Protein: LGE1
Transcriptional regulatory protein LGE1 (Large cells protein 1)

Gene: LGE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 148
UniProt ID: Q02796

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0006279 - premeiotic DNA replication
GO:0006325 - chromatin organization
GO:0008361 - regulation of cell size
GO:0140693 - molecular condensate scaffold activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038824

BRE1
E3 ubiquitin-protein ligase BRE1

7

0

Small-scale

0.713

High

1038813

LGE1
Transcriptional regulatory protein LGE1

2

0

High-throughput

0.699

High

664342

SSD1
Protein SSD1

3

0

High-throughput

0.606

High

924415

CBK1
Serine/threonine-protein kinase CBK1

3

0

High-throughput

0.606

High

646078

KIN3
Serine/threonine-protein kinase KIN3

2

1

High-throughput

0.571

High

672028

MSH3
DNA mismatch repair protein MSH3

2

2

High-throughput

0.571

High

682936

MSH2
DNA mismatch repair protein MSH2

2

2

High-throughput

0.571

High

801900

KSP1
Serine/threonine-protein kinase KSP1

2

1

High-throughput

0.571

High

806215

SPC97
Spindle pole body component SPC97

2

1

High-throughput

0.571

High

921074

SPC98
Spindle pole body component SPC98

2

1

High-throughput

0.571

High

1038819

MSH6
DNA mismatch repair protein MSH6

2

2

High-throughput

0.571

High

382296

H4
Histone H4

2

0

High-throughput

0.547

High

448468

RAD52
DNA repair and recombination protein RAD52

2

0

High-throughput

0.547

High

672781

SNT1
Probable DNA-binding protein SNT1

2

0

High-throughput

0.547

High

679994

CDC48
Cell division control protein 48

2

0

High-throughput

0.547

High

694626

SPT5
Transcription elongation factor SPT5

2

0

High-throughput

0.547

High

736040

SP110
Spindle pole body component 110

2

0

High-throughput

0.547

High

753036

SPC29
Spindle pole component 29

2

0

High-throughput

0.547

High

762865

TOR1
Serine/threonine-protein kinase TOR1

2

0

High-throughput

0.547

High

780981

SPC42
Spindle pole body component SPC42

2

0

High-throughput

0.547

High

1026808

CDC14
Tyrosine-protein phosphatase CDC14

2

0

High-throughput

0.547

High

811274

RGA1
Rho-type GTPase-activating protein 1

2

1

High-throughput

0.521

High

864316

NET1
Nucleolar protein NET1

2

1

High-throughput

0.521

High

1033854

KIN4
Serine/threonine-protein kinase KIN4

2

1

High-throughput

0.521

High

1038815

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

2

1

High-throughput

0.521

High

722191

XPO1
Exportin-1

1

0

High-throughput

0.513

High

794207

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.493

High

444607

DED1
ATP-dependent RNA helicase DED1

1

2

High-throughput

0.479

High

666534

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

597251

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

750759

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.460

High

1038823

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

393210

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.458

High

435303

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

449000

TOP2
DNA topoisomerase 2

1

0

High-throughput

0.458

High

534303

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

0

High-throughput

0.458

High

594529

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

644975

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

707966

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

735128

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

792205

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

826767

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

925303

BOP3
Protein BOP3

1

0

High-throughput

0.458

High

1028601

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1031033

NOP3
Serine/arginine

1

0

High-throughput

0.458

High

524920

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527494

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

666598

DBP1
ATP-dependent RNA helicase DBP1

1

2

High-throughput

0.445

High

742234

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

1038821

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

584266

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

3

High-throughput

0.437

High

366835

IPYR
Inorganic pyrophosphatase

1

0

High-throughput

0.426

High

419846

H2A2
Histone H2A.2

1

0

High-throughput

0.426

High

438544

UBC2
Ubiquitin-conjugating enzyme E2 2

1

0

High-throughput

0.426

High

453987

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.426

High

545990

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

575994

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

676970

SRO9
RNA-binding protein SRO9

1

0

High-throughput

0.426

High

737426

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

0

High-throughput

0.426

High

743274

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.426

High

780850

MUD2
Splicing factor MUD2

1

0

High-throughput

0.426

High

793867

SWD3
COMPASS component SWD3

1

0

High-throughput

0.426

High

796848

SIF2
SIR4-interacting protein SIF2

1

0

High-throughput

0.426

High

805570

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

High-throughput

0.426

High

807690

HRB1
Serine/arginine

1

0

High-throughput

0.426

High

825207

HOS4
Protein HOS4

1

0

High-throughput

0.426

High

845935

BRE2
COMPASS component BRE2

1

0

High-throughput

0.426

High

849752

MOB2
CBK1 kinase activator protein MOB2

1

0

High-throughput

0.426

High

863180

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.426

High

908514

ROM2
RHO1 GDP-GTP exchange protein 2

1

0

High-throughput

0.426

High

920682

TBG
Tubulin gamma chain

1

0

High-throughput

0.426

High

921160

H1
Histone H1

1

0

High-throughput

0.426

High

1038814

IMA1
Importin subunit alpha

1

0

High-throughput

0.426

High

1038816

SPP1
COMPASS component SPP1

1

0

High-throughput

0.426

High

1038817

SDC1
COMPASS component SDC1

1

0

High-throughput

0.426

High

1035369

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.407

High

806345

KOG1
Target of rapamycin complex 1 subunit KOG1

3

0

High-throughput

0.330

High

813840

MBO1
Gamma tubulin complex adapter SPC72

2

0

High-throughput

0.300

High

445367

CDC31
Cell division control protein 31

2

0

High-throughput

0.298

High

560756

KIN2
Serine/threonine-protein kinase KIN2

2

0

High-throughput

0.298

High

686903

BUB2
Mitotic check point protein BUB2

2

0

High-throughput

0.298

High

734621

NUD1
Protein NUD1

2

0

High-throughput

0.298

High

792438

BOI1
BEM1-interacting protein 1

2

0

High-throughput

0.298

High

793197

AKL1
Serine/threonine-protein kinase AKL1

2

0

High-throughput

0.298

High

794721

SEA4
SEH-associated protein 4

2

0

High-throughput

0.298

High

815842

BEM2
GTPase-activating protein BEM2/IPL2

2

0

High-throughput

0.298

High

817219

FIR1
Factor interacting with REF2

2

0

High-throughput

0.298

High

825017

TAO3
Cell morphogenesis protein PAG1

2

0

High-throughput

0.298

High

893414

PSP2
Protein PSP2

2

0

High-throughput

0.298

High

924099

CNM67
Chaotic nuclear migration protein 67

2

0

High-throughput

0.298

High

1038825

TCO89
Target of rapamycin complex 1 subunit TCO89

2

0

High-throughput

0.298

High

1038831

YB296
Uncharacterized protein YBR296C-A

1

0

High-throughput

0.282

High

672448

STE50
Protein STE50

1

0

High-throughput

0.251

Low

735661

SMY1
Kinesin-related protein SMY1

1

0

High-throughput

0.251

Low

737027

CDC3
Cell division control protein 3

1

0

High-throughput

0.251

Low

817753

TSC11
Target of rapamycin complex 2 subunit TSC11

1

0

High-throughput

0.251

Low

918761

NNF2
Protein NNF2

1

0

High-throughput

0.251

Low

919246

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.251

Low

1025013

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.251

Low

1038828

NYV1
Vacuolar v-SNARE NYV1

1

0

High-throughput

0.251

Low

1038830

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.251

Low

149916

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383857

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

410298

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433808

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

436126

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

442073

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

455224

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503201

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

512607

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

513175

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514792

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

558843

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

674791

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

688814

RFA3
Replication factor A protein 3

1

0

High-throughput

0.249

Low

689621

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

734188

EF2
Elongation factor 2

1

0

High-throughput

0.249

Low

743593

PT127
Putative mitochondrial translation system component PET127

1

0

High-throughput

0.249

Low

744768

MG101
Mitochondrial genome maintenance protein MGM101

1

0

High-throughput

0.249

Low

746753

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

747542

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

802342

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

874485

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

917461

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.249

Low

924613

NAT10
RNA cytidine acetyltransferase

1

0

High-throughput

0.249

Low

1033520

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1038818

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.249

Low

1038820

PAL1
Protein PAL1

1

0

High-throughput

0.249

Low

1038822

YL352
F-box protein YLR352W

1

0

High-throughput

0.249

Low

1038826

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

1038827

UBX3
UBX domain-containing protein 3

1

0

Small-scale

0.249

Low

1038829

CRM2
Homeostatic regulator of DAG

1

0

High-throughput

0.249

Low

361491

SODM
Superoxide dismutase [Mn], mitochondrial

1

0

High-throughput

0.232

Low

549979

KAR1
Cell division control protein KAR1

1

0

High-throughput

0.232

Low

577337

NSP1
Nucleoporin NSP1

1

0

High-throughput

0.232

Low

623933

MYO2
Myosin-2

1

0

High-throughput

0.232

Low

670200

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.232

Low

677153

LRE1
Laminarase-resistance protein LRE1

1

0

High-throughput

0.232

Low

790373

STT4
Phosphatidylinositol 4-kinase STT4

1

0

High-throughput

0.232

Low

790459

PAM1
Protein PAM1

1

0

High-throughput

0.232

Low

797363

ICS2
Increased copper sensitivity protein 2

1

0

High-throughput

0.232

Low

806052

KEL1
Kelch repeat-containing protein 1

1

0

High-throughput

0.232

Low

810748

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

815051

SNF7
Vacuolar-sorting protein SNF7

1

0

High-throughput

0.232

Low

834770

LST8
Target of rapamycin complex subunit LST8

1

0

High-throughput

0.232

Low

865481

BFA1
Mitotic check point protein BFA1

1

0

High-throughput

0.232

Low

871503

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025