Protein: DHE2
NAD-specific glutamate dehydrogenase (NAD-GDH) (EC 1.4.1.2)

Gene: DHE2, GDH2
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: P33327

Gene Ontology (top 5):
GO:0004352 - glutamate dehydrogenase (NAD+) activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006538 - L-glutamate catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751542

DHE2
NAD-specific glutamate dehydrogenase

1

0

High-throughput

0.560

High

660219

AATC
Aspartate aminotransferase, cytoplasmic

1

0

High-throughput

0.518

High

751553

DNM1
Dynamin-related protein DNM1

1

0

High-throughput

0.518

High

751554

YMN1
Uncharacterized membrane protein YML131W

1

1

High-throughput

0.515

High

456378

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

0

High-throughput

0.493

High

554494

RT13
Small ribosomal subunit protein mS27

1

0

High-throughput

0.493

High

751551

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

High-throughput

0.493

High

751559

SGT1
Protein SGT1

1

0

High-throughput

0.493

High

751562

NDOR1
NADPH-dependent diflavin oxidoreductase 1

1

0

High-throughput

0.486

High

392490

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

679532

CDC48
Cell division control protein 48

1

0

High-throughput

0.458

High

751545

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.458

High

751552

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

751561

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

394409

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

544321

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

579122

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

751546

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

360960

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.426

High

453515

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

526292

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

631881

SRP54
Signal recognition particle subunit SRP54

1

0

High-throughput

0.426

High

751544

NNK1
Nitrogen network kinase 1

2

0

High-throughput

0.333

High

751566

PEX11
Peroxisomal membrane protein PMP27

1

0

High-throughput

0.282

High

751556

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.279

Low

574788

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

0

High-throughput

0.269

Low

740785

MED18
Mediator of RNA polymerase II transcription subunit 18

1

0

High-throughput

0.269

Low

751555

SNU56
56 kDa U1 small nuclear ribonucleoprotein component

1

0

High-throughput

0.269

Low

751558

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.269

Low

751564

RPN6
26S proteasome regulatory subunit RPN6

1

0

High-throughput

0.269

Low

751550

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.265

Low

518249

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.249

Low

706650

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

734914

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.249

Low

751547

HOS4
Protein HOS4

1

0

High-throughput

0.249

Low

751548

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.249

Low

751557

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

751560

YL053
Putative uncharacterized protein YLR053C

1

0

Small-scale

0.249

Low

751565

RTN2
Reticulon-like protein 2

1

0

High-throughput

0.238

Low

358171

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

364999

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

592145

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

751279

BUD2
Inhibitory regulator protein BUD2/CLA2

1

0

High-throughput

0.232

Low

751543

MRP8
Uncharacterized protein MRP8

1

0

High-throughput

0.232

Low

751549

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

751563

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025