Protein: CBF3A
Centromere DNA-binding protein complex CBF3 subunit A (Centromere-binding factor 2) (Chromosome transmission fidelity protein 14) (Kinetochore protein CTF14)

Gene: CBF3A, CBF2
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P32504

Gene Ontology (top 5):
GO:0000022 - mitotic spindle elongation
GO:0000776 - kinetochore
GO:0000779 - condensed chromosome, centromeric region
GO:0000921 - septin ring assembly
GO:0003677 - DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

738727

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

4

1

Small-scale

0.878

High

738757

BIR1
Chromosomal passenger complex protein BIR1

8

1

Small-scale

0.748

High

738752

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

5

1

Small-scale

0.709

High

738737

CBF3C
Centromere DNA-binding protein complex CBF3 subunit C

6

0

Small-scale

0.705

High

738751

DSN1
Kinetochore-associated protein DSN1

6

0

Small-scale

0.686

High

738748

AURK
Aurora kinase

4

0

Small-scale

0.662

High

738760

SKP1
Suppressor of kinetochore protein 1

4

0

Small-scale

0.648

High

738788

SCM3
Protein SCM3

3

1

Small-scale

0.646

High

601999

CBF1
Centromere-binding protein 1

2

1

Small-scale

0.629

High

738732

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

3

0

Small-scale

0.612

High

642354

MCK1
Protein kinase MCK1

2

0

Small-scale

0.579

High

738777

RUVB1
RuvB-like protein 1

2

1

High-throughput

0.571

High

738744

INCE
Inner centromere protein SLI15

2

0

Small-scale

0.561

High

738745

CENPU
Inner kinetochore subunit AME1

2

0

Small-scale

0.559

High

738749

SAP1
Protein SAP1

2

0

Small-scale

0.559

High

738759

UBC9
SUMO-conjugating enzyme UBC9

2

0

Small-scale

0.559

High

738766

NIS1
Protein NIS1

2

0

Small-scale

0.559

High

736157

PLC1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1

1

0

Small-scale

0.549

High

738773

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.549

High

738763

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.513

High

585883

CSK21
Casein kinase II subunit alpha

1

1

Small-scale

0.501

High

622899

CSK22
Casein kinase II subunit alpha'

1

1

Small-scale

0.501

High

738764

CENPQ
Inner kinetochore subunit OKP1

1

0

Small-scale

0.493

High

738780

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.493

High

677841

RDS1
Regulator of drug sensitivity 1

1

0

High-throughput

0.486

High

574783

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

0

Small-scale

0.480

High

738739

CENPA
Histone H3-like centromeric protein CSE4

1

1

High-throughput

0.479

High

649539

CHL1
ATP-dependent DNA helicase CHL1

1

0

Small-scale

0.460

High

738785

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

Small-scale

0.460

High

738787

SMT3
Ubiquitin-like protein SMT3

1

0

Small-scale

0.460

High

531454

RT01
Small ribosomal subunit protein mS43

1

0

High-throughput

0.458

High

556998

AAKG
5'-AMP-activated protein kinase subunit gamma

1

0

High-throughput

0.458

High

702299

MGLL
Monoglyceride lipase

1

0

High-throughput

0.458

High

738728

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

738734

YKJ1
CRAL-TRIO domain-containing protein YKL091C

1

0

High-throughput

0.458

High

738738

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

738746

KPR3
Ribose-phosphate pyrophosphokinase 3

1

0

High-throughput

0.458

High

738756

SMC3
Structural maintenance of chromosomes protein 3

1

0

Small-scale

0.458

High

738758

BCA2
Branched-chain-amino-acid aminotransferase, cytosolic

1

0

High-throughput

0.458

High

738767

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

738774

DIG2
Down-regulator of invasive growth 2

1

0

High-throughput

0.458

High

738781

SGO1
Shugoshin

1

0

High-throughput

0.458

High

738783

CMR3
Zinc finger protein CRM3

1

0

High-throughput

0.458

High

738784

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

523377

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526191

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

678302

RSC6
Chromatin structure-remodeling complex protein RSC6

1

1

High-throughput

0.445

High

738729

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

738730

SWI3
SWI/SNF complex subunit SWI3

1

1

High-throughput

0.445

High

738731

STH1
Nuclear protein STH1/NPS1

1

1

High-throughput

0.445

High

738753

RSC8
Chromatin structure-remodeling complex protein RSC8

1

1

High-throughput

0.445

High

738765

SNF12
Transcription regulatory protein SNF12

1

1

High-throughput

0.445

High

738769

H3
Histone H3

1

1

High-throughput

0.445

High

738778

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

738789

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.445

High

149201

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.426

High

381451

H2B2
Histone H2B.2

1

0

High-throughput

0.426

High

381956

H4
Histone H4

1

0

High-throughput

0.426

High

419656

H2A2
Histone H2A.2

1

0

High-throughput

0.426

High

544188

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

561439

TBP
TATA-box-binding protein

1

0

High-throughput

0.426

High

682905

MSH2
DNA mismatch repair protein MSH2

1

0

High-throughput

0.426

High

737660

HIR2
Protein HIR2

1

0

High-throughput

0.426

High

738733

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.426

High

738736

TAF14
Transcription initiation factor TFIID subunit 14

1

0

High-throughput

0.426

High

738742

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

0

High-throughput

0.426

High

738743

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

1

0

High-throughput

0.426

High

738747

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

738754

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.426

High

738761

MCM6
DNA replication licensing factor MCM6

1

0

High-throughput

0.426

High

738768

ACT
Actin

1

0

High-throughput

0.426

High

738770

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

738772

TBF1
Protein TBF1

1

0

High-throughput

0.426

High

738775

NHP10
Non-histone protein 10

1

0

High-throughput

0.426

High

738776

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

0

High-throughput

0.426

High

738782

NSL1
Kinetochore-associated protein NSL1

1

0

High-throughput

0.426

High

738755

NET1
Nucleolar protein NET1

1

1

High-throughput

0.407

High

738771

TOF2
Topoisomerase 1-associated factor 2

1

1

High-throughput

0.407

High

738750

FIR1
Factor interacting with REF2

2

0

Small-scale

0.304

High

360957

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

738735

ZRT3
Zinc-regulated transporter 3

1

0

High-throughput

0.249

Low

738740

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

738741

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

738762

YIP5
Protein YIP5

1

0

High-throughput

0.249

Low

738779

YL283
Uncharacterized protein YLR283W, mitochondrial

1

0

High-throughput

0.249

Low

738786

RDL1
Thiosulfate:glutathione sulfurtransferase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025