Protein: FEN1
Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (Flap structure-specific endonuclease 1) (RAD2 homolog nuclease 1) (RTH1 nuclease) (Structure-specific endonuclease RAD27)

Gene: FEN1, RAD27
Organism: Saccharomyces cerevisiae S288C
Interactions: 29
UniProt ID: P26793

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

586435

PCNA
Proliferating cell nuclear antigen

6

7

Small-scale

0.951

High

689756

DNA2
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2

2

7

Small-scale

0.621

High

416801

DNLI1
DNA ligase 1

1

0

Small-scale

0.614

High

689764

NHEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.537

High

544017

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.536

High

689759

JSN1
Protein JSN1

1

0

High-throughput

0.518

High

689752

IMB3
Importin subunit beta-3

1

1

High-throughput

0.515

High

689763

RRP5
rRNA biogenesis protein RRP5

1

2

High-throughput

0.515

High

381914

H4
Histone H4

1

1

Small-scale

0.501

High

647713

RFA1
Replication factor A protein 1

1

2

Small-scale

0.501

High

689762

MUS81
Crossover junction endonuclease MUS81

1

1

Small-scale

0.501

High

689754

NIP80
Protein NIP100

1

2

High-throughput

0.481

High

454515

PIF1
ATP-dependent DNA helicase PIF1

1

0

Small-scale

0.480

High

594894

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.479

High

649536

CHL1
ATP-dependent DNA helicase CHL1

1

3

Small-scale

0.479

High

679437

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

689751

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

689761

APJ1
J domain-containing protein APJ1

1

2

High-throughput

0.479

High

689765

ELG1
Telomere length regulation protein ELG1

1

1

Small-scale

0.479

High

689767

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

594230

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

689755

MMS4
Crossover junction endonuclease MMS4

1

0

Small-scale

0.458

High

689757

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

689758

ECO1
N-acetyltransferase ECO1

1

0

Small-scale

0.458

High

689760

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

0

Small-scale

0.458

High

689766

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

523228

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

526065

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

689753

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High


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Last updated: 11Aug2025