Protein: BEM1
Bud emergence protein 1 (Suppressor of RHO3 protein 1)

Gene: BEM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 103
UniProt ID: P29366

Gene Ontology (top 5):
GO:0000131 - incipient cellular bud site
GO:0000282 - cellular bud site selection
GO:0000747 - conjugation with cellular fusion
GO:0000753 - cell morphogenesis involved in conjugation with cellular fusion
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

542948

CDC24
Cell division control protein 24

31

20

Small-scale

0.994

High

711501

BOI2
BEM1-interacting protein 2

10

20

Small-scale

0.975

High

711493

BOI1
BEM1-interacting protein 1

10

18

Small-scale

0.974

High

711505

CLA4
Serine/threonine-protein kinase CLA4

7

20

Small-scale

0.965

High

711474

BEM1
Bud emergence protein 1

2

18

Small-scale

0.791

High

711524

STE20
Serine/threonine-protein kinase STE20

15

20

Small-scale

0.763

High

711530

RGA2
Rho-type GTPase-activating protein 2

2

16

Small-scale

0.757

High

618330

CDC42
Cell division control protein 42

8

20

Small-scale

0.753

High

636916

FAR1
Cyclin-dependent kinase inhibitor FAR1

6

0

Small-scale

0.703

High

624839

EXO70
Exocyst complex component EXO70

4

1

Small-scale

0.677

High

646716

SEC15
Exocyst complex component SEC15

4

0

Small-scale

0.671

High

568727

RSR1
Ras-related protein RSR1

2

5

Small-scale

0.636

High

711485

STE5
Protein STE5

3

0

Small-scale

0.633

High

711517

SEC5
Exocyst complex component SEC5

2

0

Small-scale

0.610

High

711479

CDC11
Cell division control protein 11

2

9

Small-scale

0.594

High

711534

NBA1
Protein NBA1

2

0

Small-scale

0.593

High

711486

SWE1
Mitosis inhibitor protein kinase SWE1

2

20

High-throughput

0.590

High

711515

MPS1
Serine/threonine-protein kinase MPS1

2

8

High-throughput

0.586

High

637821

MSB1
Morphogenesis-related protein MSB1

2

0

Small-scale

0.561

High

364388

CDK1
Cyclin-dependent kinase 1

1

3

High-throughput

0.561

High

711519

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

5

High-throughput

0.552

High

711482

SEC8
Exocyst complex component SEC8

2

0

Small-scale

0.547

High

711508

KEL2
Kelch repeat-containing protein 2

1

7

High-throughput

0.541

High

711512

FPK1
Flippase kinase 1

1

12

High-throughput

0.541

High

711523

MET31
Transcriptional regulator MET31

1

1

High-throughput

0.541

High

711476

XPO1
Exportin-1

1

3

High-throughput

0.536

High

711541

SKM1
Serine/threonine-protein kinase SKM1

1

20

Small-scale

0.527

High

711529

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.527

High

677653

LDB16
Protein LDB16

1

0

High-throughput

0.518

High

711483

NFU1
NifU-like protein, mitochondrial

1

0

High-throughput

0.518

High

711487

PDR3
Transcription factor PDR3

1

0

High-throughput

0.518

High

711499

DSS1
Exoribonuclease II, mitochondrial

1

0

High-throughput

0.518

High

711518

2ABA
Protein phosphatase PP2A regulatory subunit B

1

0

High-throughput

0.518

High

711525

EFR3
Protein EFR3

1

0

High-throughput

0.518

High

711531

YD306
F-box protein YDR306C

1

0

High-throughput

0.518

High

711535

AVO1
Target of rapamycin complex 2 subunit AVO1

1

0

High-throughput

0.518

High

711540

YPR1
Aldehyde reductase YPR1

1

0

High-throughput

0.518

High

711542

AFI1
ARF3-interacting protein 1

1

0

High-throughput

0.518

High

711539

LAS17
Proline-rich protein LAS17

1

20

Small-scale

0.515

High

517936

SSBP1
Single-stranded nucleic acid-binding protein

1

3

High-throughput

0.501

High

684608

CDC20
APC/C activator protein CDC20

1

7

Small-scale

0.501

High

711496

KSP1
Serine/threonine-protein kinase KSP1

1

12

High-throughput

0.501

High

577536

CYC8
General transcriptional corepressor CYC8

1

5

High-throughput

0.494

High

711490

MTH1
Protein MTH1

1

1

High-throughput

0.494

High

711504

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

5

High-throughput

0.494

High

711522

STD1
Protein STD1

1

1

High-throughput

0.494

High

711498

AXL2
Axial budding pattern protein 2

1

0

Small-scale

0.493

High

711520

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

2

20

Small-scale

0.492

High

376180

RAS1
Ras-like protein 1

1

14

Small-scale

0.481

High

376214

RAS2
Ras-like protein 2

1

9

Small-scale

0.481

High

623790

MYO2
Myosin-2

1

5

Small-scale

0.481

High

654703

SPA2
Protein SPA2

1

17

Small-scale

0.481

High

448855

STE7
Serine/threonine-protein kinase STE7

1

20

Small-scale

0.479

High

578987

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

599333

FUS3
Mitogen-activated protein kinase FUS3

1

2

Small-scale

0.479

High

624721

PMA2
Plasma membrane ATPase 2

1

4

High-throughput

0.479

High

660312

STE11
Serine/threonine-protein kinase STE11

1

8

Small-scale

0.479

High

711477

SNC1
Synaptobrevin homolog 1

1

1

Small-scale

0.479

High

711478

MSB2
Signaling mucin MSB2

1

6

Small-scale

0.479

High

711488

SNC2
Synaptobrevin homolog 2

1

1

Small-scale

0.479

High

711500

SSO2
Protein SSO2

1

5

Small-scale

0.479

High

711514

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

711538

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

711516

ACT
Actin

1

20

Small-scale

0.462

High

711495

FKS1
1,3-beta-glucan synthase component FKS1

1

0

Small-scale

0.460

High

711503

BUD6
Bud site selection protein 6

1

0

Small-scale

0.460

High

434897

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

711506

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

711521

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

711532

HBT1
Protein HBT1

1

0

High-throughput

0.458

High

711536

SGO1
Shugoshin

1

0

High-throughput

0.458

High

711497

YHS2
MIP18 family protein YHR122W

1

1

High-throughput

0.457

High

403395

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

3

High-throughput

0.445

High

427169

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.445

High

526108

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

544072

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

592070

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.445

High

711489

SEC3
Exocyst complex component SEC3

1

20

Small-scale

0.445

High

711494

EXO84
Exocyst complex component EXO84

1

1

Small-scale

0.445

High

711502

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

711507

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.445

High

711509

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

2

High-throughput

0.445

High

711484

SSO1
Protein SSO1

1

5

Small-scale

0.437

High

711537

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

684650

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

711481

SEC6
Exocyst complex component SEC6

1

0

Small-scale

0.426

High

464565

PBS2
MAP kinase kinase PBS2

1

20

Small-scale

0.408

High

531642

RL4A
Large ribosomal subunit protein uL4A

1

2

High-throughput

0.407

High

711480

YEF3
Uncharacterized protein YEL043W

2

0

High-throughput

0.317

High

711511

CF130
Protein CAF130

2

0

High-throughput

0.317

High

673149

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.282

High

711491

SFK1
Protein SFK1

1

0

High-throughput

0.282

High

711492

VBA5
Vacuolar basic amino acid transporter 5

1

0

High-throughput

0.282

High

711513

YN9A
Uncharacterized isomerase YNR071C

1

0

High-throughput

0.282

High

711527

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.282

High

711528

TERT
Telomerase reverse transcriptase

1

0

High-throughput

0.282

High

711533

LDB18
Protein LDB18

1

0

High-throughput

0.282

High

94543

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.251

Low

706406

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

711510

MUP1
High-affinity methionine permease

1

0

High-throughput

0.249

Low

711526

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

711475

RL8B
Large ribosomal subunit protein eL8B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025