Interactor 1: RRP6 (Q12149)
Exosome complex exonuclease RRP6 (Rrp6p) (EC 3.1.13.-) (Ribosomal RNA-processing protein 6)
Gene: RRP6

Interactor 2: RRP42 (Q12277)
Exosome complex component RRP42 (Ribosomal RNA-processing protein 42)
Gene: RRP42

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 16429126, 16829593, 37968396, 12837249, 27345150, 16554755, 28877463, 28539363, 29176610, 31662437, 19046973, 14759368
Identification Methods affinity chromatography technology, pull down, biochemical, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
and 9 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 733
Sc

1 265
+ Sc
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Sp
+ Dm
+ Pf

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Last updated: 15 Jul 2024