Interactor 1: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Interactor 2: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Guanylate_kin~PDZ, PDZ~PDZ, PH~SH3_1, RhoGEF~SH3_1
Common GO terms GO:0005829 - cytosol
GO:0005874 - microtubule
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0008284 - positive regulation of cell population proliferation
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 904
Hs

1 1591
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Last updated: 15 Jul 2024