Protein: NSE3
Non-structural maintenance of chromosome element 3 (Non-SMC element 3)

Gene: NSE3
Organism: Saccharomyces cerevisiae S288C
Interactions: 63
UniProt ID: Q05541

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1051547

SMC5
Structural maintenance of chromosomes protein 5

7

1

Small-scale

0.963

High

845907

NSE4
Non-structural maintenance of chromosome element 4

7

0

Small-scale

0.919

High

1051546

NSE1
Non-structural maintenance of chromosomes element 1

6

0

Small-scale

0.903

High

1051558

SMC6
Structural maintenance of chromosomes protein 6

6

1

Small-scale

0.729

High

801139

NSE2
E3 SUMO-protein ligase MMS21

4

0

Small-scale

0.661

High

845899

UAP1
UDP-N-acetylglucosamine pyrophosphorylase

2

0

High-throughput

0.582

High

742394

HSP7F
Heat shock protein homolog SSE1

2

2

High-throughput

0.552

High

924732

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.518

High

1037085

HAP5
Transcriptional activator HAP5

1

0

High-throughput

0.518

High

1051543

RIF2
Protein RIF2

1

0

High-throughput

0.518

High

1051550

TFB6
General transcription and DNA repair factor IIH subunit TFB6

1

0

High-throughput

0.493

High

798512

REI1
Cytoplasmic 60S subunit biogenesis factor REI1

1

0

Small-scale

0.460

High

805988

RT107
Regulator of Ty1 transposition protein 107

1

0

Small-scale

0.460

High

815957

UBP9
Ubiquitin carboxyl-terminal hydrolase 9

1

0

Small-scale

0.460

High

550694

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.458

High

708188

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

817311

KRE29
DNA repair protein KRE29

1

0

High-throughput

0.458

High

504573

YD14B
Transposon Ty1-DR5 Gag-Pol polyprotein

1

6

High-throughput

0.445

High

504584

YD15B
Transposon Ty1-DR6 Gag-Pol polyprotein

1

6

High-throughput

0.445

High

525155

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527679

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

546277

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

819798

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

1043450

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

6

High-throughput

0.445

High

1043458

YE12B
Transposon Ty1-ER2 Gag-Pol polyprotein

1

6

High-throughput

0.445

High

1044197

YD11B
Transposon Ty1-DR1 Gag-Pol polyprotein

1

6

High-throughput

0.445

High

1051554

YB12B
Transposon Ty1-BR Gag-Pol polyprotein

1

6

High-throughput

0.445

High

1051560

YD12B
Transposon Ty1-DR3 Gag-Pol polyprotein

1

6

High-throughput

0.445

High

803778

PIH1
Protein interacting with Hsp90 1

1

0

High-throughput

0.438

High

808307

RRP8
25S rRNA

1

0

High-throughput

0.438

High

1051542

SPO77
Sporulation-specific protein 77

1

0

High-throughput

0.438

High

1051553

APC9
Anaphase-promoting complex subunit 9

1

0

High-throughput

0.438

High

599075

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.426

High

671127

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

739202

PRP19
Pre-mRNA-processing factor 19

1

0

High-throughput

0.426

High

752731

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

802985

YHF0
Uncharacterized protein YHL050C

1

0

High-throughput

0.426

High

804456

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

813571

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.426

High

825353

SHQ1
Protein SHQ1

1

0

High-throughput

0.426

High

849896

IES1
Ino eighty subunit 1

1

0

High-throughput

0.426

High

871508

ASK10
Activator of SKN7 protein 10

1

0

High-throughput

0.426

High

925306

BOP3
Protein BOP3

1

0

High-throughput

0.426

High

1030543

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

1

0

High-throughput

0.426

High

1035256

NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit

1

0

High-throughput

0.426

High

1051545

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

0

High-throughput

0.426

High

1051548

CUE5
Ubiquitin-binding protein CUE5

1

0

High-throughput

0.426

High

1051559

RTP1
RNA polymerase II assembly factor RTP1

1

0

High-throughput

0.426

High

1051549

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.269

Low

677732

GEX1
Glutathione exchanger 1

1

0

Small-scale

0.251

Low

812966

YAN4
Uncharacterized protein YAR064W

1

0

High-throughput

0.238

Low

1051556

ERP4
Protein ERP4

1

0

High-throughput

0.238

Low

368754

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.232

Low

554968

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.232

Low

609242

CLC1
Clathrin light chain

1

0

High-throughput

0.232

Low

813326

RRF2M
Ribosome-releasing factor 2, mitochondrial

1

0

High-throughput

0.232

Low

1035293

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.232

Low

1048240

SOV1
Protein SOV1, mitochondrial

1

0

High-throughput

0.232

Low

1051544

RRP9
Ribosomal RNA-processing protein 9

1

0

High-throughput

0.232

Low

1051551

RSA1
Ribosome assembly 1 protein

1

0

High-throughput

0.232

Low

1051552

MMT2
Mitochondrial metal transporter 2

1

0

High-throughput

0.232

Low

1051555

SUL2
Sulfate permease 2

1

0

High-throughput

0.232

Low

1051557

ATC8
Probable phospholipid-transporting ATPase DNF3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025