Protein: DCM
DNA-cytosine methyltransferase (EC 2.1.1.37) (Type II methyltransferase M.EcoKDcm) (M.EcoKDcm)

Gene: DCM
Organism: Escherichia coli K-12
Interactions: 22
UniProt ID: P0AED9

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0003886 - DNA (cytosine-5-)-methyltransferase activity
GO:0009307 - DNA restriction-modification system
GO:0032259 - methylation
GO:0044027 - negative regulation of gene expression via chromosomal CpG island methylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

492727

RL1
Large ribosomal subunit protein uL1

2

1

High-throughput

0.549

High

493906

RS3
Small ribosomal subunit protein uS3

2

2

High-throughput

0.549

High

500164

MNME
tRNA modification GTPase MnmE

2

1

High-throughput

0.549

High

500163

MUKB
Chromosome partition protein MukB

1

0

High-throughput

0.513

High

500165

RL2
Large ribosomal subunit protein uL2

1

1

High-throughput

0.489

High

500162

PARE
DNA topoisomerase 4 subunit B

1

0

High-throughput

0.458

High

493625

RS20
Small ribosomal subunit protein bS20

2

0

High-throughput

0.313

High

497492

RL13
Large ribosomal subunit protein uL13

2

0

High-throughput

0.313

High

500159

RL21
Large ribosomal subunit protein bL21

2

0

High-throughput

0.313

High

500160

RS14
Small ribosomal subunit protein uS14

2

0

High-throughput

0.313

High

500168

PGAD
Biofilm PGA synthesis protein PgaD

1

0

High-throughput

0.282

High

449844

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex

1

0

High-throughput

0.279

Low

489604

CH60
Chaperonin GroEL

1

0

High-throughput

0.279

Low

499372

PURR
HTH-type transcriptional repressor PurR

1

0

High-throughput

0.279

Low

500019

AMN
AMP nucleosidase

1

0

High-throughput

0.279

Low

500161

RIMK
Ribosomal protein bS6--L-glutamate ligase

1

0

High-throughput

0.279

Low

500169

HPRS
Sensor histidine kinase HprS

1

0

High-throughput

0.279

Low

500170

CITG
2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase

1

0

High-throughput

0.279

Low

382690

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.253

Low

494274

RS5
Small ribosomal subunit protein uS5

1

0

High-throughput

0.253

Low

500166

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.253

Low

500167

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.253

Low


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Last updated: 11Aug2025