HitPredict

Interactor 1: SF3A3 (Q12874)
Splicing factor 3A subunit 3 (SF3a60) (Spliceosome-associated protein 61) (SAP 61)
Gene: SF3A3

Interactor 2: SF3B3 (Q15393)
Splicing factor 3B subunit 3 (Pre-mRNA-splicing factor SF3b 130 kDa subunit) (SF3b130) (STAF130) (Spliceosome-associated protein 130) (SAP 130)
Gene: SF3B3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.892

The method score is based on:

Property	Details
Experiments	24981860, 35271311, 30021884, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CPSF_A~SF3a60_Prp9_C
Common GO terms	GO:0000375 - RNA splicing, via transesterification reactions GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex and 5 others more... GO:0005684 - U2-type spliceosomal complex GO:0005686 - U2 snRNP GO:0071005 - U2-type precatalytic spliceosome GO:0071013 - catalytic step 2 spliceosome GO:1903241 - U2-type prespliceosome assembly
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	501
Hs

1	1217

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024