Protein: SDS3
Transcriptional regulatory protein SDS3 (Suppressor of defective silencing protein 3)

Gene: SDS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 38
UniProt ID: P40505

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006334 - nucleosome assembly
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

739882

RPD3
Histone deacetylase RPD3

13

0

Small-scale

0.929

High

649974

SIN3
Transcriptional regulatory protein SIN3

12

0

Small-scale

0.926

High

825603

PHO23
Transcriptional regulatory protein PHO23

5

0

Small-scale

0.877

High

796747

RXT2
Transcriptional regulatory protein RXT2

5

0

Small-scale

0.861

High

799722

SAP30
Transcriptional regulatory protein SAP30

4

0

Small-scale

0.846

High

726269

DEP1
Transcriptional regulatory protein DEP1

3

0

Small-scale

0.803

High

825613

CTI6
Histone deacetylase complex subunit CTI6

5

0

Small-scale

0.679

High

808833

UME6
Transcriptional regulatory protein UME6

4

0

Small-scale

0.653

High

825610

RXT3
Transcriptional regulatory protein RXT3

3

0

High-throughput

0.634

High

758064

ASH1
Transcriptional regulatory protein ASH1

3

0

Small-scale

0.606

High

825605

UME1
Transcriptional regulatory protein UME1

2

0

High-throughput

0.585

High

585957

CSK21
Casein kinase II subunit alpha

1

1

High-throughput

0.536

High

545147

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

825602

SNX4
Sorting nexin-4

1

0

Small-scale

0.518

High

825614

STB3
Protein STB3

1

0

Small-scale

0.493

High

825608

ATG17
Autophagy-related protein 17

1

0

High-throughput

0.486

High

602500

PHO85
Cyclin-dependent protein kinase PHO85

1

0

High-throughput

0.480

High

778903

NNK1
Nitrogen network kinase 1

1

0

High-throughput

0.480

High

757788

TOD6
Transcriptional regulatory protein TOD6

1

1

Small-scale

0.479

High

817677

DOT6
Transcriptional regulatory protein DOT6

1

1

Small-scale

0.479

High

816992

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.460

High

707307

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

734433

BTAF1
TATA-binding protein-associated factor MOT1

1

0

Small-scale

0.458

High

740950

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

763911

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

825604

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

825607

TOS4
Protein TOS4

1

0

High-throughput

0.458

High

678325

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.438

High

743465

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.438

High

794270

CHK1
Serine/threonine-protein kinase CHK1

1

0

High-throughput

0.438

High

809264

MET30
F-box protein MET30

1

0

High-throughput

0.438

High

741725

HSP7F
Heat shock protein homolog SSE1

1

0

High-throughput

0.426

High

825606

DHR1
Probable ATP-dependent RNA helicase DHR1

2

0

High-throughput

0.324

High

825601

CSK2B
Casein kinase II subunit beta

1

0

High-throughput

0.279

Low

825600

TOS3
Serine/threonine-protein kinase TOS3

1

0

High-throughput

0.261

Low

825609

YL352
F-box protein YLR352W

1

0

High-throughput

0.249

Low

825611

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

825612

SOG2
Leucine-rich repeat-containing protein SOG2

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025