Protein: ESC2
Protein ESC2 (Establishes silent chromatin protein 2)

Gene: ESC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 24
UniProt ID: Q06340

Gene Ontology (top 5):
GO:0000400 - four-way junction DNA binding
GO:0000403 - Y-form DNA binding
GO:0000724 - double-strand break repair via homologous recombination
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

897513

UBC9
SUMO-conjugating enzyme UBC9

3

0

Small-scale

0.806

High

1054893

SMT3
Ubiquitin-like protein SMT3

2

0

Small-scale

0.715

High

444800

SIR2
NAD-dependent histone deacetylase SIR2

3

0

Small-scale

0.617

High

1054346

MMS1
E3 ubiquitin-protein ligase linker protein MMS1

1

0

Small-scale

0.565

High

796777

MMS4
Crossover junction endonuclease MMS4

1

0

Small-scale

0.537

High

864613

CUL8
Cullin-8

1

0

Small-scale

0.525

High

557774

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.504

High

1035110

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.494

High

560248

TOP3
DNA topoisomerase 3

1

0

Small-scale

0.480

High

745501

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

Small-scale

0.480

High

763297

SGS1
ATP-dependent helicase SGS1

1

0

Small-scale

0.480

High

1045065

MUS81
Crossover junction endonuclease MUS81

1

0

Small-scale

0.480

High

1054891

ELG1
Telomere length regulation protein ELG1

1

0

Small-scale

0.480

High

793409

ATM
Serine/threonine-protein kinase TEL1

1

0

Small-scale

0.460

High

865756

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

1054892

RPN5
26S proteasome regulatory subunit RPN5

1

0

Small-scale

0.458

High

525234

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527745

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

546376

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

742459

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

742954

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

819868

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

816420

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.426

High

1051702

BSC2
Bypass of stop codon protein 2

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025