Protein: MMS1
E3 ubiquitin-protein ligase linker protein MMS1 (Methyl methanesulfonate-sensitivity protein 1) (Regulator of Ty1 transposition protein 108) (Synthetically lethal with MCM10 protein 6)

Gene: MMS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 58
UniProt ID: Q06211

Gene Ontology (top 5):
GO:0000725 - recombinational repair
GO:0005634 - nucleus
GO:0006275 - regulation of DNA replication
GO:0006334 - nucleosome assembly
GO:0010526 - transposable element silencing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

864612

CUL8
Cullin-8

5

0

Small-scale

0.682

High

1054350

RBX1
RING-box protein HRT1

4

0

Small-scale

0.652

High

805990

RT107
Regulator of Ty1 transposition protein 107

3

0

Small-scale

0.630

High

1053967

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

3

0

Small-scale

0.628

High

722273

XPO1
Exportin-1

2

0

Small-scale

0.588

High

574818

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

2

0

High-throughput

0.576

High

898174

ORC5
Origin recognition complex subunit 5

1

0

Small-scale

0.565

High

1054346

ESC2
Protein ESC2

1

0

Small-scale

0.565

High

1054349

CRT10
Protein CRT10

2

0

Small-scale

0.559

High

1030401

CTF4
DNA polymerase alpha-binding protein

1

0

Small-scale

0.513

High

1036133

PVH1
Tyrosine-protein phosphatase YVH1

1

0

High-throughput

0.513

High

359072

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.493

High

557773

SRS2
ATP-dependent DNA helicase SRS2

1

0

Small-scale

0.460

High

435372

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

708237

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

748053

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

792258

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.458

High

798619

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

800273

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.458

High

820395

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.458

High

916886

RTF1
RNA polymerase-associated protein RTF1

1

0

Small-scale

0.458

High

1018326

CTR9
RNA polymerase-associated protein CTR9

1

0

Small-scale

0.458

High

1044307

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

1044759

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1054347

CDC73
Cell division control protein 73

1

0

Small-scale

0.458

High

1054352

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1054353

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

481768

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

525218

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

527732

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

546357

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

742446

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

811497

XDJ1
DnaJ protein homolog XDJ1

1

1

High-throughput

0.445

High

819853

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

925071

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

393364

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

806997

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

0

High-throughput

0.426

High

417180

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.269

Low

410346

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433858

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

442120

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

455272

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

503251

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504424

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

513228

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

514844

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

514956

YA11A
Transposon Ty1-A Gag polyprotein

1

0

High-throughput

0.249

Low

674846

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.249

Low

747586

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

778541

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

802395

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

874537

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

1033576

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1046934

POB3
FACT complex subunit POB3

1

0

High-throughput

0.249

Low

1054348

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

1054351

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

816415

HSP7E
Heat shock protein SSC3, mitochondrial

1

0

High-throughput

0.232

Low

826493

DJP1
DnaJ-like protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025