Protein: TLR3
Toll-like receptor 3 (CD antigen CD283)

Gene: TLR3
Organism: Mus musculus
Interactions: 24
UniProt ID: Q99MB1

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001774 - microglial cell activation
GO:0002224 - toll-like receptor signaling pathway
GO:0002730 - regulation of dendritic cell cytokine production
GO:0003725 - double-stranded RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

431367

SRC
Proto-oncogene tyrosine-protein kinase Src

1

13

Small-scale

0.618

High

533124

CD14
Monocyte differentiation antigen CD14

1

20

Small-scale

0.618

High

945954

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

2

Small-scale

0.618

High

1221641

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

20

Small-scale

0.618

High

1223487

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

17

Small-scale

0.618

High

1408866

TLR3
Toll-like receptor 3

1

20

Small-scale

0.618

High

1408868

TBK1
Serine/threonine-protein kinase TBK1

1

7

Small-scale

0.618

High

1408869

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.618

High

999884

TRAF6
TNF receptor-associated factor 6

2

11

Small-scale

0.584

High

1282022

TCAM1
TIR domain-containing adapter molecule 1

2

9

Small-scale

0.584

High

1353893

UN93B
Protein unc-93 homolog B1

2

7

Small-scale

0.584

High

398925

CFAD
Complement factor D

1

7

High-throughput

0.553

High

1224681

CD33
Myeloid cell surface antigen CD33

1

20

Small-scale

0.553

High

583153

IRF1
Interferon regulatory factor 1

1

13

Small-scale

0.479

High

595258

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

3

High-throughput

0.479

High

663332

IRF2
Interferon regulatory factor 2

1

13

Small-scale

0.479

High

1296818

TCAM2
TIR domain-containing adapter molecule 2

1

8

Small-scale

0.479

High

1317136

I17RD
Interleukin-17 receptor D

1

1

Small-scale

0.479

High

1317612

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.479

High

1408771

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

3

Small-scale

0.479

High

1408870

AIRE
Autoimmune regulator

1

8

Small-scale

0.479

High

1298404

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

0

Small-scale

0.458

High

1408867

Q9DAD3
WD repeat and FYVE domain containing 1

1

2

Small-scale

0.437

High


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Last updated: 11Aug2025