0.445

High

693168

PHO91
Low-affinity phosphate transporter PHO91

1

1

High-throughput

0.437

High

694126

NU133
Nucleoporin NUP133

1

2

High-throughput

0.437

High

694119

CDC13
Cell division control protein 13

1

0

High-throughput

0.269

Low

619152

IF5A2
Eukaryotic translation initiation factor 5A-2

1

0

High-throughput

0.261

Low

694129

TOS1
Probable circularly permuted 1,3-beta-glucanase TOS1

1

0

High-throughput

0.261

Low

694169

YMD7
Uncharacterized protein YML037C

1

0

High-throughput

0.261

Low

694176

YIG1
Protein YIG1

1

0

High-throughput

0.261

Low

94541

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

694110

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.249

Low

694113

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.249

Low

694127

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

694131

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

0

High-throughput

0.249

Low

694134

UTP9
U3 small nucleolar RNA-associated protein 9

1

0

High-throughput

0.249

Low

694137

DSS1
Exoribonuclease II, mitochondrial

1

0

High-throughput

0.249

Low

694138

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

694144

NUP82
Nucleoporin NUP82

1

0

High-throughput

0.249

Low

694165

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.249

Low

694171

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

694173

RRP45
Exosome complex component RRP45

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025