Protein: KPR2
Ribose-phosphate pyrophosphokinase 2 (EC 2.7.6.1) (Phosphoribosyl pyrophosphate synthase 2)

Gene: KPR2, PRS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: P38620

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0002189 - ribose phosphate diphosphokinase complex
GO:0004749 - ribose phosphate diphosphokinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

800685

KPR5
Ribose-phosphate pyrophosphokinase 5

5

17

Small-scale

0.920

High

746726

KPR1
Ribose-phosphate pyrophosphokinase 1

4

18

Small-scale

0.896

High

792597

KPR4
Ribose-phosphate pyrophosphokinase 4

1

18

High-throughput

0.698

High

800650

KPR2
Ribose-phosphate pyrophosphokinase 2

1

17

High-throughput

0.698

High

800651

KPR3
Ribose-phosphate pyrophosphokinase 3

1

17

High-throughput

0.618

High

800604

RIM11
Serine/threonine-protein kinase RIM11/MSD1

2

4

Small-scale

0.614

High

755233

NUF2
Kinetochore protein NUF2

2

5

Small-scale

0.543

High

800672

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

9

Small-scale

0.481

High

488952

SWI6
Regulatory protein SWI6

1

3

High-throughput

0.479

High

538337

PYC1
Pyruvate carboxylase 1

1

1

High-throughput

0.479

High

579310

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

665814

KPC1
Protein kinase C-like 1

1

14

High-throughput

0.479

High

734289

PYC2
Pyruvate carboxylase 2

1

1

High-throughput

0.479

High

744840

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

1

High-throughput

0.479

High

800653

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

4

High-throughput

0.479

High

800660

SAC3
Nuclear mRNA export protein SAC3

1

1

High-throughput

0.479

High

800662

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.479

High

800664

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

5

High-throughput

0.479

High

800666

MSN5
Protein MSN5

1

3

High-throughput

0.479

High

800674

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

5

High-throughput

0.479

High

800675

GDE1
Glycerophosphocholine phosphodiesterase GDE1

1

2

High-throughput

0.479

High

800681

NEW1
[NU+] prion formation protein 1

1

1

High-throughput

0.479

High

800684

GIN4
Serine/threonine-protein kinase GIN4

1

7

High-throughput

0.479

High

800687

DBP10
ATP-dependent RNA helicase DBP10

1

6

High-throughput

0.479

High

746330

RGT1
Glucose transport transcription regulator RGT1

1

0

High-throughput

0.458

High

763824

SKI2
Antiviral helicase SKI2

1

0

High-throughput

0.458

High

782666

ESL2
EST/SMG-like protein 2

1

0

High-throughput

0.458

High

800654

YEC5
Uncharacterized protein YEL025C

1

0

High-throughput

0.458

High

800656

SCC3
Cohesin subunit SCC3

1

0

High-throughput

0.458

High

800665

INP52
Polyphosphatidylinositol phosphatase INP52

1

0

High-throughput

0.458

High

800671

NST1
Stress response protein NST1

1

0

High-throughput

0.458

High

800676

MSH6
DNA mismatch repair protein MSH6

1

0

High-throughput

0.458

High

800680

ECM30
Protein ECM30

1

0

High-throughput

0.458

High

800682

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

800683

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.458

High

800686

HER1
HMG2-induced ER-remodeling protein 1

1

0

High-throughput

0.458

High

800691

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.458

High

523802

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.445

High

800652

SSZ1
Ribosome-associated complex subunit SSZ1

1

4

High-throughput

0.445

High

800655

SSB2
Ribosome-associated molecular chaperone SSB2

1

10

High-throughput

0.445

High

706973

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

800658

BNI1
Protein BNI1

1

1

High-throughput

0.437

High

800659

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

Small-scale

0.437

High

800673

CTF4
DNA polymerase alpha-binding protein

1

4

High-throughput

0.437

High

800677

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.437

High

800678

TDA9
Probable transcription factor TDA9

1

2

High-throughput

0.437

High

800689

TCB1
Tricalbin-1

1

5

High-throughput

0.437

High

575278

RAD9
DNA repair protein RAD9

1

0

High-throughput

0.249

Low

586069

DPOG
DNA polymerase gamma

1

0

High-throughput

0.249

Low

645162

PSB4
Proteasome subunit beta type-4

1

0

Small-scale

0.249

Low

674407

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.249

Low

757400

TFC3
Transcription factor tau 138 kDa subunit

1

0

High-throughput

0.249

Low

800657

AXL1
Putative protease AXL1

1

0

High-throughput

0.249

Low

800661

NET1
Nucleolar protein NET1

1

0

High-throughput

0.249

Low

800663

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.249

Low

800667

YGO0
Uncharacterized membrane protein YGL140C

1

0

High-throughput

0.249

Low

800668

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.249

Low

800669

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.249

Low

800670

TOF1
Topoisomerase 1-associated factor 1

1

0

High-throughput

0.249

Low

800679

CND1
Condensin complex subunit 1

1

0

High-throughput

0.249

Low

800688

RAX2
Bud site selection protein RAX2

1

0

High-throughput

0.249

Low

800690

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025