Protein: ENPP7
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (E-NPP 7) (NPP-7) (EC 3.1.4.12) (Alkaline sphingomyelin phosphodiesterase) (Intestinal alkaline sphingomyelinase) (Alk-SMase)

Gene: ENPP7
Organism: Homo sapiens
Interactions: 27
UniProt ID: Q6UWV6

Gene Ontology (top 5):
GO:0004767 - sphingomyelin phosphodiesterase activity
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0005902 - microvillus
GO:0006684 - sphingomyelin metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1248878

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

2

1

High-throughput

0.628

High

1248874

CD109
CD109 antigen

2

0

High-throughput

0.602

High

1063360

GOGA2
Golgin subfamily A member 2

2

0

High-throughput

0.580

High

1108572

TBB3
Tubulin beta-3 chain

2

2

High-throughput

0.574

High

1248881

TBB1
Tubulin beta-1 chain

2

2

High-throughput

0.574

High

1147482

RHEB
GTP-binding protein Rheb

1

1

High-throughput

0.536

High

1248883

MKS1
Tectonic-like complex member MKS1

1

1

High-throughput

0.536

High

1248886

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

1

High-throughput

0.536

High

600618

NAGAB
Alpha-N-acetylgalactosaminidase

1

0

High-throughput

0.513

High

932376

ANAG
Alpha-N-acetylglucosaminidase

1

0

High-throughput

0.513

High

1034759

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1143624

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.513

High

1248876

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.513

High

1248877

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

1248879

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

0

High-throughput

0.513

High

1248887

ORNT1
Mitochondrial ornithine transporter 1

1

0

High-throughput

0.513

High

1191848

TBB8
Tubulin beta-8 chain

1

2

High-throughput

0.489

High

1248328

PLGT2
Protein O-glucosyltransferase 2

1

1

High-throughput

0.489

High

1248875

PLGT3
Protein O-glucosyltransferase 3

1

1

High-throughput

0.489

High

1248884

EPDR1
Mammalian ependymin-related protein 1

2

0

High-throughput

0.328

High

685886

KRA59
Keratin-associated protein 5-9

2

0

High-throughput

0.316

High

1205834

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.316

High

1206664

LRC73
Leucine-rich repeat-containing protein 73

2

0

High-throughput

0.316

High

1248880

BACH2
Transcription regulator protein BACH2

2

0

High-throughput

0.316

High

566718

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.279

Low

1248882

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

1248885

RHG26
Rho GTPase-activating protein 26

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025