Protein: NIP80
Protein NIP100 (Protein NIP80)

Gene: NIP80, NIP100
Organism: Saccharomyces cerevisiae S288C
Interactions: 140
UniProt ID: P33420

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0000743 - nuclear migration involved in conjugation with cellular fusion
GO:0000922 - spindle pole
GO:0005737 - cytoplasm
GO:0005816 - spindle pole body

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

753054

NIP80
Protein NIP100

2

19

High-throughput

0.754

High

753160

MDY2
Ubiquitin-like protein MDY2

2

0

Small-scale

0.736

High

753070

ARP1
Centractin

5

20

Small-scale

0.714

High

753065

JNM1
Nuclear migration protein JNM1

6

0

Small-scale

0.703

High

753103

PAC11
WD repeat-containing protein PAC11

4

0

Small-scale

0.664

High

753140

ARP10
Actin-like protein ARP10

4

0

Small-scale

0.657

High

753151

LDB18
Protein LDB18

3

0

Small-scale

0.643

High

753079

END3
Actin cytoskeleton-regulatory complex protein END3

2

17

High-throughput

0.594

High

753069

SRO77
Lethal(2) giant larvae protein homolog SRO77

2

1

High-throughput

0.590

High

753128

HSK3
DASH complex subunit HSK3

2

1

High-throughput

0.584

High

753075

BZZ1
Protein BZZ1

2

12

High-throughput

0.576

High

753113

SNX4
Sorting nexin-4

2

5

Small-scale

0.559

High

753120

PFD6
Prefoldin subunit 6

2

0

High-throughput

0.552

High

753099

NDC80
Kinetochore protein NDC80

2

18

High-throughput

0.543

High

753059

SDS22
Protein phosphatase 1 regulatory subunit SDS22

1

9

High-throughput

0.536

High

753056

NUF2
Kinetochore protein NUF2

1

16

High-throughput

0.515

High

753158

SIZ2
E3 SUMO-protein ligase SIZ2

1

2

High-throughput

0.508

High

753145

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

438280

NOT3
General negative regulator of transcription subunit 3

1

1

High-throughput

0.481

High

597096

BIP
Endoplasmic reticulum chaperone BiP

1

11

High-throughput

0.481

High

689754

FEN1
Flap endonuclease 1

1

2

High-throughput

0.481

High

704863

KIP1
Kinesin-like protein KIP1

1

18

High-throughput

0.481

High

735606

SMY1
Kinesin-related protein SMY1

1

20

High-throughput

0.481

High

737299

CDC12
Cell division control protein 12

1

7

High-throughput

0.481

High

750609

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.481

High

753063

DID4
DOA4-independent degradation protein 4

1

3

High-throughput

0.481

High

753066

CDC27
Anaphase-promoting complex subunit CDC27

1

5

High-throughput

0.481

High

753071

SYSM
Serine--tRNA ligase, mitochondrial

1

1

High-throughput

0.481

High

753096

TBP6
Probable 26S proteasome subunit YTA6

1

12

High-throughput

0.481

High

753114

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.481

High

753125

YG3A
Uncharacterized protein YGR130C

1

19

High-throughput

0.481

High

753127

DID2
Vacuolar protein-sorting-associated protein 46

1

3

High-throughput

0.481

High

753133

VPS60
Vacuolar protein-sorting-associated protein 60

1

6

High-throughput

0.481

High

753138

VPS20
Vacuolar protein sorting-associated protein 20

1

6

High-throughput

0.481

High

753143

FAR10
Factor arrest protein 10

1

2

High-throughput

0.481

High

753154

SGO1
Shugoshin

1

1

High-throughput

0.481

High

753156

VIK1
Spindle pole body-associated protein VIK1

1

2

High-throughput

0.481

High

753159

GIN4
Serine/threonine-protein kinase GIN4

1

19

High-throughput

0.481

High

753162

GYP5
GTPase-activating protein GYP5

1

2

High-throughput

0.481

High

753164

NOT5
General negative regulator of transcription subunit 5

1

1

High-throughput

0.481

High

448519

RHO1
GTP-binding protein RHO1

1

20

High-throughput

0.464

High

448584

RHO2
GTP-binding protein RHO2

1

20

High-throughput

0.464

High

598476

SEN2
tRNA-splicing endonuclease subunit SEN2

1

0

High-throughput

0.460

High

600673

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.460

High

672392

STE50
Protein STE50

1

0

High-throughput

0.460

High

753061

SPC42
Spindle pole body component SPC42

1

0

High-throughput

0.460

High

753064

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.460

High

753078

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.460

High

753084

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.460

High

753087

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

753091

VFA1
VPS4-associated protein 1

1

0

High-throughput

0.460

High

753105

BUD6
Bud site selection protein 6

1

0

High-throughput

0.460

High

753131

SVL3
Styryl dye vacuolar localization protein 3

1

0

High-throughput

0.460

High

753136

BUL2
Ubiquitin ligase-binding protein BUL2

1

0

High-throughput

0.460

High

753147

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

753077

CSK2C
Casein kinase II subunit beta'

1

4

High-throughput

0.457

High

753080

MET30
F-box protein MET30

1

15

High-throughput

0.457

High

753146

SP382
Pre-mRNA-splicing factor SPP382

1

1

High-throughput

0.457

High

392497

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.445

High

481569

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.445

High

544335

SSB1
Ribosome-associated molecular chaperone SSB1

1

11

High-throughput

0.445

High

675866

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

753072

SSZ1
Ribosome-associated complex subunit SSZ1

1

9

High-throughput

0.445

High

753086

HSP7E
Heat shock protein SSC3, mitochondrial

1

11

High-throughput

0.445

High

753094

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

753115

TCPQ
T-complex protein 1 subunit theta

1

4

High-throughput

0.445

High

753126

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.445

High

753139

PFD5
Prefoldin subunit 5

1

2

High-throughput

0.445

High

484281

KEX1
Pheromone-processing carboxypeptidase KEX1

1

1

High-throughput

0.439

High

548683

RNA1
Ran GTPase-activating protein 1

1

9

High-throughput

0.439

High

700087

PRP45
Pre-mRNA-processing protein 45

1

3

High-throughput

0.439

High

736769

ASF2
Anti-silencing protein 2

1

18

High-throughput

0.439

High

736946

CDC3
Cell division control protein 3

1

7

High-throughput

0.439

High

749652

TYE7
Transcription factor TYE7

1

1

High-throughput

0.439

High

753057

CASP
Protein CASP

1

20

High-throughput

0.439

High

753058

LHS1
Heat shock protein 70 homolog LHS1

1

13

High-throughput

0.439

High

753067

AP2A
AP-2 complex subunit alpha

1

15

High-throughput

0.439

High

753068

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

13

High-throughput

0.439

High

753073

LAM4
Membrane-anchored lipid-binding protein LAM4

1

2

High-throughput

0.439

High

753074

ERP5
Protein ERP5

1

2

High-throughput

0.439

High

753076

SKN7
Transcription factor SKN7

1

1

High-throughput

0.439

High

753090

TSC11
Target of rapamycin complex 2 subunit TSC11

1

5

High-throughput

0.439

High

753098

BNR1
BNI1-related protein 1

1

10

High-throughput

0.439

High

753101

SA185
SIT4-associating protein SAP185

1

2

High-throughput

0.439

High

753102

MAD1
Spindle assembly checkpoint component MAD1

1

20

High-throughput

0.439

High

753104

NOP2
25S rRNA

1

3

High-throughput

0.439

High

753109

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.439

High

753116

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

1

High-throughput

0.439

High

753117

SGM1
Protein SGM1

1

18

High-throughput

0.439

High

753118

TEA1
TY1 enhancer activator

1

1

High-throughput

0.439

High

753119

KEL2
Kelch repeat-containing protein 2

1

8

High-throughput

0.439

High

753121

ITC1
Imitation switch two complex protein 1

1

2

High-throughput

0.439

High

753122

ERP6
Protein ERP6

1

2

High-throughput

0.439

High

753124

NNF2
Protein NNF2

1

1

High-throughput

0.439

High

753132

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

3

High-throughput

0.439

High

753137

SHE9
Sensitive to high expression protein 9, mitochondrial

1

1

High-throughput

0.439

High

753141

GLU2B
Glucosidase 2 subunit beta

1

2

High-throughput

0.439

High

753149

IMH1
Golgin IMH1

1

20

High-throughput

0.439

High

753152

YL031
Putative uncharacterized protein YLR031W

1

1

High-throughput

0.439

High

753083

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

753088

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

753111

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

753161

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

753150

ATG20
Autophagy-related protein 20

1

6

High-throughput

0.417

High

577082

SEC63
Protein translocation protein SEC63

1

4

High-throughput

0.407

High

670536

SIS1
Protein SIS1

1

4

High-throughput

0.407

High

753081

TCPG
T-complex protein 1 subunit gamma

1

4

High-throughput

0.407

High

753082

TCPD
T-complex protein 1 subunit delta

1

5

High-throughput

0.407

High

753100

DJP1
DnaJ-like protein 1

1

10

High-throughput

0.407

High

753163

NSI1
RNA polymerase I termination factor

1

0

High-throughput

0.269

Low

753110

GON7
EKC/KEOPS complex subunit GON7

1

0

High-throughput

0.265

Low

602119

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.251

Low

678262

ARE1
Sterol O-acyltransferase 1

1

0

High-throughput

0.251

Low

725957

SWC3
SWR1-complex protein 3

1

0

High-throughput

0.251

Low

743856

YEF3
Uncharacterized protein YEL043W

1

0

High-throughput

0.251

Low

753055

TIP20
Protein transport protein TIP20

1

0

High-throughput

0.251

Low

753062

T2EA
Transcription initiation factor IIE subunit alpha

1

0

High-throughput

0.251

Low

753085

HPH2
Protein HPH2

1

0

High-throughput

0.251

Low

753089

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

753092

PEA2
Protein PEA2

1

0

High-throughput

0.251

Low

753093

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.251

Low

753095

FDO1
Protein FDO1

1

0

High-throughput

0.251

Low

753097

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.251

Low

753106

GZF3
Protein GZF3

1

0

High-throughput

0.251

Low

753107

FMP32
Protein FMP32, mitochondrial

1

0

High-throughput

0.251

Low

753108

FAR3
Factor arrest protein 3

1

0

High-throughput

0.251

Low

753112

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

753129

ULP1
Ubiquitin-like-specific protease 1

1

0

High-throughput

0.251

Low

753130

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.251

Low

753134

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

753135

TAF8
Transcription initiation factor TFIID subunit 8

1

0

High-throughput

0.251

Low

753142

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

753144

MMR1
Mitochondrial MYO2 receptor-related protein 1

1

0

High-throughput

0.251

Low

753148

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.251

Low

753153

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.251

Low

753155

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

0

High-throughput

0.251

Low

753060

MUD2
Splicing factor MUD2

1

0

Small-scale

0.249

Low

753157

YD211
Uncharacterized protein YDL211C

1

0

High-throughput

0.249

Low

753123

SWC4
SWR1-complex protein 4

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025