Protein: TOS3
Serine/threonine-protein kinase TOS3 (EC 2.7.11.1) (Target of SBF protein 3)

Gene: TOS3
Organism: Saccharomyces cerevisiae S288C
Interactions: 97
UniProt ID: P43637

Gene Ontology (top 5):
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005777 - peroxisome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

548910

SCH9
Serine/threonine-protein kinase SCH9

1

12

High-throughput

0.647

High

697384

MIG1
Regulatory protein MIG1

1

2

High-throughput

0.647

High

743997

RAD23
UV excision repair protein RAD23

1

8

High-throughput

0.647

High

850981

ENV7
Serine/threonine-protein kinase ENV7

1

19

High-throughput

0.647

High

850982

ARP8
Actin-like protein ARP8

1

3

High-throughput

0.647

High

803199

RIM4
Meiotic activator RIM4

1

0

High-throughput

0.614

High

850959

CRZ1
Transcriptional regulator CRZ1

1

0

High-throughput

0.614

High

850979

THTR
Thiosulfate sulfurtransferase TUM1

1

0

High-throughput

0.614

High

579616

HSC82
ATP-dependent molecular chaperone HSC82

1

15

High-throughput

0.575

High

676106

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.575

High

850945

BUD4
Bud site selection protein 4

1

0

High-throughput

0.541

High

557013

AAKG
5'-AMP-activated protein kinase subunit gamma

1

11

High-throughput

0.536

High

850964

COFI
Cofilin

1

5

High-throughput

0.536

High

823269

JEM1
DnaJ-like chaperone JEM1

1

2

High-throughput

0.514

High

782671

ESL2
EST/SMG-like protein 2

1

0

High-throughput

0.513

High

504592

YH11A
Transposon Ty1-H Gag polyprotein

1

1

High-throughput

0.501

High

663777

PEX1
Peroxisomal ATPase PEX1

1

4

High-throughput

0.501

High

740304

PAH1
Phosphatidic acid phosphohydrolase 1

1

1

High-throughput

0.501

High

780962

SPC42
Spindle pole body component SPC42

1

1

High-throughput

0.501

High

782305

RNZ
Ribonuclease Z

1

1

High-throughput

0.501

High

802793

OSH3
Oxysterol-binding protein homolog 3

1

2

High-throughput

0.501

High

824465

6P21
6-phosphofructo-2-kinase 1

1

1

High-throughput

0.501

High

824685

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.501

High

850944

ALY2
Arrestin-related trafficking adapter 3

1

2

High-throughput

0.501

High

850948

GYP3
GTPase-activating protein GYP3

1

1

High-throughput

0.501

High

850949

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

High-throughput

0.501

High

850952

SDS23
Protein SDS23

1

11

High-throughput

0.501

High

850962

FOX2
Peroxisomal hydratase-dehydrogenase-epimerase

1

1

High-throughput

0.501

High

850965

YM11A
Transposon Ty1-ML1 Gag polyprotein

1

1

High-throughput

0.501

High

850971

DBP9
ATP-dependent RNA helicase DBP9

1

1

High-throughput

0.501

High

850973

BDF2
Bromodomain-containing factor 2

1

1

High-throughput

0.501

High

416454

HXKA
Hexokinase-1

1

1

High-throughput

0.500

High

470190

MET2
Homoserine O-acetyltransferase

1

0

High-throughput

0.480

High

584450

IDI1
Isopentenyl-diphosphate delta-isomerase

1

0

High-throughput

0.480

High

599043

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.480

High

624465

RDS2
Regulator of drug sensitivity 2

1

0

High-throughput

0.480

High

694224

BUD14
Bud site selection protein 14

1

0

High-throughput

0.480

High

733667

GLNA
Glutamine synthetase

1

0

High-throughput

0.480

High

746640

DRS1
ATP-dependent RNA helicase DRS1

1

0

High-throughput

0.480

High

763536

ATG19
Autophagy-related protein 19

1

0

High-throughput

0.480

High

779999

POC2
Proteasome assembly chaperone 2

1

0

High-throughput

0.480

High

782264

DRE2
Fe-S cluster assembly protein DRE2

1

0

High-throughput

0.480

High

782653

PXL1
Paxillin-like protein 1

1

0

High-throughput

0.480

High

805862

ARO9
Aromatic amino acid aminotransferase 2

1

0

High-throughput

0.480

High

809348

STM1
Suppressor protein STM1

1

0

High-throughput

0.480

High

820878

SIP5
Protein SIP5

1

0

High-throughput

0.480

High

850943

IDS2
IME2-dependent-signaling protein

1

0

High-throughput

0.480

High

850946

YJ9S
Uncharacterized protein YJR154W

1

0

High-throughput

0.480

High

850954

YG36
Uncharacterized protein YGR126W

1

0

High-throughput

0.480

High

850963

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.480

High

850967

KYNU
Kynureninase

1

0

High-throughput

0.480

High

850968

RGC1
Regulator of the glycerol channel 1

1

0

High-throughput

0.480

High

850970

YL257
Uncharacterized protein YLR257W

1

0

High-throughput

0.480

High

850972

MDM36
Mitochondrial distribution and morphology protein 36

1

0

High-throughput

0.480

High

850974

IWR1
RNA polymerase II nuclear localization protein IWR1

1

0

High-throughput

0.480

High

850980

SELO
Protein adenylyltransferase SelO, mitochondrial

1

0

High-throughput

0.480

High

850983

STB3
Protein STB3

1

0

High-throughput

0.480

High

850976

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.479

High

644636

MDHC
Malate dehydrogenase, cytoplasmic

1

0

High-throughput

0.458

High

661421

PSA3
Proteasome subunit alpha type-3

1

4

High-throughput

0.457

High

737095

CDC11
Cell division control protein 11

1

2

High-throughput

0.457

High

740732

SRP40
Suppressor protein SRP40

1

1

High-throughput

0.457

High

805127

YNG2
Chromatin modification-related protein YNG2

1

1

High-throughput

0.457

High

826425

AIM21
Altered inheritance of mitochondria protein 21

1

2

High-throughput

0.457

High

850413

ATG18
Autophagy-related protein 18

1

1

High-throughput

0.457

High

850953

ORM1
Protein ORM1

1

1

High-throughput

0.457

High

850957

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

4

High-throughput

0.457

High

850960

HDA1
Histone deacetylase HDA1

1

9

High-throughput

0.457

High

850961

CTF4
DNA polymerase alpha-binding protein

1

3

High-throughput

0.457

High

850969

ORM2
Protein ORM2

1

1

High-throughput

0.457

High

524338

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

527003

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

545326

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

741832

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

819086

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

464513

CHS1
Chitin synthase 1

1

0

High-throughput

0.261

Low

609227

CLC1
Clathrin light chain

1

0

High-throughput

0.261

Low

610168

PDI
Protein disulfide-isomerase

1

0

High-throughput

0.261

Low

617965

DAP2
Dipeptidyl aminopeptidase B

1

0

High-throughput

0.261

Low

659156

MBR1
Mitochondrial biogenesis regulation protein 1

1

0

High-throughput

0.261

Low

734336

DGR2
2-deoxy-glucose resistant protein 2

1

0

High-throughput

0.261

Low

738004

ISF1
Increasing suppression factor 1

1

0

High-throughput

0.261

Low

807236

SPT8
SAGA complex subunit SPT8

1

0

High-throughput

0.261

Low

815411

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.261

Low

817473

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

High-throughput

0.261

Low

825531

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.261

Low

825600

SDS3
Transcriptional regulatory protein SDS3

1

0

High-throughput

0.261

Low

850947

YG3O
Uncharacterized protein YGR153W

1

0

High-throughput

0.261

Low

850951

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.261

Low

850955

REXO1
RNA exonuclease 1

1

0

High-throughput

0.261

Low

850956

SUN4
Probable secreted beta-glucosidase SUN4

1

0

High-throughput

0.261

Low

850958

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.261

Low

850966

IVY1
Protein IVY1

1

0

High-throughput

0.261

Low

850975

YL030
Putative uncharacterized protein YLR030W

1

0

High-throughput

0.261

Low

850977

THP1
Nuclear mRNA export protein THP1

1

0

High-throughput

0.261

Low

850978

ALR1
Magnesium transporter ALR1

1

0

High-throughput

0.261

Low

850950

NUP84
Nucleoporin NUP84

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025