HitPredict

Interactor 1: LTE1 (P07866)
Guanine nucleotide exchange factor LTE1 (Low temperature essential protein 1)
Gene: LTE1

Interactor 2: RSR1 (P13856)
Ras-related protein RSR1 (EC 3.6.5.2)
Gene: RSR1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21149565
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RasGEF, Ras~RasGEF_N
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1435 Sc			1 272
+	Sc
		376173 LTE1_YEAST (1-1435): 0: 2228: 100.00		RAS1_YEAST (1-208): 4.52e-45: 155: 49.04
+	Hs
		959416 RGL1_HUMAN (1027-1434): 5.24e-103: 348: 16.56		RAP1B_HUMAN (1-180): 4.01e-80: 241: 56.11
+	Hs
		982138 RGL1_HUMAN (1027-1434): 5.24e-103: 348: 16.56		RAP1A_HUMAN (1-170): 3.44e-80: 241: 58.82
+	Hs
		982107 RPGF6_HUMAN (1013-1418): 2.2e-87: 316: 16.89		RAP1A_HUMAN (1-170): 3.44e-80: 241: 58.82
+	Hs
		982144 RPGF2_HUMAN (1012-1427): 1.14e-86: 314: 16.59		RAP1A_HUMAN (1-170): 3.44e-80: 241: 58.82
+	Dm
		473574 Q9VMF3_DROME (1089-1432): 2.59e-78: 288: 14.84		RAP1_DROME (1-165): 1.2e-85: 255: 59.39
+	Hs
		982077 RPGF1_HUMAN (1067-1431): 2.55e-81: 293: 16.58		RAP1A_HUMAN (1-170): 3.44e-80: 241: 58.82
+	Hs
		982110 RPGF4_HUMAN (1142-1434): 2.08e-78: 283: 18.42		RAP1A_HUMAN (1-170): 3.44e-80: 241: 58.82
+	Hs
		1370968 RGL1_HUMAN (1027-1434): 5.24e-103: 348: 16.56		RIT1_HUMAN (2-191): 4.93e-53: 173: 45.31
+	Hs
		182042 RGL2_HUMAN (1016-1434): 6.7e-78: 277: 14.51		RAP1B_HUMAN (1-180): 4.01e-80: 241: 56.11
+	Hs
		518630 RGL1_HUMAN (1027-1434): 5.24e-103: 348: 16.56		RAP2A_HUMAN (1-165): 9.3e-48: 158: 55.15
+	Hs
		967243 RGL1_HUMAN (1027-1434): 5.24e-103: 348: 16.56		RRAS2_HUMAN (4-204): 2.41e-46: 155: 46.77
+	Hs
		959452 RPGF2_HUMAN (1012-1427): 1.14e-86: 314: 16.59		RAP2B_HUMAN (1-165): 2.39e-51: 167: 55.76
+	Hs
		518616 RPGF6_HUMAN (1013-1418): 2.2e-87: 316: 16.89		RAP2A_HUMAN (1-165): 9.3e-48: 158: 55.15
+	Hs
		1060692 SOS1_HUMAN (1069-1429): 2.32e-83: 302: 14.25		RIT2_HUMAN (2-169): 4.85e-50: 165: 48.81
+	Hs
		959440 RPGF1_HUMAN (1067-1431): 2.55e-81: 293: 16.58		RAP2B_HUMAN (1-165): 2.39e-51: 167: 55.76
+	Hs
		518618 RPGF4_HUMAN (1142-1434): 2.08e-78: 283: 18.42		RAP2A_HUMAN (1-165): 9.3e-48: 158: 55.15
+	Dm
		355987 Q9VMF3_DROME (1089-1432): 2.59e-78: 288: 14.84		O96692_DROME (1-165): 1.65e-43: 147: 50.30
+	Hs
		182044 RGL2_HUMAN (1016-1434): 6.7e-78: 277: 14.51		RRAS2_HUMAN (4-204): 2.41e-46: 155: 46.77
+	Hs
		182036 RGL2_HUMAN (1016-1434): 6.7e-78: 277: 14.51		RALA_HUMAN (4-171): 1.62e-44: 151: 45.24