HitPredict

Interactor 1: IRF2 (P23906)
Interferon regulatory factor 2 (IRF-2)
Gene: IRF2

Interactor 2: TLR3 (Q99MB1)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12672806
Identification Methods	electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0034138 - toll-like receptor 3 signaling pathway GO:0051607 - defense response to virus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 349 Mm			1 905
+	Mm
		663333 IRF2_MOUSE (1-349): 0: 525: 100.00		TLR9_MOUSE (7-904): 9.6e-95: 322: 20.80
+	Mm
		583153 IRF1_MOUSE (1-288): 1.19e-109: 324: 42.91		TLR3_MOUSE (1-905): 3.04e-143: 449: 100.00
+	Mm
		583155 IRF1_MOUSE (1-288): 1.19e-109: 324: 42.91		TLR9_MOUSE (7-904): 9.6e-95: 322: 20.80
+	Hs
		191203 IRF2_HUMAN (1-349): 0: 510: 92.55		TLR3_HUMAN (5-190): 1.26e-12: 74.1: 20.69
+	Mm
		1225445 IRF4_MOUSE (7-146): 1.9e-66: 217: 41.43		TLR4_MOUSE (64-905): 1.16e-90: 307: 19.27
+	Mm
		661096 IRF8_MOUSE (7-125): 2.17e-59: 198: 47.06		TLR9_MOUSE (7-904): 9.6e-95: 322: 20.80
+	Mm
		661108 IRF8_MOUSE (7-125): 2.17e-59: 198: 47.06		TLR4_MOUSE (64-905): 1.16e-90: 307: 19.27
+	Hs
		191199 IRF1_HUMAN (1-265): 3.04e-103: 308: 44.73		TLR3_HUMAN (5-190): 1.26e-12: 74.1: 20.69
+	Mm
		660998 IRF8_MOUSE (7-125): 2.17e-59: 198: 47.06		TLR13_MOUSE (1-414): 9.74e-36: 148: 20.27
+	Hs
		252350 IRF3_HUMAN (1-146): 4.82e-52: 179: 31.97		TLR2_HUMAN (3-616): 2.78e-39: 158: 17.58
+	Hs
		126312 IRF4_HUMAN (7-145): 2.96e-63: 209: 41.01		TLR4_HUMAN (7-216): 7.35e-21: 100: 20.74
+	Hs
		126305 IRF8_HUMAN (7-139): 5.74e-59: 197: 41.48		TLR4_HUMAN (7-216): 7.35e-21: 100: 20.74
+	Hs
		191209 IRF8_HUMAN (7-139): 5.74e-59: 197: 41.48		TLR3_HUMAN (5-190): 1.26e-12: 74.1: 20.69