Protein: NHEJ1
Non-homologous end-joining protein 1

Gene: NHEJ1, NEJ1
Organism: Saccharomyces cerevisiae S288C
Interactions: 51
UniProt ID: Q06148

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006303 - double-strand break repair via nonhomologous end joining
GO:0031965 - nuclear membrane
GO:0032807 - DNA ligase IV complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917752

XRCC4
Non-homologous end-joining factor LIF1

12

0

Small-scale

0.727

High

441259

KAPA
cAMP-dependent protein kinase type 1

2

1

Small-scale

0.629

High

1046622

KU80
ATP-dependent DNA helicase II subunit 2

2

1

Small-scale

0.595

High

1053919

ESA1
Histone acetyltransferase ESA1

2

0

Small-scale

0.577

High

745535

MRE11
Double-strand break repair protein MRE11

2

0

Small-scale

0.559

High

557772

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.549

High

677894

DPO4
DNA polymerase IV

1

0

Small-scale

0.537

High

689764

FEN1
Flap endonuclease 1

1

0

Small-scale

0.537

High

1053916

NHEJ1
Non-homologous end-joining protein 1

1

0

Small-scale

0.529

High

656625

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

448804

SNF1
Carbon catabolite-derepressing protein kinase

1

0

High-throughput

0.480

High

692435

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

917175

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.480

High

441395

KAPB
cAMP-dependent protein kinase type 2

1

1

Small-scale

0.479

High

525204

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.479

High

745453

KU70
ATP-dependent DNA helicase II subunit 1

1

1

Small-scale

0.479

High

1053920

ARP8
Actin-like protein ARP8

1

1

Small-scale

0.479

High

763296

SGS1
ATP-dependent helicase SGS1

1

0

Small-scale

0.460

High

863084

COM1
DNA endonuclease SAE2

1

0

Small-scale

0.460

High

1053917

SP382
Pre-mRNA-splicing factor SPP382

1

0

Small-scale

0.460

High

364749

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.458

High

419510

H2A1
Histone H2A.1

1

0

Small-scale

0.458

High

444799

SIR2
NAD-dependent histone deacetylase SIR2

1

0

Small-scale

0.458

High

454761

KAPR
cAMP-dependent protein kinase regulatory subunit

1

0

Small-scale

0.458

High

575290

RAD9
DNA repair protein RAD9

1

0

Small-scale

0.458

High

617872

DDR48
Stress protein DDR48

1

0

Small-scale

0.458

High

642474

MCK1
Protein kinase MCK1

1

0

Small-scale

0.458

High

709468

HRR25
Casein kinase I homolog HRR25

1

0

Small-scale

0.458

High

713039

MCM2
DNA replication licensing factor MCM2

1

0

Small-scale

0.458

High

776650

DEF1
RNA polymerase II degradation factor 1

1

0

Small-scale

0.458

High

801023

RFC1
Replication factor C subunit 1

1

0

Small-scale

0.458

High

807787

CSK2C
Casein kinase II subunit beta'

1

0

Small-scale

0.458

High

818096

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

0

Small-scale

0.458

High

850579

RSC8
Chromatin structure-remodeling complex protein RSC8

1

0

Small-scale

0.458

High

874345

HOSC
Homocitrate synthase, cytosolic isozyme

1

0

Small-scale

0.458

High

917323

INO80
Chromatin-remodeling ATPase INO80

1

0

Small-scale

0.458

High

948657

ACT
Actin

1

0

Small-scale

0.458

High

1048408

IRC21
Increased recombination centers protein 21

1

0

Small-scale

0.458

High

1053918

DNLI4
DNA ligase 4

1

0

Small-scale

0.458

High

1053921

EAF3
Chromatin modification-related protein EAF3

1

0

Small-scale

0.458

High

527722

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

742437

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

546344

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

671142

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

844378

ETFB
Probable electron transfer flavoprotein subunit beta

1

0

High-throughput

0.269

Low

678052

HSP30
30 kDa heat shock protein

1

0

Small-scale

0.249

Low

688825

RFA3
Replication factor A protein 3

1

0

Small-scale

0.249

Low

779195

NDK
Nucleoside diphosphate kinase

1

0

Small-scale

0.249

Low

830068

CDC1
Cell division control protein 1

1

0

Small-scale

0.249

Low

797996

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025