Protein: NSE2
E3 SUMO-protein ligase MMS21 (EC 2.3.2.-) (E3 SUMO-protein transferase MMS21) (Methyl methanesulfonate-sensitivity protein 21) (Non-structural maintenance of chromosome element 2) (Non-SMC element 2)

Gene: NSE2, MMS21
Organism: Saccharomyces cerevisiae S288C
Interactions: 27
UniProt ID: P38632

Gene Ontology (top 5):
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0005635 - nuclear envelope
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

801142

SMC5
Structural maintenance of chromosomes protein 5

12

1

Small-scale

0.983

High

801135

UBC9
SUMO-conjugating enzyme UBC9

8

0

Small-scale

0.916

High

801145

SMT3
Ubiquitin-like protein SMT3

2

0

Small-scale

0.738

High

801146

SMC6
Structural maintenance of chromosomes protein 6

6

1

Small-scale

0.724

High

801134

NSE4
Non-structural maintenance of chromosome element 4

5

0

Small-scale

0.681

High

801139

NSE3
Non-structural maintenance of chromosome element 3

4

0

Small-scale

0.661

High

801137

NSE5
Non-structural maintenance of chromosome element 5

3

0

Small-scale

0.630

High

801132

RT107
Regulator of Ty1 transposition protein 107

3

0

Small-scale

0.614

High

560235

TOP3
DNA topoisomerase 3

2

0

Small-scale

0.577

High

763276

SGS1
ATP-dependent helicase SGS1

2

0

Small-scale

0.577

High

801133

KRE29
DNA repair protein KRE29

2

0

Small-scale

0.559

High

801136

IMB5
Importin subunit beta-5

1

0

Small-scale

0.549

High

642037

DPOE
DNA polymerase epsilon catalytic subunit A

1

0

Small-scale

0.537

High

745442

KU70
ATP-dependent DNA helicase II subunit 1

1

0

Small-scale

0.480

High

801143

MCA1
Metacaspase-1

1

0

Small-scale

0.480

High

664433

MCM3
DNA replication licensing factor MCM3

1

0

Small-scale

0.458

High

665177

DPB2
DNA polymerase epsilon subunit B

1

0

Small-scale

0.458

High

801138

POB3
FACT complex subunit POB3

1

0

Small-scale

0.458

High

801140

NSE1
Non-structural maintenance of chromosomes element 1

1

0

Small-scale

0.458

High

801141

CDC45
Cell division control protein 45

1

0

Small-scale

0.458

High

801144

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

523810

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526581

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

741490

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

510455

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.426

High

544717

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

676834

DCC1
Sister chromatid cohesion protein DCC1

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025