Protein: CSK2B
Casein kinase II subunit beta (CK II beta)

Gene: CSK2B, CKB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 151
UniProt ID: P43639

Gene Ontology (top 5):
GO:0000028 - ribosomal small subunit assembly
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005956 - protein kinase CK2 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

585969

CSK21
Casein kinase II subunit alpha

16

16

Small-scale

0.986

High

622974

CSK22
Casein kinase II subunit alpha'

15

17

Small-scale

0.985

High

807771

CSK2C
Casein kinase II subunit beta'

9

9

Small-scale

0.974

High

850999

UTP22
U3 small nucleolar RNA-associated protein 22

6

1

High-throughput

0.735

High

382177

H4
Histone H4

5

1

High-throughput

0.709

High

850994

CSK2B
Casein kinase II subunit beta

1

9

High-throughput

0.698

High

748862

SWE1
Mitosis inhibitor protein kinase SWE1

1

8

High-throughput

0.691

High

851027

HRK1
Serine/threonine-protein kinase HRK1

1

1

High-throughput

0.691

High

739674

SPT16
FACT complex subunit SPT16

10

3

Small-scale

0.688

High

812158

IFH1
Protein IFH1

4

1

Small-scale

0.674

High

744314

CHD1
Chromo domain-containing protein 1

5

4

Small-scale

0.657

High

808621

SAK1
SNF1-activating kinase 1

1

0

High-throughput

0.656

High

470144

SPS1
Sporulation-specific protein 1

1

5

High-throughput

0.647

High

548911

SCH9
Serine/threonine-protein kinase SCH9

1

9

High-throughput

0.647

High

560613

KIN1
Serine/threonine protein kinase KIN1

1

1

High-throughput

0.647

High

642412

MCK1
Protein kinase MCK1

1

1

High-throughput

0.647

High

735266

KNS1
Dual specificity protein kinase KNS1

1

3

Small-scale

0.647

High

851012

STE20
Serine/threonine-protein kinase STE20

1

7

High-throughput

0.647

High

851015

POB3
FACT complex subunit POB3

5

3

Small-scale

0.642

High

851011

HOT1
High-osmolarity-induced transcription protein 1

4

1

High-throughput

0.636

High

851035

RRP36
rRNA biogenesis protein RRP36

2

1

Small-scale

0.633

High

646445

RAD53
Serine/threonine-protein kinase RAD53

1

1

High-throughput

0.618

High

673194

RRP7
Ribosomal RNA-processing protein 7

2

1

High-throughput

0.614

High

796595

EIF3A
Eukaryotic translation initiation factor 3 subunit A

2

3

Small-scale

0.611

High

851032

RIO1
Serine/threonine-protein kinase RIO1

2

4

High-throughput

0.611

High

850997

ART5
Arrestin-related trafficking adapter 5

2

0

High-throughput

0.598

High

851018

SVF1
Ceramide-binding protein SVF1

2

1

Small-scale

0.595

High

780375

ELF1
Transcription elongation factor 1

3

1

Small-scale

0.594

High

557014

AAKG
5'-AMP-activated protein kinase subunit gamma

2

1

High-throughput

0.588

High

851005

H3
Histone H3

2

6

High-throughput

0.588

High

810650

SSN3
Meiotic mRNA stability protein kinase SSN3

1

3

High-throughput

0.579

High

822994

ATAD2
ATPase histone chaperone YTA7

3

4

Small-scale

0.578

High

805772

YHT1
PH domain-containing protein YHR131C

2

1

High-throughput

0.571

High

661174

SPT6
Transcription elongation factor SPT6

2

1

High-throughput

0.567

High

851006

CTR9
RNA polymerase-associated protein CTR9

2

3

High-throughput

0.567

High

561491

TBP
TATA-box-binding protein

1

1

Small-scale

0.561

High

449419

SPT2
Protein SPT2

2

1

Small-scale

0.558

High

851020

FKBP4
FK506-binding protein 4

2

2

High-throughput

0.552

High

851028

AP3D
AP-3 complex subunit delta

2

1

High-throughput

0.549

High

392933

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.541

High

632695

DBP4
ATP-dependent RNA helicase HCA4

1

2

High-throughput

0.541

High

747023

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

1

High-throughput

0.541

High

817586

UTP7
U3 small nucleolar RNA-associated protein 7

1

1

High-throughput

0.541

High

851014

UTP15
U3 small nucleolar RNA-associated protein 15

1

2

High-throughput

0.541

High

851019

UTP21
U3 small nucleolar RNA-associated protein 21

1

1

High-throughput

0.541

High

808379

SEC31
Protein transport protein SEC31

2

2

High-throughput

0.537

High

722042

XPO1
Exportin-1

1

3

High-throughput

0.536

High

738397

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

2

High-throughput

0.536

High

815822

BEM2
GTPase-activating protein BEM2/IPL2

1

3

High-throughput

0.536

High

820372

RIO2
Serine/threonine-protein kinase RIO2

1

4

High-throughput

0.536

High

823348

UTP18
U3 small nucleolar RNA-associated protein 18

1

1

High-throughput

0.536

High

851022

ESF1
Pre-rRNA-processing protein ESF1

1

1

High-throughput

0.536

High

777071

BDF1
Bromodomain-containing factor 1

2

10

Small-scale

0.533

High

826605

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

381149

H2B1
Histone H2B.1

2

3

High-throughput

0.521

High

677457

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.518

High

758381

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.518

High

779135

DHR2
Probable ATP-dependent RNA helicase DHR2

1

0

High-throughput

0.518

High

850998

SLX9
Ribosome biogenesis protein SLX9

1

0

High-throughput

0.518

High

851000

NOP19
Nucleolar protein 19

1

0

High-throughput

0.518

High

851003

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.518

High

851010

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.518

High

851017

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.518

High

851023

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.518

High

780615

CAB3
Coenzyme A biosynthesis protein 3

1

1

High-throughput

0.515

High

800718

RCK1
Serine/threonine-protein kinase RCK1

1

2

High-throughput

0.514

High

830131

NOP2
25S rRNA

1

0

High-throughput

0.513

High

851001

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

851008

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

570809

ABF1
ARS-binding factor 1

1

1

Small-scale

0.512

High

438455

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

1

High-throughput

0.489

High

448982

TOP2
DNA topoisomerase 2

1

2

High-throughput

0.489

High

824984

FKH1
Fork head protein homolog 1

1

3

High-throughput

0.489

High

851024

CDC73
Cell division control protein 73

1

1

High-throughput

0.489

High

851025

PSR2
Probable phosphatase PSR2

1

1

High-throughput

0.489

High

806303

KOG1
Target of rapamycin complex 1 subunit KOG1

1

1

High-throughput

0.481

High

149828

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.479

High

436450

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

579617

HSC82
ATP-dependent molecular chaperone HSC82

1

3

High-throughput

0.479

High

708756

TF3B
Transcription factor IIIB 70 kDa subunit

1

2

Small-scale

0.479

High

795422

ATG8
Autophagy-related protein 8

1

2

High-throughput

0.479

High

798248

ENP1
Essential nuclear protein 1

1

1

High-throughput

0.479

High

804851

NMD2
Nonsense-mediated mRNA decay protein 2

1

1

Small-scale

0.479

High

844506

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

851004

ORC1
Origin recognition complex subunit 1

1

4

High-throughput

0.479

High

851013

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

851029

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

851034

DBP10
ATP-dependent RNA helicase DBP10

1

2

High-throughput

0.479

High

383764

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

435178

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

436030

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

455125

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

512506

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

514694

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

689526

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

778392

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

802240

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

815937

PP2C2
Protein phosphatase 2C homolog 2

1

0

Small-scale

0.458

High

851009

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

851026

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.458

High

851030

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

524340

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

527005

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

545328

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

670860

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

743245

PP12
Serine/threonine-protein phosphatase PP1-2

1

4

High-throughput

0.445

High

781757

SET3
SET domain-containing protein 3

1

4

High-throughput

0.445

High

806968

2A5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

1

3

High-throughput

0.445

High

807096

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

2

High-throughput

0.445

High

819088

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

534065

HSF
Heat shock transcription factor

1

1

Small-scale

0.439

High

851033

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.439

High

851002

YNX4
Uncharacterized globin-like protein YNL234W

1

0

High-throughput

0.438

High

381548

H2B2
Histone H2B.2

1

3

High-throughput

0.437

High

419450

H2A1
Histone H2A.1

1

1

High-throughput

0.437

High

419784

H2A2
Histone H2A.2

1

1

High-throughput

0.437

High

513078

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

694575

SPT5
Transcription elongation factor SPT5

1

1

High-throughput

0.437

High

707448

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

748447

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

763745

CENPC
Inner kinetochore subunit MIF2

1

1

Small-scale

0.437

High

764194

SPT23
Protein SPT23

1

5

Small-scale

0.437

High

779272

CENPA
Histone H3-like centromeric protein CSE4

1

6

High-throughput

0.437

High

807819

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

1

Small-scale

0.437

High

811623

YCFI
Metal resistance protein YCF1

1

1

Small-scale

0.437

High

812424

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

851016

SWR1
Helicase SWR1

1

4

High-throughput

0.437

High

851021

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

851031

PSH1
RING finger protein PSH1

1

1

Small-scale

0.437

High

736519

SFP1
Transcription factor SFP1

1

0

High-throughput

0.426

High

805945

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

1

0

High-throughput

0.426

High

671535

SWI4
Regulatory protein SWI4

1

3

High-throughput

0.407

High

736668

ASF1
Histone chaperone ASF1

1

1

High-throughput

0.407

High

850995

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

4

High-throughput

0.407

High

851036

H2AZ
Histone H2A.Z

1

2

High-throughput

0.407

High

649982

SIN3
Transcriptional regulatory protein SIN3

2

0

High-throughput

0.324

High

482044

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

0

High-throughput

0.279

Low

825601

SDS3
Transcriptional regulatory protein SDS3

1

0

High-throughput

0.279

Low

748298

SPT4
Transcription elongation factor SPT4

1

0

High-throughput

0.269

Low

824832

ATG32
Autophagy-related protein 32

1

0

Small-scale

0.269

Low

851007

RHO3
GTP-binding protein RHO3

1

0

High-throughput

0.265

Low

826385

MPH1
ATP-dependent DNA helicase MPH1

1

0

Small-scale

0.251

Low

410200

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

433707

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

503110

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504277

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

753439

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

795062

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

850996

TCB2
Tricalbin-2

1

0

High-throughput

0.238

Low

776410

MNR2
Manganese resistance protein MNR2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025