Protein: ERG7
Lanosterol synthase ERG7 (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase ERG7) (Ergosterol biosynthetic protein 7) (Oxidosqualene--lanosterol cyclase ERG7) (OSC)

Gene: ERG7
Organism: Saccharomyces cerevisiae S288C
Interactions: 24
UniProt ID: P38604

Gene Ontology (top 5):
GO:0000250 - lanosterol synthase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005811 - lipid droplet
GO:0006696 - ergosterol biosynthetic process
GO:0016104 - triterpenoid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

800443

ERG7
Lanosterol synthase ERG7

2

1

High-throughput

0.791

High

800453

ERG27
3-keto-steroid reductase ERG27

5

0

Small-scale

0.684

High

800445

ERG28
Ergosterol biosynthetic protein 28

2

0

Small-scale

0.588

High

735334

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

1

Small-scale

0.541

High

757610

TGL1
Sterol esterase TGL1

1

1

High-throughput

0.541

High

800447

ERG25
C-4 methylsterol oxidase ERG25

1

1

Small-scale

0.541

High

800451

YEH1
Sterol esterase 1

1

1

High-throughput

0.541

High

528582

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

Small-scale

0.518

High

668906

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

Small-scale

0.518

High

702307

MGLL
Monoglyceride lipase

1

0

High-throughput

0.518

High

751694

PLSC
1-acyl-sn-glycerol-3-phosphate acyltransferase

1

0

High-throughput

0.518

High

763670

RER2
Dehydrodolichyl diphosphate synthase complex subunit RER2

1

0

High-throughput

0.518

High

796232

FAT1
Very long-chain fatty acid transport protein

1

0

High-throughput

0.518

High

797544

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

High-throughput

0.518

High

800448

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

1

0

Small-scale

0.518

High

800449

ERG5
C-22 sterol desaturase ERG5

1

0

Small-scale

0.518

High

800450

LEC1
PX domain-containing protein LEC1

1

0

Small-scale

0.460

High

571828

SNA3
Protein SNA3

1

0

High-throughput

0.282

High

793127

YRO2
Protein YRO2

1

0

High-throughput

0.282

High

800452

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.282

High

670647

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

800444

MET30
F-box protein MET30

1

0

High-throughput

0.238

Low

800446

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025