Protein: TBB1
Tubulin beta-1 chain

Gene: TBB1, TUBB1
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9H4B7

Gene Ontology (top 5):
GO:0000226 - microtubule cytoskeleton organization
GO:0000278 - mitotic cell cycle
GO:0003924 - GTPase activity
GO:0005200 - structural constituent of cytoskeleton
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1415112

TBB2B
Tubulin beta-2B chain

3

17

High-throughput

0.861

High

1108706

TBB3
Tubulin beta-3 chain

2

18

High-throughput

0.811

High

1118593

TBB2A
Tubulin beta-2A chain

2

17

High-throughput

0.776

High

457696

TBB5
Tubulin beta chain

1

17

High-throughput

0.691

High

610889

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.691

High

882158

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.691

High

997511

TBB4B
Tubulin beta-4B chain

1

17

High-throughput

0.691

High

369275

ANT3
Antithrombin-III

3

1

High-throughput

0.667

High

567983

PRG2
Bone marrow proteoglycan

3

8

High-throughput

0.667

High

1428911

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

3

5

High-throughput

0.667

High

1433425

TSP50
Probable threonine protease PRSS50

3

20

High-throughput

0.667

High

664937

CRHBP
Corticotropin-releasing factor-binding protein

3

0

High-throughput

0.638

High

1232381

SFRP4
Secreted frizzled-related protein 4

3

0

High-throughput

0.638

High

1233181

ASTL
Astacin-like metalloendopeptidase

3

0

High-throughput

0.638

High

144109

WNT7A
Protein Wnt-7a

2

4

High-throughput

0.628

High

1369263

RPGR
X-linked retinitis pigmentosa GTPase regulator

2

11

High-throughput

0.628

High

1433416

DOCK5
Dedicator of cytokinesis protein 5

2

1

High-throughput

0.628

High

1433426

CELA1
Chymotrypsin-like elastase family member 1

2

18

High-throughput

0.628

High

1433429

AAKB1
5'-AMP-activated protein kinase subunit beta-1

2

3

High-throughput

0.628

High

841584

I12R1
Interleukin-12 receptor subunit beta-1

1

9

High-throughput

0.618

High

1308403

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

20

High-throughput

0.618

High

1363698

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.618

High

655927

TBG1
Tubulin gamma-1 chain

1

18

High-throughput

0.618

High

996851

TBA1B
Tubulin alpha-1B chain

1

20

Small-scale

0.618

High

1115427

CUL4B
Cullin-4B

2

20

High-throughput

0.611

High

1307357

ZNG1B
Zinc-regulated GTPase metalloprotein activator 1B

2

2

High-throughput

0.611

High

1433423

CLC5A
C-type lectin domain family 5 member A

3

7

High-throughput

0.609

High

350740

NOE2
Noelin-2

2

0

High-throughput

0.602

High

155803

TXND9
Thioredoxin domain-containing protein 9

1

6

High-throughput

0.575

High

626363

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

20

High-throughput

0.575

High

192133

PA2GX
Group 10 secretory phospholipase A2

2

1

High-throughput

0.574

High

231813

MFS11
UNC93-like protein MFSD11

2

4

High-throughput

0.574

High

273785

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

2

6

High-throughput

0.574

High

361660

OTC
Ornithine transcarbamylase, mitochondrial

2

3

High-throughput

0.574

High

543438

PSG1
Pregnancy-specific beta-1-glycoprotein 1

2

5

High-throughput

0.574

High

615161

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

2

7

High-throughput

0.574

High

1111267

SNW1
SNW domain-containing protein 1

2

4

Small-scale

0.574

High

1248881

ENPP7
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

2

2

High-throughput

0.574

High

1324674

MUC20
Mucin-20

2

1

High-throughput

0.574

High

1330834

TSYL6
Testis-specific Y-encoded-like protein 6

2

3

High-throughput

0.574

High

1359155

GLMP
Glycosylated lysosomal membrane protein

2

6

High-throughput

0.574

High

1364796

RPGF5
Rap guanine nucleotide exchange factor 5

2

1

High-throughput

0.574

High

1406987

NPAS1
Neuronal PAS domain-containing protein 1

2

6

High-throughput

0.574

High

1433418

ACAD9
Complex I assembly factor ACAD9, mitochondrial

2

1

High-throughput

0.574

High

1433427

PSG8
Pregnancy-specific beta-1-glycoprotein 8

2

6

High-throughput

0.574

High

1433430

LIPG
Endothelial lipase

2

1

High-throughput

0.574

High

599225

IL7RA
Interleukin-7 receptor subunit alpha

1

6

High-throughput

0.553

High

259105

DNJA2
DnaJ homolog subfamily A member 2

1

18

High-throughput

0.536

High

420840

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

1

High-throughput

0.536

High

486617

TACD2
Tumor-associated calcium signal transducer 2

1

1

High-throughput

0.536

High

564365

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.536

High

909184

NEK4
Serine/threonine-protein kinase Nek4

1

19

High-throughput

0.536

High

946260

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

6

High-throughput

0.536

High

1034819

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

4

High-throughput

0.536

High

1098753

NDK3
Nucleoside diphosphate kinase 3

1

6

High-throughput

0.536

High

1112712

CUL1
Cullin-1

1

20

High-throughput

0.536

High

1114290

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1115058

CUL4A
Cullin-4A

1

20

High-throughput

0.536

High

1272563

CSN6
COP9 signalosome complex subunit 6

1

6

High-throughput

0.536

High

1291208

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

6

High-throughput

0.536

High

1333230

DTWD2
tRNA-uridine aminocarboxypropyltransferase 2

1

2

High-throughput

0.536

High

1334563

RN149
E3 ubiquitin-protein ligase RNF149

1

7

High-throughput

0.536

High

1352111

ATS17
A disintegrin and metalloproteinase with thrombospondin motifs 17

1

6

High-throughput

0.536

High

1356000

CLC4C
C-type lectin domain family 4 member C

1

6

High-throughput

0.536

High

1370375

CSN5
COP9 signalosome complex subunit 5

1

13

High-throughput

0.536

High

1428604

DNAI2
Dynein axonemal intermediate chain 2

1

20

High-throughput

0.536

High

1430473

RAB1B
Ras-related protein Rab-1B

1

4

High-throughput

0.536

High

1433421

T11L1
T-complex protein 11-like protein 1

1

12

High-throughput

0.536

High

1433431

USH1C
Harmonin

1

17

High-throughput

0.536

High

1433260

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

1

High-throughput

0.533

High

1280994

PXK
PX domain-containing protein kinase-like protein

1

14

High-throughput

0.515

High

1364769

PHYIP
Phytanoyl-CoA hydroxylase-interacting protein

1

0

High-throughput

0.513

High

1433417

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.513

High

1339461

TOIP2
Torsin-1A-interacting protein 2

2

2

High-throughput

0.504

High

721066

CLIP1
CAP-Gly domain-containing linker protein 1

1

7

Small-scale

0.501

High

231342

EFNA2
Ephrin-A2

1

15

High-throughput

0.489

High

273365

NPHP4
Nephrocystin-4

1

8

High-throughput

0.489

High

458023

TRY2
Trypsin-2

1

20

High-throughput

0.489

High

570717

EDN3
Endothelin-3

1

3

High-throughput

0.489

High

732945

GASR
Gastrin/cholecystokinin type B receptor

1

2

High-throughput

0.489

High

938540

CCL18
C-C motif chemokine 18

1

3

High-throughput

0.489

High

1022276

FBLN2
Fibulin-2

1

1

High-throughput

0.489

High

1112988

CUL2
Cullin-2

1

20

High-throughput

0.489

High

1119427

CAYP1
Calcyphosin

1

12

High-throughput

0.489

High

1209008

PPR29
Protein phosphatase 1 regulatory subunit 29

1

2

High-throughput

0.489

High

1329868

SIR6
NAD-dependent protein deacylase sirtuin-6

1

5

High-throughput

0.489

High

1371862

CUL5
Cullin-5

1

20

High-throughput

0.489

High

1399316

WFKN1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

1

4

High-throughput

0.489

High

1430417

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

2

High-throughput

0.489

High

1432112

KLK15
Kallikrein-15

1

20

High-throughput

0.489

High

156666

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

20

Small-scale

0.479

High

242922

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

316010

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

325111

HEXI1
Protein HEXIM1

1

8

High-throughput

0.479

High

396936

ESR1
Estrogen receptor

1

17

Small-scale

0.479

High

791728

SYUA
Alpha-synuclein

1

2

Small-scale

0.479

High

848077

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

2

High-throughput

0.479

High

862458

YAP1
Transcriptional coactivator YAP1

1

20

High-throughput

0.479

High

946202

MLF1
Myeloid leukemia factor 1

1

2

High-throughput

0.479

High

990726

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

1008883

RED1
Double-stranded RNA-specific editase 1

1

6

High-throughput

0.479

High

1098136

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

1127163

RBM39
RNA-binding protein 39

1

7

High-throughput

0.479

High

1153592

MLF2
Myeloid leukemia factor 2

1

2

High-throughput

0.479

High

1158541

CDC37
Hsp90 co-chaperone Cdc37

1

2

High-throughput

0.479

High

1218571

MYSM1
Deubiquitinase MYSM1

1

1

Small-scale

0.479

High

1349764

FBX25
F-box only protein 25

1

11

High-throughput

0.479

High

1389893

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

16

High-throughput

0.479

High

1410368

MEP50
Methylosome protein WDR77

1

15

High-throughput

0.479

High

1413486

AASD1
Alanyl-tRNA editing protein Aarsd1

1

2

High-throughput

0.479

High

1433415

EGLN3
Prolyl hydroxylase EGLN3

1

7

High-throughput

0.479

High

1433420

BRD7
Bromodomain-containing protein 7

1

9

High-throughput

0.479

High

141105

NOP56
Nucleolar protein 56

1

0

Small-scale

0.458

High

644051

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

Small-scale

0.458

High

1033944

SC6A3
Sodium-dependent dopamine transporter

1

0

Small-scale

0.458

High

1209656

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

15

Small-scale

0.457

High

170351

AURKA
Aurora kinase A

1

15

High-throughput

0.445

High

282490

KTNA1
Katanin p60 ATPase-containing subunit A1

1

20

High-throughput

0.445

High

328154

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

20

High-throughput

0.445

High

484223

PGFRB
Platelet-derived growth factor receptor beta

1

8

High-throughput

0.445

High

881309

FAS
Fatty acid synthase

1

3

High-throughput

0.445

High

935133

TERA
Transitional endoplasmic reticulum ATPase

1

9

High-throughput

0.445

High

952343

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

20

High-throughput

0.445

High

1028393

MDM2
E3 ubiquitin-protein ligase Mdm2

1

3

Small-scale

0.445

High

1093179

STK4
Serine/threonine-protein kinase 4

1

19

High-throughput

0.445

High

1119308

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

9

High-throughput

0.445

High

1315536

KATL2
Katanin p60 ATPase-containing subunit A-like 2

1

20

High-throughput

0.445

High

1341097

INADL
InaD-like protein

1

12

High-throughput

0.445

High

1415090

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

1

20

High-throughput

0.445

High

1415928

KATL1
Katanin p60 ATPase-containing subunit A-like 1

1

20

High-throughput

0.445

High

1428352

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

20

High-throughput

0.445

High

1430325

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

20

High-throughput

0.445

High

1433195

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

20

High-throughput

0.445

High

1433422

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

3

High-throughput

0.445

High

487750

PARP1
Poly [ADP-ribose] polymerase 1

1

3

Small-scale

0.437

High

911953

JAK3
Tyrosine-protein kinase JAK3

1

20

High-throughput

0.437

High

1086316

TFCP2
Alpha-globin transcription factor CP2

1

7

High-throughput

0.437

High

1194377

LARP7
La-related protein 7

1

11

High-throughput

0.437

High

1271859

MEPCE
7SK snRNA methylphosphate capping enzyme

1

8

High-throughput

0.437

High

1383406

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

4

Small-scale

0.437

High

1384534

Q96BE0
Heat shock cognate 71 kDa protein

1

11

High-throughput

0.437

High

1385866

CHM4C
Charged multivesicular body protein 4c

1

4

High-throughput

0.437

High

1388641

SPDLY
Protein Spindly

1

7

High-throughput

0.437

High

1433424

ZMYM2
Zinc finger MYM-type protein 2

1

7

Small-scale

0.437

High

1433428

AAR2
Protein AAR2 homolog

1

5

High-throughput

0.437

High

430356

JUN
Transcription factor Jun

1

13

High-throughput

0.407

High

754102

CD80
T-lymphocyte activation antigen CD80

1

7

High-throughput

0.407

High

1395662

S35E1
Solute carrier family 35 member E1

1

1

High-throughput

0.407

High

64611

KLH33
Kelch-like protein 33

2

0

High-throughput

0.328

High

488344

PPBI
Intestinal-type alkaline phosphatase

2

0

High-throughput

0.328

High

1179143

TECT1
Tectonic-1

2

0

High-throughput

0.328

High

1181050

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

1211302

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.279

Low

1279823

BTLA
B- and T-lymphocyte attenuator

1

0

High-throughput

0.279

Low

1390353

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.279

Low

1394148

IGS21
Immunoglobulin superfamily member 21

1

0

High-throughput

0.279

Low

1398205

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.279

Low

1411479

TM2D3
TM2 domain-containing protein 3

1

0

High-throughput

0.279

Low

1433419

COE2
Transcription factor COE2

1

0

High-throughput

0.279

Low

598558

UD2B7
UDP-glucuronosyltransferase 2B7

1

0

Small-scale

0.232

Low


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Last updated: 11Aug2025