HitPredict

Interactor 1: HLAE (P13747)
HLA class I histocompatibility antigen, alpha chain E (MHC class I antigen E) [Cleaved into: Soluble HLA class I histocompatibility antigen, alpha chain E (sHLA-E)]
Gene: HLA-E

Interactor 2: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 18083576
Identification Methods surface plasmon resonance
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~Lectin_C, Lectin_C~MHC_I
Common GO terms GO:0002250 - adaptive immune response
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane
GO:0045087 - innate immune response
GO:0045953 - negative regulation of natural killer cell mediated cytotoxicity
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 358
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024