Protein: CD109
CD109 antigen (150 kDa TGF-beta-1-binding protein) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7) (Platelet-specific Gov antigen) (p180) (r150) (CD antigen CD109)

Gene: CD109
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q6YHK3

Gene Ontology (top 5):
GO:0001942 - hair follicle development
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1251498

PRS33
Serine protease 33

2

1

High-throughput

0.811

High

663556

CMA1
Chymase

2

8

High-throughput

0.776

High

62199

PRS37
Probable inactive serine protease 37

1

12

High-throughput

0.691

High

609717

LEG3
Galectin-3

4

7

High-throughput

0.691

High

125509

LEG9
Galectin-9

3

7

High-throughput

0.667

High

1144620

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

3

1

High-throughput

0.667

High

351703

SG1D1
Secretoglobin family 1D member 1

3

4

High-throughput

0.662

High

457106

CAN1
Calpain-1 catalytic subunit

3

1

High-throughput

0.662

High

378290

IFN21
Interferon alpha-21

2

1

High-throughput

0.628

High

1251062

SG1D4
Secretoglobin family 1D member 4

2

4

High-throughput

0.628

High

1251492

IFNE
Interferon epsilon

2

1

High-throughput

0.628

High

467720

CEL2B
Chymotrypsin-like elastase family member 2B

1

2

High-throughput

0.618

High

1248874

ENPP7
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7

2

0

High-throughput

0.602

High

480837

LEG1
Galectin-1

2

7

High-throughput

0.601

High

1251522

FBX2
F-box only protein 2

2

4

High-throughput

0.601

High

321276

ERLN2
Erlin-2

2

0

High-throughput

0.585

High

268926

FCG3B
Low affinity immunoglobulin gamma Fc region receptor III-B

2

4

High-throughput

0.584

High

363454

EGFR
Epidermal growth factor receptor

2

4

Small-scale

0.584

High

1251515

ANLN
Anillin

2

2

High-throughput

0.584

High

757357

RNAS4
Ribonuclease 4

2

0

High-throughput

0.576

High

880027

DNSL1
Deoxyribonuclease-1-like 1

2

0

High-throughput

0.576

High

1251523

DKKL1
Dickkopf-like protein 1

2

0

High-throughput

0.576

High

469804

CATG
Cathepsin G

1

8

High-throughput

0.575

High

1153401

CD226
CD226 antigen

1

3

High-throughput

0.575

High

1251517

FBX6
F-box only protein 6

2

4

High-throughput

0.571

High

142220

CCL22
C-C motif chemokine 22

1

2

High-throughput

0.536

High

606009

CAN2
Calpain-2 catalytic subunit

1

1

High-throughput

0.536

High

772867

MYH9
Myosin-9

1

1

High-throughput

0.536

High

843128

CXCL5
C-X-C motif chemokine 5

1

1

High-throughput

0.536

High

1030790

DEF5
Defensin alpha 5

1

1

High-throughput

0.536

High

1117954

PKP1
Plakophilin-1

1

4

High-throughput

0.536

High

1251501

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

1

4

High-throughput

0.536

High

1251507

ASPP1
Apoptosis-stimulating of p53 protein 1

1

2

High-throughput

0.536

High

1251508

MMP19
Matrix metalloproteinase-19

1

2

High-throughput

0.536

High

1251526

HYOU1
Hypoxia up-regulated protein 1

1

3

High-throughput

0.536

High

416628

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.513

High

814752

PA2G5
Phospholipase A2 group V

1

0

High-throughput

0.513

High

1025927

NDP
Norrin

1

0

High-throughput

0.513

High

1120460

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1127311

EP3A
Epididymal secretory protein E3-alpha

1

0

High-throughput

0.513

High

1152117

MARE1
Microtubule-associated protein RP/EB family member 1

1

0

High-throughput

0.513

High

1165365

ODAPH
Odontogenesis associated phosphoprotein

1

0

High-throughput

0.513

High

1181045

DB135
Beta-defensin 135

1

0

High-throughput

0.513

High

1204556

NMS
Neuromedin-S

1

0

High-throughput

0.513

High

1249600

ALKL2
ALK and LTK ligand 2

1

0

High-throughput

0.513

High

1251493

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.513

High

1251494

TAFA2
Chemokine-like protein TAFA-2

1

0

High-throughput

0.513

High

1251495

SYNPO
Synaptopodin

1

0

High-throughput

0.513

High

1251503

UCN3
Urocortin-3

1

0

High-throughput

0.513

High

1251505

VMP1
Vacuole membrane protein 1

1

0

High-throughput

0.513

High

1251524

PCDGK
Protocadherin gamma-C3

1

0

High-throughput

0.513

High

547325

CP19A
Aromatase

1

2

High-throughput

0.489

High

698792

CALX
Calnexin

1

1

High-throughput

0.489

High

1205836

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

4

High-throughput

0.489

High

1244073

CXB7
Gap junction beta-7 protein

1

4

High-throughput

0.489

High

154836

ISLR
Immunoglobulin superfamily containing leucine-rich repeat protein

1

1

High-throughput

0.479

High

218356

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

410911

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

3

High-throughput

0.479

High

714210

PML
Protein PML

1

2

High-throughput

0.479

High

774444

BASI
Basigin

1

3

High-throughput

0.479

High

898241

R144A
E3 ubiquitin-protein ligase RNF144A

1

1

Small-scale

0.479

High

1035714

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

1137795

TNIP1
TNFAIP3-interacting protein 1

1

5

High-throughput

0.479

High

1163777

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

1

High-throughput

0.479

High

1251496

EMC5
ER membrane protein complex subunit 5

1

1

High-throughput

0.479

High

1251518

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

1251519

HDAC6
Protein deacetylase HDAC6

1

6

High-throughput

0.479

High

157528

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

1041670

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

0

Small-scale

0.458

High

1140453

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1204482

RNS13
Probable inactive ribonuclease-like protein 13

1

0

High-throughput

0.458

High

1251491

CASZ1
Zinc finger protein castor homolog 1

1

0

High-throughput

0.458

High

1251512

CHM4B
Charged multivesicular body protein 4b

1

0

High-throughput

0.458

High

1251513

ECT2
Protein ECT2

1

0

High-throughput

0.458

High

97130

E9PNY5
Fc gamma receptor IIIb

1

3

High-throughput

0.445

High

765642

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

839038

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

High-throughput

0.445

High

945894

INHBE
Inhibin beta E chain

1

6

High-throughput

0.445

High

976823

LCN6
Epididymal-specific lipocalin-6

1

3

High-throughput

0.445

High

1251510

ZDHC5
Palmitoyltransferase ZDHHC5

1

2

High-throughput

0.445

High

331069

KI20A
Kinesin-like protein KIF20A

1

2

High-throughput

0.437

High

372364

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.437

High

1251502

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

1251511

RNF38
E3 ubiquitin-protein ligase RNF38

1

6

Small-scale

0.437

High

1251521

SEPT9
Septin-9

1

1

Small-scale

0.437

High

222294

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.426

High

1251500

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.426

High

1251506

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

1251514

LRC4C
Leucine-rich repeat-containing protein 4C

1

0

High-throughput

0.426

High

1251520

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.426

High

1251525

PRG3
Proteoglycan 3

1

0

High-throughput

0.426

High

170828

CLGN
Calmegin

1

1

High-throughput

0.407

High

1160402

TAZ
Tafazzin

3

0

High-throughput

0.347

High

66622

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.279

Low

1224730

PLCX3
PI-PLC X domain-containing protein 3

1

0

High-throughput

0.279

Low

1251516

MYO5C
Unconventional myosin-Vc

1

0

High-throughput

0.279

Low

247971

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

571456

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

1136241

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

1251497

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.249

Low

1251499

T185A
Transmembrane protein 185A

1

0

High-throughput

0.249

Low

1251504

PLD4
5'-3' exonuclease PLD4

1

0

High-throughput

0.249

Low

1251509

ZBT18
Zinc finger and BTB domain-containing protein 18

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025