HitPredict

Interactor 1: TSYL2 (Q9H2G4)
Testis-specific Y-encoded-like protein 2 (TSPY-like protein 2) (Cell division autoantigen 1) (Cutaneous T-cell lymphoma-associated antigen se20-4) (CTCL-associated antigen se20-4) (Differentially-expressed nucleolar TGF-beta1 target protein) (Nuclear protein of 79 kDa) (NP79)
Gene: TSPYL2

Interactor 2: U3KQK0 (U3KQK0)
Histone H2B
Gene: H2BC15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 693 Hs			1 166
+	Hs
		1407997 TSYL2_HUMAN (1-693): 6.15e-145: 440: 100.00		H2B1N_HUMAN (1-126): 1.1e-57: 178: 100.00
+	Hs
		754984 TSYL1_HUMAN (15-399): 2.12e-135: 407: 35.08		H2B1B_HUMAN (1-126): 8.04e-58: 178: 98.41
+	Hs
		754898 TSYL5_HUMAN (44-412): 1.12e-107: 334: 34.03		H2B1B_HUMAN (1-126): 8.04e-58: 178: 98.41
+	Hs
		1030936 TSPY1_HUMAN (127-403): 8.14e-69: 229: 33.33		H2B2E_HUMAN (1-126): 3.14e-58: 179: 98.41
+	Rn
		1026934 TSPY1_RAT (114-400): 6.97e-61: 209: 31.37		H2B1_RAT (1-126): 1.58e-54: 169: 96.03
+	Hs
		1163166 NP1L4_HUMAN (156-406): 2.96e-54: 192: 13.82		H2B2E_HUMAN (1-126): 3.14e-58: 179: 98.41
+	Hs
		449776 NP1L4_HUMAN (156-406): 2.96e-54: 192: 13.82		H2B1J_HUMAN (1-126): 3.7e-58: 179: 97.62
+	Hs
		754959 NP1L4_HUMAN (156-406): 2.96e-54: 192: 13.82		H2B1B_HUMAN (1-126): 8.04e-58: 178: 98.41
+	Hs
		1323963 NP1L4_HUMAN (156-406): 2.96e-54: 192: 13.82		H2B3B_HUMAN (1-126): 1.39e-55: 172: 96.03
+	Hs
		946755 SET_HUMAN (174-398): 2e-51: 182: 31.06		H2B1D_HUMAN (1-126): 1.09e-57: 178: 99.21
+	Hs
		936701 NP1L1_HUMAN (179-442): 2.89e-48: 176: 15.19		H2B1C_HUMAN (1-126): 4.5e-58: 179: 99.21
+	Hs
		936763 NP1L1_HUMAN (179-442): 2.89e-48: 176: 15.19		H2B2E_HUMAN (1-126): 3.14e-58: 179: 98.41
+	Hs
		754774 NP1L1_HUMAN (179-442): 2.89e-48: 176: 15.19		H2B1B_HUMAN (1-126): 8.04e-58: 178: 98.41
+	Hs
		1381850 NP1L4_HUMAN (156-406): 2.96e-54: 192: 13.82		H2B1A_HUMAN (1-126): 1.5e-49: 157: 85.83
+	Hs
		936805 NP1L1_HUMAN (179-442): 2.89e-48: 176: 15.19		H2B3B_HUMAN (1-126): 1.39e-55: 172: 96.03
+	Hs
		1029354 SET_HUMAN (174-398): 2e-51: 182: 31.06		H2B1A_HUMAN (1-126): 1.5e-49: 157: 85.83
+	Hs
		936830 NP1L1_HUMAN (179-442): 2.89e-48: 176: 15.19		H2B1A_HUMAN (1-126): 1.5e-49: 157: 85.83
+	Sc
		381414 NAP1_YEAST (128-438): 3.63e-42: 160: 14.86		H2B2_YEAST (3-127): 7.4e-45: 145: 69.60
+	Sc
		380981 NAP1_YEAST (128-438): 3.63e-42: 160: 14.86		H2B1_YEAST (3-127): 2.53e-38: 129: 69.60
+	Dm
		380881 Q24150_DROME (209-378): 6.33e-16: 82.2: 16.67		H2B_DROME (36-126): 4.66e-48: 153: 94.51