HitPredict

Interactor 1: ARF5 (P84085)
ADP-ribosylation factor 5
Gene: ARF5

Interactor 2: ARFG2 (Q8N6H7)
ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)
Gene: ARFGAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~ArfGap
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 180 Hs			1 521
+	Hs
		612263 ARF4_HUMAN (1-180): 1.12e-69: 210: 90.00		ARFG2_HUMAN (1-521): 3.39e-168: 487: 100.00
+	Hs
		1014924 ARF1_HUMAN (1-180): 3.32e-66: 202: 80.56		ARFG2_HUMAN (1-521): 3.39e-168: 487: 100.00
+	Hs
		958795 ARF3_HUMAN (1-180): 9.79e-66: 201: 78.89		ARFG2_HUMAN (1-521): 3.39e-168: 487: 100.00
+	Hs
		612312 ARF4_HUMAN (1-180): 1.12e-69: 210: 90.00		ARFG3_HUMAN (3-520): 6.09e-131: 392: 53.80
+	Hs
		1015129 ARF5_HUMAN (1-180): 5.54e-69: 209: 100.00		ARFG3_HUMAN (3-520): 6.09e-131: 392: 53.80
+	Hs
		1014966 ARF1_HUMAN (1-180): 3.32e-66: 202: 80.56		ARFG3_HUMAN (3-520): 6.09e-131: 392: 53.80
+	Hs
		975335 ARF6_HUMAN (5-179): 5e-74: 221: 64.00		GIT1_HUMAN (18-454): 3.32e-66: 229: 13.68
+	Sc
		536116 ARF1_YEAST (1-179): 4.32e-78: 232: 69.83		GLO3_YEAST (5-477): 5.31e-62: 212: 20.62
+	Sc
		536102 ARF1_YEAST (1-179): 4.32e-78: 232: 69.83		GCS1_YEAST (1-361): 5.75e-63: 211: 18.96
+	Hs
		975116 ARF6_HUMAN (5-179): 5e-74: 221: 64.00		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Hs
		1014985 ARF1_HUMAN (1-180): 3.32e-66: 202: 80.56		GIT1_HUMAN (18-454): 3.32e-66: 229: 13.68
+	Hs
		1014925 ARF1_HUMAN (1-180): 3.32e-66: 202: 80.56		ARFG1_HUMAN (6-387): 1.45e-62: 211: 21.66
+	Hs
		958793 ARF3_HUMAN (1-180): 9.79e-66: 201: 78.89		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Ce
		1457936 Q9U2S4_CAEEL (8-175): 1.08e-81: 241: 65.48		CNT1_CAEEL (12-217): 1.8e-44: 169: 24.16
+	Hs
		612270 ARF4_HUMAN (1-180): 1.12e-69: 210: 90.00		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		975040 ARF6_HUMAN (5-179): 5e-74: 221: 64.00		ACAP1_HUMAN (1-238): 1.59e-47: 177: 21.76
+	Hs
		975042 ARF6_HUMAN (5-179): 5e-74: 221: 64.00		ACAP2_HUMAN (2-250): 2.25e-47: 177: 19.05
+	At
		306660 ARF2B_ARATH (1-177): 3.74e-66: 201: 81.92		AGD7_ARATH (11-404): 4.35e-47: 171: 20.37
+	Hs
		975324 ARF6_HUMAN (5-179): 5e-74: 221: 64.00		AGAP1_HUMAN (6-136): 5.55e-36: 144: 27.48
+	Hs
		1014982 ARF1_HUMAN (1-180): 3.32e-66: 202: 80.56		AGAP1_HUMAN (6-136): 5.55e-36: 144: 27.48