HitPredict

Interactor 1: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	28977666, 16169070
Identification Methods	affinity chromatography technology, two hybrid, two hybrid pooling approach
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0003682 - chromatin binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2000 Hs			1 915
+	Hs
		1018710 CHD3_HUMAN (1-2000): 0: 1917: 100.00		MDN1_HUMAN (63-707): 1.6e-64: 239: 11.64
+	Hs
		1018458 CHD3_HUMAN (1-2000): 0: 1917: 100.00		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		516483 CHD3_HUMAN (1-2000): 0: 1917: 100.00		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		1059632 CHD4_HUMAN (132-1922): 0: 1552: 69.84		SAFB1_HUMAN (1-915): 3.38e-116: 378: 100.00
+	Hs
		1059899 CHD4_HUMAN (132-1922): 0: 1552: 69.84		MDN1_HUMAN (63-707): 1.6e-64: 239: 11.64
+	Hs
		1031332 CHD4_HUMAN (132-1922): 0: 1552: 69.84		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		516522 CHD4_HUMAN (132-1922): 0: 1552: 69.84		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Hs
		151416 CHD1_HUMAN (507-1729): 0: 746: 29.81		SAFB1_HUMAN (1-915): 3.38e-116: 378: 100.00
+	Hs
		516702 CHD8_HUMAN (84-1804): 0: 851: 22.96		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51
+	Zm
		12052 A0A1D6FIP6_MAIZE (577-1626): 0: 781: 27.40		O48554_MAIZE (409-484): 1.66e-11: 64.9: 34.21