Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1
Interactor 2: TLR3 (Q99MB1)
Toll-like receptor 3 (CD antigen CD283)
Gene: TLR3
Species: Mus musculus
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12672806 |
| Identification Methods | electrophoretic mobility supershift assay |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0032481 - positive regulation of type I interferon production GO:0032728 - positive regulation of interferon-beta production GO:0032735 - positive regulation of interleukin-12 production GO:0034138 - toll-like receptor 3 signaling pathway GO:0035458 - cellular response to interferon-beta and 3 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025